3374-05-8
基本信息
1-乙基-1,4-二氢-7-甲基-4-氧代-1,8-萘啶-3-羧酸钠盐
萘啶酮酸钠
NALIDIXIC ACID SODIUM SALT
1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylicacidsodium
8-naphthyridine-3-carboxylicacid,1-ethyl-1,4-dihydro-7-methyl-4-oxo-sodiu
nalidixatesodium
sodiumnalidixate
sodiumnilixalate
nalidixic acid sodium
nalidixic acid sodium gamma-irradiated*molecular
sodium 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylate
NALIDIXIC ACID SODIUM GAMMA-IRRADIATED*M OLECULAR BI
NALIDIXIC ACID SODIUM SALT MOLECULAR BIOLOGY REAGENT
1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-1,4-dihydro-7-methyl-4-oxo-, sodium salt
1,4-Dihydro-1-ethyl-4-oxo-7-methyl-1,8-naphthyridine-3-carboxylic acid sodium salt
1-Ethyl-4-oxo-7-methyl-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid sodium salt
物理化学性质
| 熔点 | >280℃ |
| 储存条件 | 2-8°C |
| 溶解度 | H2O: 50 mg/mL, clear, faintly yellow |
| 形态 | powder |
| 形态 | 粉末 |
| 颜色 | White to off-white |
| 水溶解性 | Soluble at 50mg/ml in water |
| BRN | 3580062 |
| CAS 数据库 | 3374-05-8(CAS DataBase Reference) |
安全数据
| 危险性符号(GHS) |   GHS07,GHS08 |
| 警示词 | 警告 |
| 危险性描述 | H302-H351 |
| 防范说明 | P202-P264-P270-P280-P301+P312-P308+P313 |
| 危险品标志 | Xn |
| 危险类别码 | R42/43 |
| 安全说明 | S22-S36/37-S45 |
| WGK Germany | - |
| RTECS号 | QN2885500 |
| F | 8-10 |
| 海关编码 | 29339900 |
知名试剂公司产品信息
萘啶酮酸钠价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/11/11 | XW337405802 | 萘啶酸钠盐 | 3374-05-8 | 5G | 300元 |
| 2024/11/11 | XW337405801 | 萘啶酸钠盐 | 3374-05-8 | 1G | 108元 |
| 2024/11/08 | 46355 | 萘啶酸钠盐 Nalidixic acid sodium salt, Thermo Scientific Chemicals | 3374-05-8 | 1g | 470元 |
常见问题列表
|
Topoisomerase
|
Nalidixic acid is against a variety of microorganisms, it is against with Escherichia coli , Pasteurella spp. , Klebsiella pneuiiioniae , Aerobacter aeroyenes , Proteus spp. , Salmonella spp. , Shigella spp. and Brucella spp. with MIC values of 5.0-12.5 μg/ml, 0.5-2.5 μg/ml, 0.8-25.0 μg/ml, 1.0-25.0 μg/ml, 1.25-30.0 μg/ml, 8-3.2 μg/ml, and 7.5-10.0 μg/ml, respectively.
The in vivo activity of Nalidixic acid is most pronounced against Gram-negative bacteria, while Gram-positive organisms are generally more resistant. Maximal activity is observed against systemic infections caused by E. coli , A. aerobacter , Proteus mirabilis , Shigella fkxneri , the ED 50 values are 25 mg/kg, 60 mg/kg, 50 mg/kg, and 62 mg/kg, respectively. The acute toxicity (LD 50 ) of Nalidixic acid in mice following oral and parenteral administration is: oral, 3300 mg/kg; intravenous, 176 mg/kg; and subcutaneous, 500 mg/kg.