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Glycitein

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Glycitein Basic information
Glycitein Chemical Properties
  • Melting point:>300°C
  • Boiling point:547.4±50.0 °C(Predicted)
  • Density 1.420±0.06 g/cm3(Predicted)
  • storage temp. -20°C
  • pka7.03±0.20(Predicted)
  • InChIKeyDXYUAIFZCFRPTH-UHFFFAOYSA-N
  • CAS DataBase Reference40957-83-3(CAS DataBase Reference)
Safety Information
  • Hazard Codes Xi
  • Safety Statements 24/25
  • WGK Germany 3
  • HS Code 29329990
MSDS
Glycitein Usage And Synthesis
  • DescriptionGlycitein is an O-methylated isoflavone that comprises 5-10% of the total isoflavones in soy food products. This phytoestrogen is reported to have weak estrogenic activity, displacing estradiol binding at the estrogen receptor in vitro with an IC50 value of 3.94 μM. It suppresses the proliferation of osteoblasts and promotes differentiation from its progenitor. It has also been used to attenuate proliferation (10 μM) of aortic smooth muscle cells related to atherosclerotic vascular change in stroke-prone hypertensive rats and to protect against beta amyloid (Aβ)-induced toxicity and oxidative stress (100 μg/ml) in C. elegans expressing human Aβ.
  • Chemical PropertiesPale Orange Solid
  • Uses
    Glycitein may be used as a reference standard in the determination of glycitein in hydrolyzed dry soya extracts using reversed-phase high-performance liquid chromatography (RP-HPLC).
  • UsesThe compund shows an anti-cancer activity, plasma cholesterol reduction, reduction in postmenopausal bone loss
  • DefinitionChEBI: A methoxyisoflavone that is isoflavone substituted by a methoxy group at position 6 and hydroxy groups at positions 7 and 4'. It has been isolated from the mycelia of the fungus Cordyceps sinensis.
  • General Description
    Glycitein is an isoflavone found in soy food products.
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