Basic information Hypericum perforatum extracts Indications Uses Safety Related Supplier
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Hypericin

Basic information Hypericum perforatum extracts Indications Uses Safety Related Supplier
Hypericin Basic information
Hypericin Chemical Properties
  • Melting point:299-301°C
  • Boiling point:1020.3±65.0 °C(Predicted)
  • Density 1.915±0.06 g/cm3(Predicted)
  • RTECS SF8472000
  • storage temp. Store at +4°C
  • solubility 1 M NaOH: 10 mg/mL
  • form powder
  • pka6.91±0.20(Predicted)
  • color black
  • Water Solubility Soluble in ethanol, dimethyl sulfoxide, methanol, acetone, ethylmethylketone, pyridine and sodium hydroxide. Insoluble in water.
  • Sensitive Light Sensitive
  • Merck 14,4863
  • BRN 1917913
  • InChIKeyBTXNYTINYBABQR-UHFFFAOYSA-N
  • CAS DataBase Reference548-04-9(CAS DataBase Reference)
Safety Information
  • Hazard Codes Xn
  • Risk Statements 22-40-43
  • Safety Statements 22-36-36/37
  • RIDADR 2811
  • WGK Germany 3
  • 8
  • HS Code 29145090
MSDS
Hypericin Usage And Synthesis
  • Hypericum perforatum extractsHypericin is an extract of Hypericum perforatum L.In 1957. It is first isolated from the Garcinia species Hypericum perforatum by human beings. Hypericin belongs to the bianthrone compounds, and it is the most biologically active substances. Hypericin is a yellowish brown to brown mobile powder, with slightly bitter taste. It is soluble in water, and can emit a special fragrance. It can inhibit the central nervous and has a sedative effect. Adding it to health care products can enhance immunity. It is also used as antidepressant drugs in Europe (especially in Germany). Hypericin also has a strong anti-viral effect, which can directly act on swine fever, foot and mouth disease and other viruses. In addition, it also has a good effect on killing highly pathogenic avian influenza virus.
    Hypericum perforatum is one of the world's best-selling herbs in recent years, mainly containing hyperoside, quercetin, chlorogenic acid, caffeic acid, imanin, hypericin and other ingredients.
    Hypericin is a few thousandths of the whole Hypericum perforatum. There are certain requirements for its extraction and testing. Methanol extraction method is common used in the past. Due to the toxicity of methanol, now the method is   converted to use ethanol to obtain the active ingredient.
  • IndicationsHypericin is an anti-virus and pure Chinese medicine preparations. It is the first choice for the prevention and treatment of avian influenza drugs.
    1, avian influenza, atypical Newcastle disease, infectious bronchitis, avian infectious laryngotracheitis , bursa of Fabricius, duck plague, duck viral hepatitis, egg drop syndrome and other viral diseases.
    2, poultry fever caused by high fever, dyspnea, cough, head and face swelling, crown hair purple, lack of energy, decreased feed intake, egg drop, producing more abnormal eggs.
    3, for classical swine fever, blue ear disease, parvovirus, viral enteritis, infectious gastroenteritis and immune dysfunction.
    4, Hypericin has a strong anti-viral effect both in vivo and in vitro. It has a strong inhibitory effect on the early replication of HIV. Hypericin can lead to cancer cell programmed death, with anti-cancer effect. It has a enhanced immune function  for activating mononuclear phagocytic cells. In addition, it has a strong role in killing the highly pathogenic H5N1 and H9N2 subtype of avian influenza virus.
  • Uses(1) Antidepressant, increase immunity.
    (2) For the treatment of antidepressants, increase immunity.
  • Chemical PropertiesPowder
  • Biological ActivityPhotosensitive antiviral, anticancer and antidepressant agent derived from Hypericum perforatum (St John's wort). Inactivates enveloped viruses (including HIV), inhibits tyrosine kinases (IC 50 = 7.5 μ M) and is preferentially cytotoxic to tumor cells upon stimulation by visible light.
  • Purification MethodsCrystallise hypericin from pyridine by addition of methanolic HCl. [Beilstein 8 IV 3761.]
Hypericin(548-04-9)Related Product Information
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