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Muscone Basic information
  • Product Name:Muscone
  • CAS:541-91-3
  • MF:C16H30O
  • MW:238.41
  • EINECS:208-795-8
  • Mol File:541-91-3.mol
Muscone Chemical Properties
Safety Information
Muscone Usage And Synthesis
  • Chemical PropertiesMuscone is an odoriferous constituent of natural musk. It is a colorless liquid with very soft, sweet, musky odor and a perfumery, animal tonality.Numerous syntheses have been developed for its preparation including enantioselective methods to obtain the naturally occurring (3R)-enantiomer (l-muscone,. Because of its excellent stability, it can be used in awide range of products to give elegant,warm, animal notes. It is important for the reconstitution of naturalmusk.
  • Chemical PropertiesMusk is secreted exclusively by the male animals of Moschus moschiferus, a wild deer living in themountains of Nepal,Tibet, and Mongolia.Thelight yellow secretion with a salve consistency accumulates in the abdominal pouch and probably serves to attract the females. When the pouch is dried, the secretion solidifies to form a brittle, brown mass with a characteristic odor. Since several Moschus species occur, large variations exist in the quality and specifications of musk. Hunting of the animals has been prohibited; therefore, only small quantities ofmusk are occasionally offered at extremely high prices. In the United States and Europe, naturalmusk is no longer used as a fragrance ingredient.
  • Chemical Properties3-Methyl-1-cyclopentadecanone has a soft, sweet, tenacious, musky odor.
  • Chemical PropertiesColorless oily liquid
  • OccurrenceReported found in natural musk
  • UsesMuscone protects PC12 cells against glutamate-induced apoptosis.
  • PreparationFrom condensation of dodecamethyl-ene-α,ω-dimethylketone hexadecane.
  • Aroma threshold valuesDetection: 9.8 ppb
  • Synthesis Reference(s)The Journal of Organic Chemistry, 45, p. 1906, 1980 DOI: 10.1021/jo01298a029
    Tetrahedron Letters, 17, p. 2617, 1976
  • Safety ProfileLow oral and skin contact toxicity. A skin irritant. A flammable liquid. When heated to decomposition it emits acrid smoke and irritating fumes.
Muscone Preparation Products And Raw materials
Muscone(541-91-3)Related Product Information
  • Company Name:Nanjing Dasf Biotechnology Co., Ltd. Gold
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