萘啶酮酸钠
萘啶酮酸钠 性质
熔点 | >280℃ |
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储存条件 | Inert atmosphere,Room Temperature |
溶解度 | H2O:50 mg/mL,清澈,淡黄色 |
形态 | 粉末 |
颜色 | 白色至米白色 |
水溶解性 | Soluble at 50mg/ml in water |
BRN | 3580062 |
CAS 数据库 | 3374-05-8(CAS DataBase Reference) |
萘啶酮酸钠 用途与合成方法
Topoisomerase
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Nalidixic acid is against a variety of microorganisms, it is against with Escherichia coli , Pasteurella spp. , Klebsiella pneuiiioniae , Aerobacter aeroyenes , Proteus spp. , Salmonella spp. , Shigella spp. and Brucella spp. with MIC values of 5.0-12.5 μg/ml, 0.5-2.5 μg/ml, 0.8-25.0 μg/ml, 1.0-25.0 μg/ml, 1.25-30.0 μg/ml, 8-3.2 μg/ml, and 7.5-10.0 μg/ml, respectively.
The in vivo activity of Nalidixic acid is most pronounced against Gram-negative bacteria, while Gram-positive organisms are generally more resistant. Maximal activity is observed against systemic infections caused by E. coli , A. aerobacter , Proteus mirabilis , Shigella fkxneri , the ED 50 values are 25 mg/kg, 60 mg/kg, 50 mg/kg, and 62 mg/kg, respectively. The acute toxicity (LD 50 ) of Nalidixic acid in mice following oral and parenteral administration is: oral, 3300 mg/kg; intravenous, 176 mg/kg; and subcutaneous, 500 mg/kg.
萘啶酮酸钠 价格(试剂级)
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024-11-11 | XW337405802 | 萘啶酸钠盐 | 3374-05-8 | 5G | 300 |
2024-11-11 | XW337405801 | 萘啶酸钠盐 | 3374-05-8 | 1G | 108 |