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N-NITROSO-N-ETHYLUREA

CAS No.759-73-9
Chemical Name:N-NITROSO-N-ETHYLUREA
CBNumber:CB8733913
Molecular Formula:C3H7N3O2
Formula Weight:117.11
MOL File:759-73-9.mol

N-NITROSO-N-ETHYLUREA Property

Melting point 103-1040C (dec)
Boiling point 182℃
Density 1.35
refractive index 1.4900 (estimate)
Flash point 64℃
storage temp. -20°C
solubility DMSO (Soluble), Methanol (Sparingly)
form Semi-Solid to Low-Melting Solid
pka 12.32±0.50(Predicted)
color Off-White to Red
Water Solubility 12.83g/L(room temperature)
Specific Activity 9-13nmol/min·mg
Stability Unstable at RT, Contains approximately 40% Water, 2.0% Acetic Acid to stabilize
CAS DataBase Reference 759-73-9(CAS DataBase Reference)
EWG's Food Scores 2
FDA UNII P8M1T4190R
Proposition 65 List N-Nitroso-N-ethylurea
IARC 2A (Vol. 17, Sup 7) 1987
EPA Substance Registry System N-Nitroso-N-ethylurea (759-73-9)
UNSPSC Code 51111800
NACRES NA.32

Safety

Hazard Codes :T
Risk Statements :45-46-61-20/21/22
Safety Statements :53-22-36/37/39-45
RIDADR :UN 2811 6.1/PG 3
WGK Germany :3
RTECS :YT3150000
HazardClass :6.1(b)
PackingGroup :III
Hazardous Substances Data :759-73-9(Hazardous Substances Data)
Toxicity :LD50 i.v. in rats: 240 mg/kg (Druckrey)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordDanger
Hazard statements H301-H312+H332-H350-H360
Precautionary statements P201-P202-P280-P301+P310-P302+P352+P312-P304+P340+P312

N-NITROSO-N-ETHYLUREA Price More Price(3)

Brand: Sigma-Aldrich(India)
Product number: N8509
Product name : N-Nitroso-N-ethylurea
Purity: Bulk package
Packaging: 5G
Price: ₹9937.35
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: N8509
Product name : N-Nitroso-N-ethylurea
Purity: Bulk package
Packaging: 25G
Price: ₹35376.1
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: N3385
Product name : N-Nitroso-N-ethylurea
Purity: ISOPAC?
Packaging: 1G
Price: ₹4763
Updated: 2022/06/14
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N-NITROSO-N-ETHYLUREA Chemical Properties,Usage,Production

Chemical Properties N-Nitroso-N-ethyl urea is a pale yellow, crystalline powder; freezing/melting point=103－104°C (decomposes). Hazard identification (based on NFPA-704 M Rating System): Health 2; flammability 1; reactivity 0?. Soluble in water; hydrolysis produces explosive gas.
Chemical Properties Orange Paste
Uses N-Nitroso-N-ethylurea has been used as a mutation-inducing agent.
Uses A precursor of Diazoethane
Uses Experimentally as mutagen; ethylating agent.
Definition ChEBI: A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by ethyl and nitroso groups.
General Description Yellow-pink crystals or off-white powder. Sensitive to light.
Air & Water Reactions Water soluble. Sensitive to moisture--stability in aqueous solutions depends on pH.
Reactivity Profile N-NITROSO-N-ETHYLUREA is highly reactive. Sensitive to moisture and light. Its stability in aqueous solutions is pH-dependent. Incompatible with water and nucleophilic reagents. Alkaline hydrolysis produces a highly explosive gas. .
Hazard Tumorigen, carcinogen, neoplastigen; teratogen; poison; toxic.
Health Hazard ACUTE/CHRONIC HAZARDS: N-NITROSO-N-ETHYLUREA is extremely unstable at high pH. It will decompose to extremely unstable decomposition products if acidic conditions are not maintained. When heated to decomposition it emits toxic fumes of nitrogen oxides. Decomposition products may be explosive.
Fire Hazard Flash point data for N-NITROSO-N-ETHYLUREA are not available; however, N-NITROSO-N-ETHYLUREA is probably combustible.
Biochem/physiol Actions DNA alkylating agent that is carcinogenic in many animal species. Induces benign and malignant tumors of numerous types, including the nervous tissue, stomach, esophagus, pancreas, respiratory tract, intestine, lymphoreticular tissues, skin, and kidney.
Safety Profile Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by ingestion, subcutaneous, intraperitoneal, and intravenous routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.
Potential Exposure Used as a chemical intermediate for dyes and pharmaceuticals; a polymerization inhibitor during the manufacture of vinyl monomers such as styrene; a precursor of diazoethane; accelerator for rubber vulcanization.
Carcinogenicity N-Nitroso-N-ethylurea is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Shipping Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard Class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.
Incompatibilities N-nitroso-N-ethylurea is highly reactive. Sensitive to moisture and light. Its stability in aqueous solutions is pH-dependent. Incompatible with water and nucleophilic reagents. Alkaline hydrolysis produces a highly explosive gas. This compound is extremely unstable at high pH. It will decompose to extremely unstable decomposition products if acidic conditions are not maintained. Nitrated organics range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction. Reaction with
Waste Disposal Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.