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Pilocarpine nitrate

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Pilocarpine nitrate Basic information
Pilocarpine nitrate Chemical Properties
  • Melting point:173,5-174°C
  • alpha D +77 to +83° (c = 10)
  • refractive index 81 ° (C=2, H2O)
  • storage temp. 2-8°C
  • solubility H2O: 0.1 g/mL, clear, very faintly yellow
  • form powder
  • color white
  • optical activity[α]25/D +83°, c = 10 in H2O(lit.)
  • Merck 14,7424
  • BRN 4171406
  • CAS DataBase Reference148-72-1(CAS DataBase Reference)
  • EPA Substance Registry SystemPilocarpine nitrate (148-72-1)
Safety Information
  • Hazard Codes Xn,T+
  • Risk Statements 22-26/28
  • Safety Statements 1-25-45
  • RIDADR 3087
  • WGK Germany 3
  • RTECS TK1455000
  • 3-10
  • HazardClass 6.1(b)
  • PackingGroup III
  • HS Code 2939800000
  • ToxicityLD50 oral in rat: 911mg/kg
MSDS
Pilocarpine nitrate Usage And Synthesis
  • Chemical PropertiesWhite or almost white, crystalline powder or colourless crystals, sensitive to light.
  • Usesantiglaucoma agent, miotic
  • UsesAntiglaucoma drug;Cholinergic
  • brand namePilagan (Allergan).
  • General DescriptionPilocarpine mononitrate occursas shining white crystals that are not hygroscopic butare light sensitive. It is soluble in water (1:4) and alcohol(1:75) but insoluble in chloroform and ether. Aqueoussolutions are slightly acid to litmus and may be sterilizedin the autoclave. The alkaloid is incompatible with alkalies,iodides, silver nitrate, and reagents that precipitatealkaloids.
Pilocarpine nitrate(148-72-1)Related Product Information
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  • Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
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