Basic information Description Indication Contraindications Dosage Mechanism of Action Elimination Adverse reactions Precautions Safety Related Supplier
Azacitidine Structure

Azacitidine

Chemical Properties

Melting point 226-232 °C (dec.)(lit.)
alpha  40 º (C=1, H2O 22 ºC)
Boiling point 387.12°C (rough estimate)
Density  1.4287 (rough estimate)
refractive index  1.6590 (estimate)
storage temp.  -20°C
solubility  Soluble in DMSO (up to 25 mg/ml), or in Water (up to 12 mg/ml).
pka 13.46±0.70(Predicted)
form  lyophilized powder
color  White to Off-white
Water Solubility  0.5-1.0 g/100 mL at 21 ºC
Merck  14,887
BRN  620461
Stability Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
InChIKey NMUSYJAQQFHJEW-WGDKFINWSA-N
LogP -2.191 (est)
CAS DataBase Reference 320-67-2(CAS DataBase Reference)
IARC 2A (Vol. 50) 1990
EPA Substance Registry System Azacitidine (320-67-2)

Safety Information

Hazard Codes  T
Risk Statements  45-46-22
Safety Statements  53-22-36/37/39-45
WGK Germany  3
RTECS  XZ3017500
10-23
HS Code  29349990
Hazardous Substances Data 320-67-2(Hazardous Substances Data)
Toxicity LD50 in mice (mg/kg): 115.9 i.p.; 572.3 orally (Palm, Kensler)

MSDS

Usage And Synthesis

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