Hypericum perforatum extracts Indications Uses
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Hypericin

Hypericum perforatum extracts Indications Uses
Hypericin Structure
Hypericin
  • CAS No.548-04-9
  • Chemical Name:Hypericin
  • CBNumber:CB2696784
  • Molecular Formula:C30H16O8
  • Formula Weight:504.44
  • MOL File:548-04-9.mol
Hypericin Property
  • Melting point: :299-301°C
  • Boiling point: :1020.3±65.0 °C(Predicted)
  • Density  :1.915±0.06 g/cm3(Predicted)
  • RTECS  :SF8472000
  • storage temp.  :-20°C
  • solubility  :1 M NaOH: 10 mg/mL
  • form  :powder
  • pka :6.91±0.20(Predicted)
  • color  :black
  • Water Solubility  :Soluble in ethanol, dimethyl sulfoxide, methanol, acetone, ethylmethylketone, pyridine and sodium hydroxide. Insoluble in water.
  • Sensitive  :Light Sensitive
  • Merck  :14,4863
  • BRN  :1917913
  • InChIKey :BTXNYTINYBABQR-UHFFFAOYSA-N
  • CAS DataBase Reference :548-04-9(CAS DataBase Reference)
  • FDA UNII :7V2F1075HD
Safety
  • Hazard Codes  :Xn
  • Risk Statements  :22-40-43
  • Safety Statements  :22-36-36/37
  • RIDADR  :2811
  • WGK Germany  :3
  • F  :8
  • HS Code  :29145090
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H317
  • Precautionary statements P280-P301+P312+P330-P261-P280g-P301+P312a-P321-P333+P313-P501a
Hypericin Price More Price(12)
  • Brand: Sigma-Aldrich
  • Product number: 400076-M
  • Product name : Hypericin - CAS 548-04-9 - Calbiochem
  • Purity: Polycyclic dione that has anti-retroviral activity.
  • Packaging: 1 mg
  • Price: $146.15
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 400076-M
  • Product name : Hypericin
  • Purity: Polycyclic dione that has anti-retroviral activity.
  • Packaging: 1mg-m
  • Price: $158
  • Updated: 2020/08/18
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: PHL89226
  • Product name : Hypericin
  • Purity: phyproof? Reference Substance
  • Packaging: 10 mg
  • Price: $523
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 00190585
  • Product name : Hypericin
  • Purity: primary pharmaceutical reference standard
  • Packaging: 10mg
  • Price: $713
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Alfa Aesar
  • Product number: H26425
  • Product name : Hypericin, 98%
  • Purity: 
  • Packaging: 100mg
  • Price: $1480
  • Updated: 2020/06/24
  • Buy: Buy

Hypericin Chemical Properties,Usage,Production

  • Hypericum perforatum extracts Hypericin is an extract of Hypericum perforatum L.In 1957. It is first isolated from the Garcinia species Hypericum perforatum by human beings. Hypericin belongs to the bianthrone compounds, and it is the most biologically active substances. Hypericin is a yellowish brown to brown mobile powder, with slightly bitter taste. It is soluble in water, and can emit a special fragrance. It can inhibit the central nervous and has a sedative effect. Adding it to health care products can enhance immunity. It is also used as antidepressant drugs in Europe (especially in Germany). Hypericin also has a strong anti-viral effect, which can directly act on swine fever, foot and mouth disease and other viruses. In addition, it also has a good effect on killing highly pathogenic avian influenza virus.
    Hypericum perforatum is one of the world's best-selling herbs in recent years, mainly containing hyperoside, quercetin, chlorogenic acid, caffeic acid, imanin, hypericin and other ingredients.
    Hypericin is a few thousandths of the whole Hypericum perforatum. There are certain requirements for its extraction and testing. Methanol extraction method is common used in the past. Due to the toxicity of methanol, now the method is   converted to use ethanol to obtain the active ingredient.
  • Indications Hypericin is an anti-virus and pure Chinese medicine preparations. It is the first choice for the prevention and treatment of avian influenza drugs.
    1, avian influenza, atypical Newcastle disease, infectious bronchitis, avian infectious laryngotracheitis , bursa of Fabricius, duck plague, duck viral hepatitis, egg drop syndrome and other viral diseases.
    2, poultry fever caused by high fever, dyspnea, cough, head and face swelling, crown hair purple, lack of energy, decreased feed intake, egg drop, producing more abnormal eggs.
    3, for classical swine fever, blue ear disease, parvovirus, viral enteritis, infectious gastroenteritis and immune dysfunction.
    4, Hypericin has a strong anti-viral effect both in vivo and in vitro. It has a strong inhibitory effect on the early replication of HIV. Hypericin can lead to cancer cell programmed death, with anti-cancer effect. It has a enhanced immune function  for activating mononuclear phagocytic cells. In addition, it has a strong role in killing the highly pathogenic H5N1 and H9N2 subtype of avian influenza virus.
  • Uses (1) Antidepressant, increase immunity.
    (2) For the treatment of antidepressants, increase immunity.
  • Chemical Properties Powder
  • Biological Activity Photosensitive antiviral, anticancer and antidepressant agent derived from Hypericum perforatum (St John's wort). Inactivates enveloped viruses (including HIV), inhibits tyrosine kinases (IC 50 = 7.5 μ M) and is preferentially cytotoxic to tumor cells upon stimulation by visible light.
  • Purification Methods Crystallise hypericin from pyridine by addition of methanolic HCl. [Beilstein 8 IV 3761.]
Hypericin Preparation Products And Raw materials
Raw materials
Preparation Products
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