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5-Bromouridine

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5-Bromouridine Basic information
5-Bromouridine Chemical Properties
  • Melting point:180-182 °C (dec.)(lit.)
  • alpha -11 º (c=2 in H2O)
  • Density 1.9322 (rough estimate)
  • refractive index 1.6520 (estimate)
  • storage temp.  0-6°C
  • optical activity[α]22/D 11°, c = 2 in H2O
  • Water Solubility Insoluble in water.
  • BRN 33664
  • CAS DataBase Reference957-75-5(CAS DataBase Reference)
Safety Information
  • Safety Statements 22-24/25
  • WGK Germany 3
  • RTECS YU7300000
  • 10
  • HS Code 29349990
MSDS
5-Bromouridine Usage And Synthesis
  • Chemical PropertiesWHITE FINE POWDER
  • Uses5-Bromouridine is a uridine (U829910) derivative and is often incorporated into RNA in order to detect immunocytochemically and analyzed by cytometry.
  • DefinitionChEBI: A uridine having a bromo substituent at the 5-position.
  • Purification MethodsRecrystallise it from 96% EtOH. UV max 279nm (log  3.95)in 2O pH 1.9. RF in n -BuOH/AcOH/H2O (4:4:1) is 0.49; in n-BuOH/EtOH/H2O (40:11:9) it is 0.46 and in isoPrOH/25%NH3/H2O (7:1:2) it is 0.53 using Whatman No 1 paper. [Pryst.s & Sorm Collect Czech Chem Commmun 29 2956 1964, Beilstein 31 H 24.]
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