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Scopolamine butylbromide

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Scopolamine butylbromide Basic information
Scopolamine butylbromide Chemical Properties
  • Melting point:142-1440C
  • alpha D20 -20.8° (c = 3 in water)
  • storage temp. -20°C Freezer, Under Inert Atmosphere
  • solubility H2O: 50 mg/mL
  • form powder
  • color white
  • optical activity[α]25/D 20.8°, c = 3 in H2O(lit.)
  • CAS DataBase Reference149-64-4(CAS DataBase Reference)
Safety Information
  • Hazard Codes Xn
  • Risk Statements 22
  • WGK Germany 3
  • RTECS YM3500000
  • ToxicityLD50 in mice (mg/kg): 15.6 i.v.; 74 i.p.; 570 s.c.; 3000 orally (Stockhaus, Wick)
MSDS
Scopolamine butylbromide Usage And Synthesis
  • Chemical PropertiesCrystalline Solid
  • OriginatorButylscopolamine,China Pharm
  • UsesAnticholinergic. Antispasmodic
  • Manufacturing Process1300 g of scopolamine base and 350 g of n-butylbromide in 600 ml acetonitrile is heated at 65°C for 160 hours. The oil obtained is dissolved in methanol. The solution is cooled and crystalline scopolamine N-n-butylbromide is filtered. After recrystallization from methanol was obtained scopolamine N-n-butylbromide with melting point 142-144°C and [α]d 20 = -20.5° (3% solution in water); yield 65%.
  • Therapeutic Function Anticholinergic, Spasmolytic, Antitussive
Scopolamine butylbromide(149-64-4)Related Product Information
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