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エタノール

エタノール 化学構造式
64-17-5
  • CAS番号.64-17-5
  • 化学名:エタノール
  • 别名:消毒用エタライト;オー消エタ;テクソール;消エタサラコール;アルコール;消毒用エタノールα;消毒用エタノール;酒精;メチルカルビノール;純生局エタ;水和エチル;エチルアルコール;消毒用エタIP;消エタコア;純生消エタ;消毒用エタライト-B;エタン-1-オール;消毒用エタノールIPA;エコ消エタ;エタノール
  • 英語化学名:Ethanol
  • 英語别名:RGA;etha;Spirt;C2H5OH;Jaysol;jiujin;Tecsol;Thanol;Etanol;Algrain
  • CBNumber:CB2362508
  • Molecular Formula:C2H6O
  • Formula Weight:46.07
  • MOL File:64-17-5.mol
エタノール 物理性質
  • 融点  :-114°C
  • 沸点  :78°C
  • 比重(密度)  :0.789 g/mL at 20 °C
  • 蒸気密度 :1.59 (vs air)
  • 蒸気圧 :43 mmHg at 20 °C
  • FEMA  :2419 | ETHYL ALCOHOL
  • 屈折率  :1.3614
  • 闪点  :12°C
  • 貯蔵温度  :room temp
  • 溶解性 :water: soluble (completely)
  • 酸解離定数(Pka) :16(at 25℃)
  • 外見  :Liquid. Colorless liquid / invisible vapor.
  • 色 :APHA: ≤10
  • 比重 :0.80872~0.81601
  • 臭い (Odor) :Pleasant alcoholic odor detectable at 49 to 716 ppm (mean = 180 ppm)
  • Relative polarity :0.654
  • PH :7.0 (10g/l, H2O, 20℃)
  • 爆発限界(explosive limit) :3.1-27.7%(V)(ethanol)
  • 臭気閾値(Odor Threshold) :0.52ppm
  • 水溶解度  :miscible
  • Sensitive  :Hygroscopic
  • 極大吸収波長 (λmax) :λ: 240 nm Amax: 0.40
    λ: 250 nm Amax: 0.30
    λ: 260 nm Amax: 0.30
    λ: 270 nm Amax: 0.10
    λ: 340 nm Amax: 0.10
  • JECFA Number :41
  • Merck  :14,3760
  • BRN  :1718733
  • 暴露限界値 :TLV-TWA 1900 mg/m3 (1000 ppm) (ACGIH).
  • 安定性: :Stable. Substances to be avoided include strong oxidizing agents, peroxides, acids, acid chlorides, acid anhydrides, alkali metals, ammonia, moisture. Forms explosive mixtures with air. Hygroscopic.
  • CAS データベース :64-17-5(CAS DataBase Reference)
  • NISTの化学物質情報 :Ethanol(64-17-5)
  • IARC :1 (Vol. 96, 100E) 2012
  • EPAの化学物質情報 :Ethanol (64-17-5)
安全性情報
危険有害性情報のコード(GHS)
  • 絵表示(GHS)
  • 注意喚起語Danger
  • 危険有害性情報
  • H225:引火性の高い液体および蒸気
  • H226:引火性の液体および蒸気
  • H302:飲み込むと有害
  • H313:皮膚に接触すると有害のおそれ
  • H319:強い眼刺激
  • H333:吸入すると有害のおそれ
  • H370:臓器の障害
  • H371:臓器の障害のおそれ
  • H402:水生生物に有害
  • H412:長期的影響により水生生物に有害
  • 注意書き
  • P210:熱/火花/裸火/高温のもののような着火源から遠ざ けること。-禁煙。
  • P260:粉じん/煙/ガス/ミスト/蒸気/スプレーを吸入しないこ と。
  • P280:保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。
  • P301+P310:飲み込んだ場合:直ちに医師に連絡すること。
  • P303+P361+P353:皮膚(または髪)に付着した場合:直ちに汚染された衣 類をすべて脱ぐこと/取り除くこと。皮膚を流水/シャワー で洗うこと。
  • P305+P351+P338:眼に入った場合:水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。
  • P311:医師に連絡すること。
  • P337+P313:眼の刺激が続く場合:医師の診断/手当てを受けること。
  • P370+P378:火災の場合:消火に...を使用すること。
  • P403+P235:換気の良い場所で保管すること。涼しいところに 置くこと。
  • P405:施錠して保管すること。
エタノール 価格 もっと(202)
  • メーカー: 富士フイルム和光純薬株式会社(wako)
  • 製品番号: W01W0105-0048
  • 製品説明 : エタノール (95)
  • 純度: Ethanol (95)94.8~95.8 vol% (by density)
  • 包装: 500mL
  • 価格: ¥2110
  • 更新時間: 2021/03/23
  • 購入: 購入
  • メーカー: 富士フイルム和光純薬株式会社(wako)
  • 製品番号: W01W0105-0047
  • 製品説明 : エタノール(95)
  • 純度: Ethanol(95)94.8?95.8 vol% (by density)
  • 包装: 500mL
  • 価格: ¥2210
  • 更新時間: 2021/03/23
  • 購入: 購入
  • メーカー: 関東化学株式会社(KANTO)
  • 製品番号: 14032-1B
  • 製品説明 : エタノール(99.5)
  • 純度: Ethanol (99.5)>99.5%(GC)
  • 包装: 1L
  • 価格: ¥5800
  • 更新時間: 2021/03/23
  • 購入: 購入
  • メーカー: 関東化学株式会社(KANTO)
  • 製品番号: 14032-08
  • 製品説明 : エタノール(99.5)
  • 純度: Ethanol (99.5)>99.5%(GC)
  • 包装: 500mL
  • 価格: ¥5000
  • 更新時間: 2021/03/23
  • 購入: 購入
  • メーカー: Sigma-Aldrich Japan
  • 製品番号: R3404
  • 製品説明 : 
  • 純度: 95%, Used for histology tissue preparation
  • 包装: 1 gal
  • 価格: ¥24300
  • 更新時間: 2021/03/23
  • 購入: 購入

Ethanol 化学特性,用途語,生産方法

  • 外観 無色透明な液体
  • 定義 本品は、エタノール(*)に、変性剤を加えたものである。参照表示名称:エタノール
  • 溶解性 水及びジエチルエーテルに極めて溶けやすい。
  • 解説 狭義には,エチルアルコールをさし,広義には,アルコール類を総称する.【Ⅰ】エチルアルコールの略称.エチルアルコールは人類の酒の歴史とともに古くから知られており,その組成は,17世紀にJ.L. Gay-Lussac(ゲイ-リュサック)やJ.B.A. Dumas(デュマ)により決定された.アルコール類のうちではもっとも一般的で,もっとも広い用途をもつエチルアルコールを単にアルコールと称することが多い.【Ⅱ】炭化水素の水素原子をヒドロキシ基で置換した化合物で,一般式ROHで表される.ただし,ヒドロキシ基がベンゼン環の炭素に直接結合したフェノール類はアルコール類には入らない.ヒドロキシ基の数により,一価アルコール,二価アルコール,三価アルコールなどとよび,また,ヒドロキシ基が結合している炭素原子の種類により,第一級アルコールR1CH2OH,第二級アルコールR1 R2CHOH,第三級アルコールR1 R2 R3COHに分類される.芳香族炭化水素の側鎖にヒドロキシ基の置換しているものは芳香族アルコールという.IUPAC命名法では,炭化水素名の語尾の-eを-olにかえ,メタンに対応するCH3OHをメタノールと命名する.二価および三価アルコールは,それぞれ語尾をジオール(-diol),トリオール(-triol)にかえる.普通には慣用名が用いられ,ヒドロキシ基と結合しているR基名の後にアルコールを付記して,“メチルアルコール”のように命名する.アルコール類は,多くはエステルとして自然界に存在する.一価アルコールの低級のものは植物精油中に,高級のものは動物,植物のろう中に存在する.三価アルコールのグリセリンは高級脂肪酸エステルとして油脂中に,ペンチトールやヘキシトールのような多価アルコールも動物,植物界に存在する.また,天然有機化合物にはヒドロキシ基をもつものが多い.多数の製法が知られている.(1)メタノールは一酸化炭素と水素の高圧接触反応によって工業的につくられる.(2)低級の飽和一価アルコール(C2~C5)は炭水化物やタンパク質の発酵によって生成する.(3)高級のものは天然産エステルの加水分解によっても得られる.(4)オレフィンの水和反応によって工業的に製造できる.(5)第一級アミンに亜硝酸を作用させる.(6)アルデヒドやケトンの接触還元により,それぞれ第一級アルコールおよび第二級アルコールが得られる.(7)脂肪酸エステルを水素化アルミニウムリチウムでアルコールにまで還元する.(8)複雑な構造をもつアルコール類は,アルデヒド,ケトン,エステルあるいはオキシドとグリニャール試薬との反応によって合成することができる.低級の一価アルコールは特有の味と香気をもつ液体で,水とよくまざるが,高級になるほど溶解度が減少し,C5 以上になるとほとんど水に溶けない.多価アルコールは水溶性の液体または固体で,多くは甘味をもつ.化学的には中性の化合物で,種々の無機塩と付加物をつくることがある.ヒドロキシ基の水素原子は金属と置換してアルコキシドを生じ,とくに低級の一価アルコールのアルコキシドは種々の反応の試薬として使われる.アルコールのヒドロキシ基は酸と脱水縮合すればエステルを,ハロゲン化水素またはハロゲン化リンと反応させればハロゲン化物を生成する.酸化すると,第一級アルコールはアルデヒドを経てカルボン酸となり,第二級アルコールはケトンを生成する.強酸の存在下に加熱脱水するとオレフィンを生じる.アルコール類の各種ヒドロキシ基は赤外線吸収スペクトルによって容易に同定できる.すなわち,3650~3200 cm-1 のO-Hの伸縮振動,1410~1050 cm-1 のC-O伸縮振動,およびO-H変角振動による特性吸収から,第一級,第二級,および第三級アルコールを区別することができる.化合物の同定は,アシル化,エステル化,ウレタン化により結晶性の誘導体に導いて行われる.
    森北出版「化学辞典(第2版)
  • 用途 多くのエチルアルコールは希釈してアルコール飲料、実験室用溶剤、変性アルコール、医薬品(消毒剤、ローション、トニック、コロン類)製造、香粧品工業、有機合成化学工業の溶剤、ガソリンのオクタン価向上剤、医薬品助剤(溶剤)
  • 用途 その他の代表用途は、工業用原料(洗剤、塗料、溶剤など)である。
  • 用途 汎用試薬(95%指定のもの)、溶剤等。
  • 用途 高純度溶媒を使用する小実験に、或いは使用中の汚染を避けるため小包装を必要とする場合に使用される。
  • 用途 汎用試薬(95%指定のもの)、溶剤、有機合成原料、試液調製原料、消毒殺菌剤。
  • 化粧品の成分用途 減粘剤、抗菌剤、溶剤、収れん剤、香料、消泡剤
  • 効能 抗悪性腫瘍薬, 外皮用殺菌消毒薬, 溶解剤
  • 主な用途/役割 溶剤型接着剤、水性型エマルション系接着剤、エアゾール接着剤に使用される。
  • 商品名 エタノール (小堺製薬); 無水エタノール (コニシ); 無水エタノール (サンケミファ); 無水エタノール (シオエ製薬); 無水エタノール (マイラン製薬); 無水エタノール (ヤクハン製薬); 無水エタノール (丸石製薬); 無水エタノール (丸石製薬); 無水エタノール (丸石製薬); 無水エタノール (今津薬品工業); 無水エタノール (健栄製薬); 無水エタノール (司生堂製薬); 無水エタノール (吉田製薬); 無水エタノール (大成薬品工業); 無水エタノール (小堺製薬); 無水エタノール (小堺製薬); 無水エタノール (山善製薬); 無水エタノール (扶桑薬品工業); 無水エタノール (日興製薬); 無水エタノール (日興製薬); 無水エタノール (日興製薬); 無水エタノール (東洋製薬化成); 無水エタノール (東海製薬); 無水エタノール (東豊薬品)
  • 使用上の注意 1.損傷皮膚及び粘膜には使用しないこと。(刺激作用を有するので)。2.副作用(1)過敏症 発疹等の過敏症状があらわれることがあるので、このような場合には使用を中止すること。(2)皮膚 刺激症状があらわれることがあるので、このような症状があらわれた場合には使用を中止すること。3.適用上の注意(1)人体 ア)原液又は濃厚液は刺激作用があるので経口投与しないこと。 イ)眼に入らないように注意すること。入った場合には水でよく洗い流すこと。 ウ)広範囲又は長期間使用する場合には、蒸気の吸入に注意すること。 エ)同一部位に反復使用した場合には、脱脂等による皮膚荒れを起こすことがあるので注意すること。(2)その他本剤は血清、膿汁等の蛋白質を凝固させ、内部にまで浸透しないことがあるので、これらが付着している医療器具等に用いる場合には、十分に洗い落としてから使用すること。(取扱上の注意)(1)金属器具を長時間浸漬する必要がある場合には、腐食を防止するために0.2~1.0%の亜硝酸ナトリウムを添加すること。(2)合成ゴム製品、合成樹脂製品、光学器具、鏡器具、塗装カテーテル等には、変質するものがあるので、このような器具は長時間浸漬しないこと。(3)貯法:遮光した気密容器に入れ、火気を避けて保存する。
  • 説明 Ethyl alcohol, also called ethanol, absolute alcohol, or grain alcohol, is a clear, colorless, flammable liquid with a pleasant odor. It is associated primarily with alcoholic beverages, but it has numerous uses in the chemical industry. The word alcohol is derived from the Arabic word al kuhul, which was a fine powder of the element antimony used as a cosmetic. In Medieval times, the word al kuhul came to be associated with the distilled products known as alcohols. The hydroxyl group, -OH, bonded to a carbon, characterizes alcohols. Ethyl is derived from the root of the two-carbon hydrocarbon ethane.
  • 化学的特性 Ethyl alcohol is a colorless, volatile, flammable liquid with a sweet, fruity odor. The Odor Threshold is 0.1355 ppm.
  • 化学的特性 Ethyl alcohol is a colorless flammable liquid with a typical lower alcohol odor and is miscible in water in all proportions. It is stable and hygroscopic. It is incompatible with strong oxidizing agents, peroxides, acids, acid chlorides, acid anhydrides, alkali metals, ammonia, and moisture. Ethyl alcohol forms explosive mixtures with air. Ethyl alcohol is the most common solvent used in aerosols, cosmetics, pharmaceuticals, alcoholic beverages, vinegar production, and in the chemical synthesis of a large variety of products in different industries. For instance, in the manufacture of plastics, lacquers, polishes, plasticizers, perfumes, adhesives, rubber accelerators, explosives, synthetic resins, nitrocellulose, inks, preservatives, and as a fuel.
  • 化学的特性 In the BP 2009, the term ‘alcohol’; used without other qualification refers to ethanol containing ≥99.5% v/v of C2H6O. The term‘alcohol’, without other qualification, refers to ethanol 95.1–96.9% v/v. Where other strengths are intended, the term ‘alcohol’ or ‘ethanol’is used, followed by the statement of the strength. In the PhEur 6.0, anhydrous ethanol contains not less than 99.5% v/v of C2H6O at 208℃. The term ethanol (96%) is used to describe the material containing water and 95.1–96.9% v/v of C2H6O at 208℃.
  • 天然物の起源 Reported found in apple, apple aroma, apple essence, apple juice, bacon fat, banana, bean, beef fat, beef extract, blackberry, black currant, bread, brussels sprout, cabbage, carrot root, cauliflower, blue cheese, cheddar cheese, Swiss cheese, cocoa bean, cherry, coffee, cream, cucumber, alcoholic beverages and many other sources
  • 来歴 Alcohol is produced naturally from the fermentation of sugars, and it is assumed that prehistoric humans consumed alcohol when eating fermented fruits. The earliest direct evidence of alcohol consumption dates from the Neolithic period 10,000 years ago and consists of stone jugs used for holding alcoholic beverages. Ancient records and art from Egypt, Babylon, Mesopotamia, and other early civilizations indicate the use of alcohol as a beverage, medicine, and ceremonial drink. Records also show that the intoxicating effects of alcohol were known for thousands of years b.c.e. Alcoholic drinks were stored in Egyptian burial tombs, and deities devoted to alcoholic beverages were worshiped by different civilizations. As the human population expanded, alcoholic drinks assumed a prominent role in different cultures; for example, numerous references are made to wine in the Bible. Ancient Islamic alchemists advanced the practice of alcohol production by using distillation techniques. Distilled alcohols began to appear in the Middle Ages and was used in many remedies and medicines. A common practice by alchemists in different regions was the preparation of special liquors and brews with healing power. Aqua vitae (water of life) could refer to brandy, gin, whiskey, wine, or another form of alcoholic depending on the geographic area.
  • 使用 One of the most prominent uses of ethyl alcohol is as a fuel additive and increasingly as a fuel itself. Ethyl alcohol is added to gasoline to increase its oxygen content and octane number. In the United States, the Environmental Protection Agency has mandated that oxygenated fuels be used in certain geographic areas to help meet air quality standards for carbon monoxide, especially in winter. A gasoline blended for this purpose may contain a few percent ethyl alcohol. Gasoline blended with ethyl alcohol is called gasohol. A typical gasohol may contain 90% gasoline and 10% ethanol. Gasohol reduces several common air pollutants including carbon monoxide, carbon dioxide, hydrocarbons, and benzene. Conversely, nitrogen oxides increase with gasohol.
  • 使用 Ethanol is used primarily as a solvent — animportant industrial solvent for resins, lacquers, pharmaceuticals, toilet preparations,and cleaning agents; in the production of rawmaterials for cosmetics, perfumes, drugs, andplasticizers; as an antifreeze; as an automotive fuel additive; and from ancient times, inmaking beverages. Its pathway to the bodysystem is mainly through the consumption ofbeverages. It is formed by the natural fermentation of corn, sugarcane, and other crops.
  • 使用 alcohol (alcohol SD-40; alcohol SDA-40; ethanol; ethyl alcohol) is widely used in the cosmetic industry as an antiseptic as well as a solvent given its strong grease-dissolving abilities. It is often used in a variety of concentrations in skin toners for acne skin, aftershave lotions, perfumes, suntan lotions, and toilet waters. Alcohol dries the skin when used in high concentrations. It is manufactured through the fermentation of starch, sugar, and other carbohydrates.
  • 使用 ethyl alcohol (Etanol) is commonly known as rubbing alcohol. ethyl alcohol is ordinary alcohol and is used medicinally as a topical antiseptic, astringent, and anti-bacterial. At concentrations above 15 percent, it is also a broad-spectrum preservative against bacteria and fungi, and can boost the efficacy of other preservatives in a formulation. Cosmetic companies tend to use alcohol SD-40 in high-grade cosmetic manufacturing as they consider ethanol too strong and too drying for application on the skin. obtained from grain distillation, it can also be synthetically manufactured.
  • 使用 Most ethyl alcohol is used in alcoholic beverages in suitable dilutions. Other uses are as solvent in laboratory and industry, in the manufacture of denatured alcohol, pharmaceuticals (rubbing Compounds, lotions, tonics, colognes), in perfumery, in organic synthesis. Octane booster in gasoline. Pharmaceutic aid (solvent).
  • 使用 Suitable for use in the precipitation of nucleic acids.
  • 定義 ChEBI: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
  • 調製方法 Ethanol is manufactured by the controlled enzymatic fermentation of starch, sugar, or other carbohydrates. A fermented liquid is produced containing about 15% ethanol; ethanol 95% v/v is then obtained by fractional distillation. Ethanol may also be prepared by a number of synthetic methods.
  • 適応症 Intravenous use of ethanol, while once widely employed to inhibit premature labor, is now of historical interest only. Ethanol inhibits oxytocin release from the pituitary and thus indirectly decreases myometrial contractility. Today, 2-adrenomimetics and magnesium sulfate have replaced ethanol for parenteral tocolysis.
  • 適応症 Ethanol is the most widely abused drug in the world. There are more than 10 million alcoholics in the United States alone. Excessive consumption of alcoholic beverages has been linked to as many as half of all traffic accidents, two-thirds of homicides, and three-fourths of suicides, and it is a significant factor in other crimes, in family problems, and in personal and industrial accidents. The annual cost to the American economy has been estimated to exceed $100 billion in lost productivity, medical care, and property damage.
    Alcoholism has been difficult to define because of its complex nature.A person is generally considered an alcoholic, however, when his or her lifestyle is dominated by the procurement and consumption of alcoholic beverages and when this behavior interferes with personal, professional, social, or family relations.
    A light drinker generally is defined as one who consumes an average of one drink or less per day, usually with the evening meal; a moderate drinker is one who has approximately three drinks per day; and a heavy drinker is one who has five or more drinks per day (or in the case of binge drinkers, at least once per week with five or more drinks on each occasion).
  • 定義 A colorless volatile liquid alcohol. Ethanol occurs in intoxicating drinks, in which it is produced by fermentation of a sugar: C6H12O6 → 2C2H5OH + 2CO2 Yeast is used to cause the reaction. At about 15% alcohol concentration (by volume) the reaction stops because the yeast is killed. Higher concentrations of alcohol are produced by distillation. Apart from its use in drinks, alcohol is used as a solvent and to form ethanal. Formerly, the main source was by fermentation of molasses, but now catalytic hydration of ethene is used to manufacture industrial ethanol. See also methylated spirits.
  • 製造方法 There are several approaches to the production of ethanol; mainly ethanol is produced by fermentation.
  • brand name Absolute alcohol;Alcohol aethylicus;Alcool;Avitoin;Banatol;B-tonin;Colfin;Desqyam-x;Duonale-e;Efatin;Equithesin;Hizeneck-d;Honkon-n;Kapsitrin;Keralyt;Levovinizol;Mikrozid;Neotizol;Panoxy;Papette;Piadarn;Polislerol;Protectaderm;Sicol;Sodaphilline;Softa man;Sotracarix;Verucid;Weingeist;Xeracin.
  • 世界保健機関(WHO) Ethanol has been used throughout recorded history both in a medicinal and a social context. It is currently included in pharmaceutical preparations either as an active or inactive ingredient. At pharmacologically active doses ethanol is both a powerful cerebral depressant and a drug of addiction. Its use in pharmaceutical preparations has been severely restricted in several countries and in 1986 the 39th World Health Assembly adopted a resolution to prohibit such use except when ethanol is an essential ingredient which cannot be replaced by an appropriate alternative.
  • Aroma threshold values Detection: 8 to 900 ppb
  • 一般的な説明
    Reagent Alcohol is denatured alcohol that consists of ethanol, isopropyl alcohol and methyl alcohol in the ratio 90:5:5.
  • 反応プロフィール It liberates hydrogen when it reacts withmetal; forms acetaldehyde (toxic, flammable)on catalytic vapor phase dehydrogenation;ethyl ether (flammable) on dehydration withH2SO4 or a heterogeneous catalyst such asalumina, silica, SnCl2, MnCl2, or CuSO4;.
  • 危険性 Classified as a depressant drug. Though it is rapidly oxidized in the body and is therefore noncumulative, ingestion of even moderate amounts causes lowering of inhibitions, often succeeded by dizziness, headache, or nausea. Larger intake causes loss of m
  • 健康ハザード The toxicity of ethanol is much lower thanthat of methanol or propanol. However, theliterature on the subject is vastly greater thanthat of any other alcohol. This is attributableessentially to its use in alcoholic beverages.There are exhaustive reviews on alcohol toxicity and free-radical mechanisms (Nordmannet al. 1987). The health hazard arises primarily from ingestion rather than inhalation. Ingestion of a large dose, 250–500 mL,can be fatal. It affects the central nervoussystem. Symptoms are excitation, intoxication, stupor, hypoglycemia, and coma — thelatter occurring at a blood alcohol contentof 300–400 0 mg/L. It is reported to have atoxic effect on the thyroid gland (Hegeduset al. 1988) and to have an acute hypotensiveaction, reducing the systolic blood pressurein humans (Eisenhofer et al. 1987). Chronicconsumption can cause cirrhosis of the liver.Inhalation of alcohol vapors can result inirritation of the eyes and mucous membranes.This may happen at a high concentrationof 5000–10,000 ppm. Exposure may resultin stupor, fatigue, and sleepiness. There isno report of cirrhosis occurring from inhalation. Chronic exposure to ethanol vapors hasproduced brain damage in mice. The neurotoxicity increases with thiamine deficiency(Phillips 1987). Both acute and chronic dosesof ethanol elevated the lipid peroxidation inrat brain. This was found to be elevated further by vitamin E deficiency, as well as itssupplementation (Nadiger et al. 1988).
    pplementation (Nadiger et al. 1988).The toxicity of ethanol is enhanced in thepresence of compounds such as barbiturates,carbon monoxide, and methyl mercury. Withthe latter compound, ethanol enhanced theretention of mercury in the kidney of ratsand thus increased nephrotoxicity (McNeilet al. 1988). When combined with cocaineand fed to rats, increased maternal and fetaltoxicity was observed (Church et al. 1988).Ethanol is reported to be synergisticallytoxic with caffeine (Pollard 1988) andwith n-butanol and isoamyl alcohol. Priorethanol consumption increased the toxicity of acetaminophen in mice (Carter1987).
  • 燃焼性と爆発性 Ethanol is a flammable liquid (NFPA rating = 3), and its vapor can travel a considerable distance to an ignition source and "flash back." Ethanol vapor forms explosive mixtures with air at concentrations of 4.3 to 19% (by volume). Hazardous gases produced in ethanol fires include carbon monoxide and carbon dioxide. Carbon dioxide or dry chemical extinguishers should be used for ethanol fires.
  • 化学反応性 Reactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
  • 応用例(製薬) Ethanol and aqueous ethanol solutions of various concentrations are widely used in pharmaceutical formulations and cosmetics. Although ethanol is primarily used as a solvent, it is also employed as a disinfectant, and in solutions as an antimicrobial preservative. Topical ethanol solutions are used in the development of transdermal drug delivery systems as penetration enhancers. Ethanol has also been used in the development of transdermal preparations as a co-surfactant.
  • 接触アレルゲン Ethanol is widely used for its solvent and antiseptic properties. It is rather an irritant and sensitization has rarely been reported.
  • Biochem/physiol Actions Positive allosteric modulator of GABAA receptors, and negative allosteric modulator of NMDA glutamate receptors.
  • 作用機序 A great deal of attention has been focused on a class of proteins termed the ligand-gated ion channels as being important to the mechanism of action of alcohol.These integral membrane proteins function as gates or pores that allow the passage of certain ions into and out of neurons upon binding of the appropriate neurotransmitter. This flux of ions largely determines the degree of neuronal activity. Two distinct types of ligand-gated ion channels are particularly sensitive to concentrations of alcohol that produce intoxication and sedation. These are the α-aminobutyric acid (GABA) chloride ionophore and the N-methyl-D-aspartate (NMDA) subtype of glutamate receptor. The GABA–chloride ion channel reduces neuronal activity by hyperpolarizing the neurons, while activation of the NMDA receptor causes neuronal depolarization or excitation. Alcohol has been shown to increase chloride flux through the GABAA receptor and reduce calcium flux through the NMDA receptor. These actions result in powerful suppression of nerve cell activity, which is consistent with the depressant actions of alcohol in the brain.
  • 臨床応用 Generally, no treatment is required for acute ethanol intoxication. Allowing the individual to sleep off the effects of ethanol ingestion is the usual procedure. Hangovers are treated similarly; that is, no effective remedy exists for a hangover, except for controlling the amount of ethanol consumed. Sometimes ethanol overdose is a medical emergency. For example, prompt treatment is required if the patient is in danger of dying of respiratory arrest, is comatose, has dilated pupils, is hypothermic, or displays tachycardia.
    Treatment for severe ethanol overdose is generally supportive. Increased intracranial pressure can be relieved by intravenous administration of hypertonic mannitol. Hemodialysis can accelerate the removal of ethanol from the body. Stimulants of ethanol metabolism, such as fructose, are not sufficiently effective, and use of analeptics is not recommended because of the possibility of precipitating convulsions.
    The immediate concern in the treatment of alcoholics is detoxification and management of the ethanol withdrawal syndrome. Another pharmacological approach is the use of anticraving drugs, for example serotonin uptake inhibitors,dopaminergic agonists, and opioid antagonists.The only treatment that has shown considerable promise is one that uses the opioid antagonist naltrexone.
  • 副作用 Acute Ethanol Intoxication and Hangover
    Ethanol intoxication is probably the best-known form of drug toxicity. Intoxicated individuals are a threat to themselves and others, particularly if they attempt to drive or operate machinery. Although death can result from ethanol overdose, usually the patient lapses into a coma before ingesting lethal quantities. Ethanol intoxication is sometimes mistakenly diagnosed as diabetic coma, schizophrenia, overdosage of other CNS depressant drugs, or skull fracture. An additional feature commonly associated with excessive ethanol consumption is difficulty in regulating body temperature. Hypothermia frequently results, with body temperature falling toward that of the ambient environment. This problem can be particularly severe in the elderly, who normally have difficulty regulating their body temperature.
    One of the consequences of ethanol intoxication is the hangover, a condition characterized by headache, nausea, sweating, and tremor. Although unpleasant, a hangover is not dangerous, even though the person having one may feel otherwise.
  • 安全性プロファイル Confirmed human carcinogen for ingestion of beverage alcohol. Experimental tumorigenic and teratogenic data. Moderately toxic to humans by ingestion. Moderately toxic experimentally by intravenous and intraperitoneal routes. Mildly toxic by inhalation and skin contact. Human systemic effects by ingestion and subcutaneous routes: sleep disorders, hallucinations, dtstorted perceptions, convulsions, motor activity changes, ataxia, coma, antipsychotic,headache, pulmonary changes, alteration in gastric secretion, nausea or vomiting, other gastrointestinal changes, menstrual cycle changes, and body temperature decrease. Can also cause glandular effects in humans. Human reproductive effects by ingestion, intravenous, and intrauterine routes: changes in female fertility index. Effects on newborn include: changes in Apgar score, neonatal measures or effects, and drug dependence. Experimental reproductive effects. Human mutation data reported. An eye and skin irritant. The systemic effect of ethanol differs from that of methanol. Ethanol is rapidly oxidtzed in the body to carbon dtoxide and water, and, in contrast to methanol, no cumulative effect occurs. Though ethanol possesses narcotic properties, concentrations sufficient to produce this effect are not reached in industry. Concentrations below 1000 pprn usually produce no signs of intoxication. Exposure to concentrations over 1000 pprn may cause headache, irritation of the eyes, nose, and throat, and, if continued for an hour, drowsiness and lassitude, loss of appetite, and inability to concentrate. There is no concrete evidence that repeated exposure to ethanol vapor results in cirrhosis of the liver. Ingestion of large doses can cause alcohol poisoning. Repeated ingestions can lead to alcoholism. It is a central nervous system depressant.Flammable liquid when exposed to heat or flame; can react vigorously with oxidizers. To fight fire, use alcohol foam, CO2, dry chemical. Explosive reaction with the oxidized coating around potassium metal. Ignites and then explodes on contact with acetic anhydride + sodum hydrogen sulfate. Reacts violently with acetyl bromide (evolves hydrogen bromide), dichloromethane + sulfuric acid + nitrate or nitrite, disulfuryl difluoride, tetrachlorosilane + water, and strong oxidants. Ignites on contact with disulfuric acid + nitric acid, phosphorus(IⅡ) oxide, platinum, potassium tert-butoxide + acids. Forms explosive products in reaction with ammonia + silver nitrate (forms silver nitride and silver fulminate), magnesium perchlorate (forms ethyl perchlorate), nitric acid + silver (forms silver fulminate), silver nitrate (forms ethyl nitrate), silverp) oxide + ammonia or hydrazine (forms silver nitride and silver fulminate), sodum (evolves hydrogen gas). Incompatible with acetyl chloride, BrF5, Ca(OCl)2, ClO3, Cr03, Cr(OCl)2, (cyanuric acid + H20), H202, HNO3, (H202 + H2SO4), (I + CH3OH + HgO), wn(ClO4)2 + 2,2-dimethoxy propane], Hg(NO3)2, HClO4, perchlorates, (H2SO4 + permanganates), HMn04, KO2, KOC(CH3)3, AgClO4, NaH3N2, uo2(clO4)2
  • 安全性 Ethanol and aqueous ethanol solutions are widely used in a variety of pharmaceutical formulations and cosmetics. It is also consumed in alcoholic beverages.
    Ethanol is rapidly absorbed from the gastrointestinal tract and the vapor may be absorbed through the lungs; it is metabolized, mainly in the liver, to acetaldehyde, which is further oxidized to acetate.
    Ethanol is a central nervous system depressant and ingestion of low to moderate quantities can lead to symptoms of intoxication including muscle incoordination, visual impairment, slurred speech, etc. Ingestion of higher concentrations may cause depression of medullary action, lethargy, amnesia, hypothermia, hypoglycemia, stupor, coma, respiratory depression, and cardiovascular collapse. The lethal human blood-alcohol concentration is generally estimated to be 400–500 mg/100 mL.
    Although symptoms of ethanol intoxication are usually encountered following deliberate consumption of ethanol-containing beverages, many pharmaceutical products contain ethanol as a solvent, which, if ingested in sufficiently large quantities, may cause adverse symptoms of intoxication. In the USA, the maximum quantity of alcohol included in OTC medicines is 10% v/v for products labeled for use by people of 12 years of age and older, 5% v/v for products intended for use by children aged 6–12 years of age, and 0.5% v/v for products for use by children under 6 years of age.
    Parenteral products containing up to 50% of alcohol (ethanol 95 or 96% v/v) have been formulated. However, such concentrations can produce pain on intramuscular injection and lower concentrations such as 5–10% v/v are preferred. Subcutaneous injection of alcohol (ethanol 95% v/v) similarly causes considerable pain followed by anesthesia. If injections are made close to nerves, neuritis and nerve degeneration may occur. This effect is used therapeutically to cause anesthesia in cases of severe pain, although the practice of using alcohol in nerve blocks is controversial. Doses of 1mL of absolute alcohol have been used for this purpose.
    Preparations containing more than 50% v/v alcohol may cause skin irritation when applied topically.
    LD50 (mouse, IP): 0.93 g/kg
    LD50 (mouse, IV): 1.97 g/kg
    LD50 (mouse, oral): 3.45 g/kg
    LD50 (mouse, SC): 8.29 g/kg
    LD50 (rat, IP): 3.75 g/kg
    LD50 (rat, IV): 1.44 g/kg
    LD50 (rat, oral): 7.06 g/kg
  • 職業ばく露 Ethyl alcohol is used, topical antiinfective agent; solvent to make beverages; in the chemical synthesis of a wide variety of compounds, such as acetaldehyde, ethyl ether, ethyl chloride, and butadiene. It is a solvent or processing agent in the manufacture of pharmaceuticals; plastics, lacquers, polishes, plasticizers, perfumes, cosmetics, rubber accelerators; explosives, synthetic resins; nitrocellulose, adhesives, inks, and preservatives. It is also used as an antifreeze and as a fuel. It is an intermediate in the manufacture of many drugs and pesticides.
  • Carcinogenicity In 1987, the International Agency for Research on Cancer (IARC) evaluated the cancer data on ethanol and alcoholic beverages in humans and animals . The IARC concluded that there was inadequate evidence for the carcinogenicity of ethanol and of alcoholic beverages in experimental animals, but there was sufficient evidence for the carcinogenicity of alcoholic beverages in humans. The IARC classified alcoholic beverages as a Group 1 carcinogen based on the occurrence of malignant tumors of the oral cavity, pharynx, larynx, esophagus, and liver that have been causally related to the consumption of alcoholic beverages.
  • 環境運命予測 If released to the environment from natural or anthropogenic sources, ethanol will preferentially partition to the soil, water, and air. Bioconcentration and bioaccumulation potential is anticipated to be low based upon the estimated bioconcentration factor and experimental octanol/water partition coefficient. If released into water, ethanol’s half-life is less than 10 days. The half-life upon release to air is less than 5 days, where wet deposition removal predominates. Biodegradation and volatilization are expected to be important fate and transport processes for ethanol.
  • 貯蔵 Ethyl alcohol should be protected from physical damage. It should be kept stored in a cool, dry, well-ventilated location, away from any area where the fi re hazard may be acute. Outside or detached storage is preferred. Separate from incompatibles. Containers should be bonded and grounded for transfer to avoid static sparks. The storage and use areas should be free from smoking areas.
  • 輸送方法 UN1170 Ethyl alcohol or Ethanol or Ethanol solutions or Ethyl alcohol solutions, Hazard Class: 3; Labels: 3-Flammable liquid.
  • 純化方法 Usual impurities of fermentation alcohol are fusel oils (mainly higher alcohols, especially pentanols), aldehydes, esters, ketones and water. With synthetic alcohol, likely impurities are water, aldehydes, aliphatic esters, acetone and diethyl ether. Traces of *benzene are present in ethanol that has been dehydrated by azeotropic distillation with *benzene. Anhydrous ethanol is very hygroscopic. Water (down to 0.05%) can be detected by formation of a voluminous precipitate when aluminium ethoxide in *benzene is added to a test portion, Rectified spirit (95% ethanol) is converted to absolute (99.5%) ethanol by refluxing with freshly ignited CaO (250g/L) for 6hours, standing overnight and distilling with precautions to exclude moisture. Numerous methods are available for further drying of absolute ethanol for making “Super dry ethanol”. Lund and Bjerrum [Chem Ber 64 210 1931] used reaction with magnesium ethoxide, prepared by placing 5g of clean dry magnesium turnings and 0.5g of iodine (or a few drops of CCl4), to activate the Mg, in a 2L flask, followed by 50-75 mL of absolute ethanol, and warming the mixture until a vigorous reaction occurs. When this subsides, heating is continued until all the magnesium is converted to magnesium ethoxide. Up to 1L of ethanol is then added and, after an hour's reflux, it is distilled off. The water content should be below 0.05%. Walden, Ulich and Laun [Z Phys Chem 114 275 1925] used amalgamated aluminium chips, prepared by degreasing aluminium chips (by washing with Et2O and drying in a vacuum to remove grease from machining the Al), treating with alkali until hydrogen evolved vigorously, washing with H2O until the washings were weakly alkaline and then stirring with 1% HgCl2 solution. After 2minutes, the chips were washed quickly with H2O, then alcohol, then ether, and dried with filter paper. (The amalgam became warm.) These chips were added to the ethanol, which was then gently warmed for several hours until evolution of hydrogen ceased. The alcohol was distilled and aspirated for some time with pure dry air. Smith [J Chem Soc 1288 1927] reacted 1L of absolute ethanol in a 2L flask with 7g of clean dry sodium, and added 25g of pure ethyl succinate (27g of pure ethyl phthalate was an alternative), and refluxed the mixture for 2hours in a system protected from moisture, and then distilled the ethanol. A modification used 40g of ethyl formate instead, so that sodium formate separated out and, during reflux, the excess of ethyl formate decomposed to CO and ethanol. Drying agents suitable for use with ethanol include Linde type 4A molecular sieves, calcium metal, and CaH2. The calcium hydride (2g) is crushed to a powder and dissolved in 100mL absolute ethanol by gently boiling. About 70mL of the ethanol are distilled off to remove any dissolved gases before the remainder is poured into 1L of ca 99.9% ethanol in a still, where it is boiled under reflux for 20hours, while a slow stream of pure, dry hydrogen (better use nitrogen or Ar) is passed through. It is then distilled [Rüber Z Elektrochem 29 334 1923]. If calcium is used for drying, about ten times the theoretical amount should be used, and traces of ammonia (from some calcium nitride in the Ca metal) would be removed by passing dry air into the vapour during reflux. Ethanol can be freed from traces of basic materials by distillation from a little 2,4,6-trinitrobenzoic acid or sulfanilic acid. *Benzene can be removed by fractional distillation after adding a little water (the *benzene/water/ethanol azeotrope distils at 64.9o), the alcohol is then re-dried using one of the methods described above. Alternatively, careful fractional distillation can separate *benzene as the *benzene/ethanol azeotrope (b 68.2o). Aldehydes can be removed from ethanol by digesting with 8-10g of dissolved KOH and 5-10g of aluminium or zinc per L, followed by distillation. Another method is to heat under reflux with KOH (20g/L) and AgNO3 (10g/L) or to add 2.5-3g of lead acetate in 5mL of water to 1L of ethanol, followed (slowly and without stirring) by 5g of KOH in 25mL of ethanol: after 1hour the flask is shaken thoroughly, then set aside overnight before filtering and distilling. The residual water can be removed by standing the distillate over activated aluminium amalgam for 1 week, then filtering and distilling. Distillation of ethanol from Raney nickel eliminates catalyst poisons. Other purification procedures include pre-treatment with conc H2SO4 (3mL/L) to eliminate amines, and with KMnO4 to oxidise aldehydes, followed by refluxing with KOH to resinify aldehydes, and distilling to remove traces of H3PO4 and other acidic impurities after passage through silica gel, and drying over CaSO4. Water can be removed by azeotropic distillation with dichloromethane (azeotrope boils at 38.1o and contains 1.8% water) or 2,2,4-trimethylpentane. [Beilstein 1 IV 1289.] Rapid purification: Place degreased Mg turnings (grease from machining the turnings is removed by washing with dry EtOH then Et2O, and drying in a vacuum) (5g) in a dry 2L round bottomed flask fitted with a reflux condenser (protect from air with a drying tube filled with CaCl2 or KOH pellets) and flush with dry N2. Then add iodine crystals (0.5g) and gently warm the flask until iodine vapour is formed and coats the turnings. Cool, then add EtOH (50mL) and carefully heat to reflux until the iodine disappears. Cool again then add more EtOH (to 1L) and reflux under N2 for several hours. Distil and store over 3A molecular sieves (pre-heated at
  • Toxicity evaluation Upon acute exposure ethanol is a central nervous system (CNS) depressant that initially and selectively depresses some of the most active portions of the brain (reticular activity system and cortex). The mechanism of action most likely involves interference with ion transport at the axonal cell membrane rather than at the synapse, similar to the action of other anesthetic agents. Ethanol can bind directly to the gamma-aminobutyric acid receptor in the CNS and cause sedative effects. Ethanol may also have direct effects on cardiac muscle, thyroid tissue, and hepatic tissue.
    Chronic and excessive ethanol ingestion has been associated with a wide range of adverse effects. At the cellular level these effects can be attributable to metabolic intermediates. Ethanol is metabolized differently at low and high concentrations. At low ethanol blood levels ethanol is metabolized very efficiently by alcohol dehydrogenase to acetaldehyde and then by aldehyde dehydrogenase to acetate producing nicotinamide adenine dinucleotide (NADH) in both reactions.
    Chronic high ethanol intake induces the cytochrome P450 mediated MEOS, which can be predominant. Under these conditions ethanol is metabolized to acetaldehyde without reducing NADH. The MEOS pathway utilizes nicotinamide adenine dinucleotide phosphate thus producing an oxidative environment, which decreases the reducing equivalents present in the cell, increasing oxidative stress. This pathway has been associated with the release of highly reactive oxygen species in addition to acetaldehyde, which contributes to the hepatic damage observed in chronic alcohol abuse.
    Acetaldehyde has been implicated as one significant contributor to the toxicity observed in chronic ethanol overexposure (see Acetaldehyde). Acetaldehyde is highly reactive and can interact with DNA and proteins to form stable adducts. These DNA adducts may induce mutations, although there is an absence of direct evidence that they are in fact the initiators of cancers associated with alcohol ingestion. Acetaldehyde and malondialdehyde, a product of ethanol-induced lipid peroxidation, can form protein adducts which have been found in the serum of alcoholics and rats fed ethanol. These adducts are capable of eliciting an immune response believed to be important in the inflammatory processes observed in alcoholic liver disease and possibly neurotoxicity.
  • 不和合性 In acidic conditions, ethanol solutions may react vigorously with oxidizing materials. Mixtures with alkali may darken in color owing to a reaction with residual amounts of aldehyde. Organic salts or acacia may be precipitated from aqueous solutions or dispersions. Ethanol solutions are also incompatible with aluminum containers and may interact with some drugs.
  • 廃棄物の処理 Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.
  • 予防処置 During handling of ethyl alcohol, workers should use chemical-resistant shields, monogoggles, proper gloves, laboratory coat/apron, and protective equipment as required. Workers and the workplace should have adequate ventilation vent hoods, class b extinguisher. Workers should avoid sources of heat, sparks, or flames. Waste disposal and spill should be collected in suitable containers or absorbed on a suitable absorbent material for subsequent disposal. Waste material should be disposed of in an approved incinerator or in a designated landfi ll site, in compliance with all federal, provincial, and local government regulations.
  • 規制状況(Regulatory Status) Included in the FDA Inactive Ingredients Database (dental preparations; inhalations; IM, IV, and SC injections; nasal and ophthalmic preparations; oral capsules, solutions, suspensions, syrups, and tablets; rectal, topical, and transdermal preparations). Included in the Canadian List of Acceptable Non-medicinal Ingredients. Included in nonparenteral and parenteral medicines licensed in the UK.
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  • ALCOHOL DENAT.
  • ETHYL ALCOHOL, ANHYDROUS, 200 PROOF, 99.5+%
  • ETHYL ALCOHOL, REAGENT, ANHYDROUS, DENAT URED
  • ETHANOL, DENATURATED 'S15'
  • ETHANOL CONTROL-H
  • ETHANOL 200 PROOF HPLC/SPECTROPHOTOME&
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  • TOYOPEARL SUPER Q-650M, 250ML
  • ETHANOL, ABSOLUTE, `A15 O`
  • ETHANOL 96 VOL.% REINST DAB
  • Ethanol min. 99,9 %
  • ETHANOL SOLUTION 70% IN WATER TECHNICAL
  • ETHANOL, DENAT. WITH 1% TOLUENE, 'F25 T'
  • ETHYL ALCOHOL, REAGENT, DENATURED, SPECT ROPHOTOMETRIC GRADE
  • ETHANOL 200 PROOF USP/NF
  • ETHANOL, 4X25 ML
  • ETHANOL (A15 ALKOHOL ABSOLUTUS) 5 L
  • ETHANOL, FOR LUMINESCENCE
  • ETHANOL, DENAT. WITH 4.8% ISOPROPANOL, ' F25 ISO'
  • POTASSIUM BROMIDE SPECTRANAL
  • ETHYL ALCOHOL, REAGENT, DENATURED, HPLC GRADE
  • ETHANOL, FOR HPLC, GRADIENT GRADE
  • SODIUM HYDRIDE 60% DISPERSION IN MINERA
  • Ethanol, ACS, absolute, 'A15 O'
  • HYDRANAL-TITRATION REAGENT FOR TESTKIT
  • ETHANOL OEKANAL.
  • ETHANOLIC WASH
  • ETHANOL ABSOLUTE PURISS. P.A.,REAG. ACS, REAG. ISO, REAG. PH. EUR.
  • ETHANOL ABSOLUTE EXTRA PURE
  • ETHANOL, ABS., DENATURATED WITH 2% 2-BU- TANONE, 'A15 K'
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  • 消毒用エタプロコール-U
  • エタノ-ル
  • エタノール CRM4001-A
  • エタノール(99.5)
  • エタノール(脱水)
  • エタノル
  • 変性アルコール
  • 局方エタノール
  • 局方無水エタノール
  • 局方消毒エタノール
  • 無水エタノール
  • エタノール CRM4001‐B
  • エタノール(95)
  • エタノール標準原液
  • 無水エタノール(UE)
  • エタノール (95%)エチルアルコール (95%)
  • エタノール (99.5%)エチルアルコール (99.5%)
  • エタノール (99.5)
  • エタノール ABSOLUTE エタノール,DENATURATED WITH 4.8% メタノール,A15 METHYL 1 ,≥99.8% (BASED ON DENATURANT-FREE SUBSTANCE)
  • エタノール ABSOLUTE,≥99.8% (GC)
  • エタノール ABSOLUTE,DENATURATED WITH 0.5-1.5 VOL.% 2-ブタノン AND APPROX. 0.001% BITREX (GC),≥98% (GC)
  • エタノール ABSOLUTE,REAG. ISO,REAG. PH. EUR.,≥99.8% (GC),LIQUID (CLEAR,COLORLESS)
  • エタノール PURISS. P.A.,ABSOLUTE,≥99.8% (GC)
  • エタノール PURISS.,MEETS ANALYTICAL SPECIFICATION OF PH.EUR.,BP,96.0-97.2%
  • エタノール PURUM,FINE SPIRIT,WITHOUT ADDITIVE,F25 O1,~96%
  • エタノール SOLUTION TESTED ACCORDING TO PH.HELV.,70 % (V/V) IN H2O
  • エタノール,ABSOLUTE,DENATURATED WITH 1%
  • エチルアルコール,PURE 200 PROOF,ACS REAGENT,≥99.5%
  • エチルアルコール,PURE 200 PROOF,FOR MOLECULAR BIOLOGY
  • エチルアルコール,PURE 200 PROOF,HPLC/SPECTROPHOTOMETRIC GRADE
  • エチルアルコール,PURE 200 PROOF,MEETS USP TESTING SPECIFICATIONS
  • IPA変性アルコール 95%
  • IPA変性アルコール 99%
  • IPA変性エタノー
  • エチルアルコール(99.5)
  • メタ変性アルコール 95%
  • メタ変性アルコール 99%
  • メタ変性エタノー
  • エタノール(95V/V%)
  • エタノール(99.5V/V%)
  • エタノール (95)
  • エタノール「製造専用」
  • エタノールスプレー
  • 組織脱水溶液 99
  • エタノール 溶液
  • 無水エタノール (JP17)
  • エタノール,エチルアルコール
  • 溶媒
  • 殺菌薬
  • 外皮作用薬
  • 中枢抑制薬