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Ranimustine

Ranimustine Structure
Ranimustine
  • CAS No.58994-96-0
  • Chemical Name:Ranimustine
  • CBNumber:CB4269380
  • Molecular Formula:C10H18ClN3O7
  • Formula Weight:327.72
  • MOL File:58994-96-0.mol
Ranimustine Property
  • Melting point 111-112°
  • alpha D20 +93.2° (c = 0.5 in methanol) (Kimura); D25 +73.2° (c = 0.3 in methanol) (Kimura, Sekine)
  • Density 1.69±0.1 g/cm3(Predicted)
  • solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
  • form Solid
  • pka 10.59±0.46(Predicted)
  • color Off-White to Pale Yellow
  • CAS DataBase Reference 58994-96-0(CAS DataBase Reference)
  • FDA UNII RYH2T97J77
  • NCI Drug Dictionary ranimustine
  • ATC code L01AD07
Safety
  • Toxicity :LD50 in male rats (mg/kg): 42 i.p., 42 i.v., 50 orally (Kimura)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Ranimustine Chemical Properties,Usage,Production

  • Description Ranimustine, a new nitrosourea derivative, is a water soluble antitumor agent with low hematological toxicity and diabetogenic effect. It is reportedly effective in the treatment of hematologic malignancies, especially the myeloproliferative disorders.
  • Originator Tokyo Tanabe (Japan)
  • Uses Glucocorticoid with low systemic absorption anti-inflammatory agent
  • Definition ChEBI: Ranimustine is an organic molecular entity.
  • brand name Cymerine
Ranimustine Preparation Products And Raw materials
Raw materials
Preparation Products
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Ranimustine Spectrum
58994-96-0, RanimustineRelated Search:
  • 抑制剂
  • 药物
  • 烷化剂抗肿瘤药物
  • 抗肿瘤药
  • C10H18ClN3O7
  • 化合物 RANIMUSTINE
  • 雷诺氮芥
  • 甲基-6-[[[(2-氯乙基)亚硝氨基]碳酰]氨基]-6-脱氧-Α-D-吡喃葡糖苷
  • 1-(2-氯乙基)-1-亚硝基-3-[[(2R,3S,4S,5R,6S)-3,4,5-三羟基-6-甲氧基-氧杂己环-2-基]甲基]脲
  • 雷莫司汀
  • 58994-96-0
  • Ranimustine USP/EP/BP
  • α-D-Glucopyranoside, methyl 6-[[[(2-chloroethyl)nitrosoamino]carbonyl]amino]-6-deoxy-
  • RCL L16,919-6
  • RANIMUSTINE
  • NSC 270516
  • CyMerine
  • Methyl 6-[3-(2-chloroethyl)-3-nitrosoureido]-6-deoxy-α-D-glucopyranoside
  • Thymerin
  • Ranomustine
  • NSC-0270516
  • Methyl 6-[[[(2-chloroethyl)nitrosoamino]carbonyl]amino]-6-deoxy-α-D-glucopyranoside
  • MCNU
  • Cymerin
  • 1-(2-chloroethyl)-1-nitroso-3-[[(2r,3s,4s,5r,6s)-3,4,5-trihydroxy-6-methoxy-oxan-2-yl]methyl]urea