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Gastrointestinal antispasmodic drugs
Gastrointestinal antispasmodic drugs
Gastrointestinal antispasmodic drugs are mainly M receptor blockers, briefly referred to as anticholinergics, including belladonna alkaloids and their derivatives and artificial synthetic substitutes. For example: atropine, anisodamine, scopolamine, belladonna, trimebutine, and propanthine.
Mechanism These drugs function mainly through weakening the peristalsis function of the gastrointestinal tract, causing relaxation of the esophagus and gastrointestinal sphincter, thereby slowing down the stomach emptying and intestinal transport, weakening the gallbladder contraction and reducing the gallbladder pressure as well as weakening the colon peristalsis and slowing down the transport of colon contents.
Clinical anticholinergic drugs has atropine be the typical representative, mainly used for treating gastrointestinal dysfunction, relieving visceral colic, treating acute microcirculation and various kind of toxic shock and poisoning rescue and so on.
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- Structure:
- Chemical Name:Oxapium iodide
- CAS:6577-41-9
- MF:C22H34INO2
- Structure:
- Chemical Name:butetamate
- CAS:14007-64-8
- MF:C16H25NO2
- Structure:
- Chemical Name:Pipethanate
- CAS:4546-39-8
- MF:C21H25NO3
- Structure:
- Chemical Name:1-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-1-methyl-3,4,5,6-tetrahydro-2H-pyridine bromide
- CAS:21216-78-4
- MF:C22H28BrNO2
- Structure:
- Chemical Name:Pyrrolidinium, 3-[[(2R)-2-cyclopentyl-2-hydroxy-2-phenylacetyl]oxy]-1,1-dimethyl-, (3S)-rel-
- CAS:740028-90-4
- MF:C19H28NO3+
- Structure:
- Chemical Name:Tiropramide
- CAS:55837-29-1
- MF:C28H41N3O3
- Structure:
- Chemical Name:(S)-Oxybutynin hydrochloride
- CAS:230949-16-3
- MF:C22H32ClNO3
- Structure:
- Chemical Name:Dihexyverine
- CAS:561-77-3
- MF:C20H35NO2
- Structure:
- Chemical Name:Pramiverine
- CAS:14334-40-8
- MF:C21H27N
- Structure:
- Chemical Name:METHANTHELINE BROMIDE
- CAS:53-46-3
- MF:CH3-
- Structure:
- Chemical Name:hexocyclium metilsulfate
- CAS:115-63-9
- MF:C21H36N2O5S
- Structure:
- Chemical Name:ethaverine
- CAS:486-47-5
- MF:C24H29NO4
- Structure:
- Chemical Name:MG 624
- CAS:77257-42-2
- MF:C22H30INO
- Structure:
- Chemical Name:Atropine N-oxide hydrochloride
- CAS:4574-60-1
- MF:C17H23NO4.ClH
- Structure:
- Chemical Name:Benzenepropanoic acid, 4-chloro-b-[[[[(1S)-2-Methyl-1-(2-Methyl-1-oxopropoxy)propoxy]carbonyl ]aMino]Methyl]-, (bR)-
- CAS:847353-30-4
- MF:C19H26ClNO6
- Structure:
- Chemical Name:TRIDIHEXETHYL CHLORIDE (200 MG)
- CAS:4310-35-4
- MF:C21H35ClNO
- Structure:
- Chemical Name:ethaverine hydrochloride
- CAS:985-13-7
- MF:C24H29NO4.ClH
- Structure:
- Chemical Name:Piperilate hydrochloride
- CAS:4544-15-4
- MF:C21H25NO3.ClH
- Structure:
- Chemical Name:Propenzolate
- CAS:1420-03-7
- MF:
- Structure:
- Chemical Name:2-(alpha-cyclopentyl-alpha-2-thienylglycolloyloxy)ethyldiethyl(methyl)ammonium bromide
- CAS:60-44-6
- MF:C18H30BrNO3S
- Structure:
- Chemical Name:rociverine
- CAS:53716-44-2
- MF:C20H37NO3
- Structure:
- Chemical Name:moxaverine
- CAS:10539-19-2
- MF:C20H21NO2
- Structure:
- Chemical Name:Fentonium
- CAS:5868-06-4
- MF:C31H34BrNO4
- Structure:
- Chemical Name:tarazepide
- CAS:141374-81-4
- MF:C28H24N4O2
- Structure:
- Chemical Name:Alverine
- CAS:150-59-4
- MF:C20H27N
- Structure:
- Chemical Name:FENOVERINE
- CAS:37561-27-6
- MF:C26H25N3O3S
- Structure:
- Chemical Name:bevonium metilsulfate
- CAS:5205-82-3
- MF:C23H31NO7S
- Structure:
- Chemical Name:Denaverine
- CAS:3321-06-0
- MF:C24H34ClNO3
- Structure:
- Chemical Name:Polyphloroglucinol phosphate
- CAS:51202-77-8
- MF:C6H7O6P
- Structure:
- Chemical Name:FENPIVERINIUM BROMIDE
- CAS:125-60-0
- MF:C22H29BrN2O
- Structure:
- Chemical Name:prifinium bromide
- CAS:4630-95-9
- MF:C22H28BrN
- Structure:
- Chemical Name:diponium bromide
- CAS:2001-81-2
- MF:C20H38NO2.Br
- Structure:
- Chemical Name:diisopromine
- CAS:5966-41-6
- MF:C21H29N
- Structure:
- Chemical Name:fencarbamide
- CAS:3735-90-8
- MF:C19H24N2OS
- Structure:
- Chemical Name:Benzetimide
- CAS:119391-55-8
- MF:C23H26N2O2
- Structure:
- Chemical Name:Triampyzine
- CAS:7082-30-6
- MF:C9H17N3O4S
- Structure:
- Chemical Name:3-Bromopropionic acid
- CAS:590-92-1
- MF:C3H5BrO2
- Structure:
- Chemical Name:Glycopyrronium tosylate
- CAS:1624259-25-1
- MF:C26H35NO6S
- Structure:
- Chemical Name:PARGEVERINE HCL
- CAS:13479-13-5
- MF:C21H23NO3
- Structure:
- Chemical Name:butropium bromide
- CAS:29025-14-7
- MF:C28H38NO4.Br
- Structure:
- Chemical Name:pentapiperium metilsulfate
- CAS:7681-80-3
- MF:C19H30NO2.CH3O4S
- Structure:
- Chemical Name:Difemerine
- CAS:80387-96-8
- MF:C20H25NO3
- Structure:
- Chemical Name:Methylbenactyzine bromide
- CAS:3166-62-9
- MF:C21H30BrNO4
- Structure:
- Chemical Name:dicycloverine
- CAS:77-19-0
- MF:C19H35NO2
- Structure:
- Chemical Name:etomidoline
- CAS:21590-92-1
- MF:C23H29N3O2
- Structure:
- Chemical Name:benzilonium bromide
- CAS:1050-48-2
- MF:C22H28BrNO3
- Structure:
- Chemical Name:[7(S)-(1alpha2beta,4beta,5alpha,7beta)]-7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane methyl sulphate
- CAS:18067-13-5
- MF:C19H27NO8S
- Structure:
- Chemical Name:oxyphencyclimine
- CAS:125-53-1
- MF:C20H28N2O3
- Structure:
- Chemical Name:Pipoxolan Hcl
- CAS:23744-24-3
- MF:C22H25NO3
- Structure:
- Chemical Name:Aklonin
- CAS:31031-74-0
- MF:C13H20ClNO2
- Structure:
- Chemical Name:Denaverine
- CAS:3579-62-2
- MF:C24H33NO3
- Structure:
- Chemical Name:N-[2-[4-(2-Diethylaminoethoxy)phenyl]-1-(dipropylcarbamoyl)ethyl]benzamide hydrochloride
- CAS:57227-16-4
- MF:C28H42ClN3O3
- Structure:
- Chemical Name:Papaverine sulfate
- CAS:32808-09-6
- MF:C20H23NO8S
- Structure:
- Chemical Name:2-piperidinoethyl [1,1'-bicyclohexyl]-1-carboxylate hydrochloride
- CAS:5588-25-0
- MF:C20H36ClNO2
- Chemical Name:DipenineBromide
- CAS:
- MF:
- Structure:
- Chemical Name:Valethamate bromide
- CAS:90-22-2
- MF:C19H32BrNO2
- Structure:
- Chemical Name:Methscopolamine bromide
- CAS:155-41-9
- MF:C18H24BrNO4
- Structure:
- Chemical Name:Benactyzine hydrochloride
- CAS:57-37-4
- MF:C20H26ClNO3
- Structure:
- Chemical Name:Mebeverine hydrochloride
- CAS:2753-45-9
- MF:C25H35NO5.ClH
- Structure:
- Chemical Name:Gefarnate
- CAS:51-77-4
- MF:C27H44O2
- Structure:
- Chemical Name:Isocorydine hydrochloride
- CAS:13552-72-2
- MF:C20H24ClNO4
- Structure:
- Chemical Name:octamylamine
- CAS:502-59-0
- MF:C40H88N
- Structure:
- Chemical Name:Oxyphenonium bromide
- CAS:50-10-2
- MF:C21H34BrNO3
- Structure:
- Chemical Name:MethylbenactyziumBromide
- CAS:
- MF:C21H28BrNO3
- Structure:
- Chemical Name:Adiphenine hydrochloride
- CAS:50-42-0
- MF:C20H25NO2.ClH
- Structure:
- Chemical Name:MEBEVERINE
- CAS:3625-06-7
- MF:C25H35NO5
- Structure:
- Chemical Name:L-Hyoscyamine
- CAS:101-31-5
- MF:C17H23NO3
- Structure:
- Chemical Name:Propantheline bromide
- CAS:50-34-0
- MF:C23H30NO3.Br
- Structure:
- Chemical Name:Swertiamarine
- CAS:17388-39-5
- MF:C16H22O10
- Structure:
- Chemical Name:Glycopyrrolate
- CAS:596-51-0
- MF:C19H28BrNO3-
- Structure:
- Chemical Name:Drotaverin hydrochloride
- CAS:14009-24-6
- MF:C24H31NO4
- Chemical Name:THYROGLOBULIN, HUMAN
- CAS:9010-34-8
- MF:
- Structure:
- Chemical Name:Tizanidine hydrochloride
- CAS:64461-82-1
- MF:C9H9Cl2N5S
- Structure:
- Chemical Name:Scopolamine butylbromide
- CAS:149-64-4
- MF:C21H30BrNO4
- Structure:
- Chemical Name:Drotaverine hydrochloride
- CAS:985-12-6
- MF:C24H32ClNO4
- Structure:
- Chemical Name:Tizanidine
- CAS:51322-75-9
- MF:C9H8ClN5S
- Structure:
- Chemical Name:Atropine methyl bromide
- CAS:2870-71-5
- MF:C18H26NO3.Br
- Structure:
- Chemical Name:isometheptene
- CAS:503-01-5
- MF:C9H19N
- Structure:
- Chemical Name:poldine metilsulfate
- CAS:545-80-2
- MF:C21H26NO3.CH3O4S