Colorless oily liquid. Boiling point 176-178°C, 58-59°C (0.93kPa). Relative density 0.795; refractive index 1.4472 (15℃) Soluble in ethanol, ether, acetone or chloroform, practically insoluble in water. Strongly alkaline, can volatilize with water vapor. Has ammonia odor.
6-Methylamino-2-methylheptene is an intermediate for the synthesis of Isometheptene Maleate (I821325), which belongs to a group of sympathomimetic amine and shows very little antihypertensive activity. Isometheptene Maleate is used as an antispasmodic drug.
ChEBI: Isometheptene is a secondary amino compound.
Methyl heptenone dissolved in 75% alcohol is reduced with activated
aluminum in the presence of methylamine to give isometheptene.
