萘啶酮酸钠
萘啶酮酸钠 性质
| 熔点 | >280℃ |
|---|---|
| 储存条件 | Inert atmosphere,Room Temperature |
| 溶解度 | H2O：50 mg/mL，清澈，淡黄色 |
| 形态 | 粉末 |
| 颜色 | 白色至米白色 |
| 水溶解性 | Soluble at 50mg/ml in water |
| BRN | 3580062 |
| InChI | InChI=1S/C12H12N2O3.Na.H/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14;;/h4-6H,3H2,1-2H3,(H,16,17);; |
| InChIKey | XVRRVENPZKMSNF-UHFFFAOYSA-N |
| SMILES | C(N1C=C(C(=O)O)C(=O)C2=CC=C(C)N=C12)C.[NaH] |
| CAS 数据库 | 3374-05-8(CAS DataBase Reference) |
萘啶酮酸钠 用途与合成方法
|
Topoisomerase
|
Nalidixic acid is against a variety of microorganisms, it is against with Escherichia coli , Pasteurella spp. , Klebsiella pneuiiioniae , Aerobacter aeroyenes , Proteus spp. , Salmonella spp. , Shigella spp. and Brucella spp. with MIC values of 5.0-12.5 μg/ml, 0.5-2.5 μg/ml, 0.8-25.0 μg/ml, 1.0-25.0 μg/ml, 1.25-30.0 μg/ml, 8-3.2 μg/ml, and 7.5-10.0 μg/ml, respectively.
The in vivo activity of Nalidixic acid is most pronounced against Gram-negative bacteria, while Gram-positive organisms are generally more resistant. Maximal activity is observed against systemic infections caused by E. coli , A. aerobacter , Proteus mirabilis , Shigella fkxneri , the ED 50 values are 25 mg/kg, 60 mg/kg, 50 mg/kg, and 62 mg/kg, respectively. The acute toxicity (LD 50 ) of Nalidixic acid in mice following oral and parenteral administration is: oral, 3300 mg/kg; intravenous, 176 mg/kg; and subcutaneous, 500 mg/kg.
安全信息
| 危险品标志 | Xn |
|---|---|
| 危险类别码 | 42/43 |
| 安全说明 | 22-36/37-45 |
| WGK Germany | - |
| RTECS号 | QN2885500 |
| F | 8-10 |
| 海关编码 | 29339900 |
| 存储类别 | 11 - 可燃固体 |
| 危险性类别 | 急性毒性 类别4 经口 生殖毒性 类别2 呼吸道致敏物 类别1 皮肤致敏物 类别1 |
萘啶酮酸钠 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-09-15 | HY-B0398AR | 萘啶酮酸钠 | 3374-05-8 | 5 mg | 349 |
| 2026-09-15 | HY-B0398AR | 萘啶酮酸钠 | 3374-05-8 | 10 mg | 524 |
