ChemicalBook > CAS DataBase List > Fotemustine
Fotemustine
Fotemustine
- CAS No.92118-27-9
- Chemical Name:Fotemustine
- CBNumber:CB9666315
- Molecular Formula:C9H19ClN3O5P
- Formula Weight:315.69
- MOL File:92118-27-9.mol
Fotemustine Property
- Melting point 85°
- Density 1.37±0.1 g/cm3(Predicted)
- storage temp. 2-8°C
- solubility H2O: ≥1mg/mL
- form powder
- pka 9.47±0.46(Predicted)
- color light yellow
- CAS DataBase Reference 92118-27-9(CAS DataBase Reference)
- EWG's Food Scores 1
- NCI Dictionary of Cancer Terms fotemustine
- FDA UNII GQ7JL9P5I2
- NCI Drug Dictionary fotemustine
- ATC code L01AD05
Safety
- Hazard Codes :Xn
- Risk Statements :40
- Safety Statements :36/37
- WGK Germany :3
- Hazardous Substances Data :92118-27-9(Hazardous Substances Data)
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H351
- Precautionary statements P281
Fotemustine Chemical Properties,Usage,Production
- Description Fotemustine is a new nitrosourea reportedly effective in the treatment of disseminated malignant melanoma, with only mild hematological toxicity. Response rate is generally lower in patients with colonic, breast, head and neck cancer.
- Originator Servier (France)
- Uses Fotemustine is used in patients malignant gliomas to improve the efficacy of radiotherapy. Used in the treatment of glioblastomas.
- Definition ChEBI: Diethyl (1-{[(2-chloroethyl)(nitroso)carbamoyl]amino}ethyl)phosphonate is a member of the class of N-nitrosoureas that is ethyl diethylphosphonate in the hydrogen at position 1 of the ethyl group attached to the phosphorus has been replaced by a [(2-chloroethyl)(nitroso)carbamoyl]amino group. It is an organic phosphonate, a member of N-nitrosoureas and an organochlorine compound.
- brand name Muphoran
Fotemustine Preparation Products And Raw materials
Raw materials
Preparation Products
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92118-27-9, FotemustineRelated Search:
- Triethyl phosphite Bendamustine hydrochloride Diethyl phosphite DIETHYL ETHYLPHOSPHONATE Triethyl phosphate Bendamustine Ethyl dichlorophosphate Tris(2-chloroethyl) phosphate N-NITROSO-N-ETHYLUREA N-Nitrocarbamide 1-Methyl-1-nitrosourea Chlorine ETHYLPHOSPHONIC ACID DIETHYL PHOSPHATE Chlormethine (AMINOMETHYL)PHOSPHONIC ACID HYDROCHLORIDE DIETHYL N-FORMYL-AMINOMETHYL PHOSPHONATE 1-(2-chloroethyl)-1-nitrosourea
- 原料药中间体
- 医药原料
- 药物
- 抗肿瘤药
- 烷化剂抗肿瘤药物
- C9H19ClN3O5P
- 化合物 T21305
- [1-[[[(2-氯乙基)亚硝基胺]羰基]氨基]乙基]膦酸二乙酯
- 福莫司汀
- 福泰氮芥
- 1-[3-(2-氯乙基)-3-亚硝基脲]-乙基磷酸二乙酯
- 92118-27-9
- Fotemustine USP/EP/BP
- Fotemustene
- P-[1-[[[(2-Chloroethyl)nitrosoamino]carbonyl]amino]ethyl]-phosphonic acid diethyl ester
- Mustophorane
- diethyl [(1S)-1-{[N-(2-chloroethyl)-N'-oxohydrazinecarbonyl]aMino}ethyl]phosphonate
- Phosphonic acid, (1-((((2-chloroethyl)nitrosoamino)carbonyl)amino)ethyl)-, diethyl ester
- Fotemustinum [latin]
- Fotemustinum
- Fotemustina [spanish]
- Fotemustina
- Diethyl-1-(3-(2-chloroethyl)-3-nitrosoureido)ethylphosphonate
- Ccris 6337
- (+-)-Diethyl (1-(3-(2-chloroethyl)-3-nitrosoureido)ethyl)phosphonate
- [1-[[[(2-Chloroethyl)nitrosoamino]carbonyl]amino]ethyl]phosphonic acid diethyl ester
- [1-[[[(2-Chloroethyl)nitlx~amino]carbonyl]amino]ethyl]phosphonic acid diethyl ester
- Phosphonic acid, P-[1-[[[(2-chloroethyl)nitrosoamino]carbonyl]amino]ethyl]-, diethyl ester
- S-10036
- Muphoran
- Fotemustin
- FOTEMUSTINE
- 1-(2-chloroethyl)-3-(1-diethoxyphosphorylethyl)-1-nitrosourea