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17alpha-Ethynyl-19-nortestosterone 17-heptanoate

17alpha-Ethynyl-19-nortestosterone 17-heptanoate Structure
17alpha-Ethynyl-19-nortestosterone 17-heptanoate
  • CAS No.3836-23-5
  • Chemical Name:17alpha-Ethynyl-19-nortestosterone 17-heptanoate
  • CBNumber:CB8849821
  • Molecular Formula:C27H38O3
  • Formula Weight:410.59
  • MOL File:3836-23-5.mol
17alpha-Ethynyl-19-nortestosterone 17-heptanoate Property
  • Melting point: :69.5°C
  • Boiling point: :470.54°C (rough estimate)
  • Density  :1.0736 (rough estimate)
  • refractive index  :1.4700 (estimate)
  • color  :Crystals from pet ether
  • CAS DataBase Reference :3836-23-5(CAS DataBase Reference)
  • FDA UNII :HY3S2K0J0F
Safety
  • Toxicity :TDLo vn-wmn: 4 mg/kg:EYE ADVPB4 8,103,72
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

17alpha-Ethynyl-19-nortestosterone 17-heptanoate Chemical Properties,Usage,Production

  • Originator Norigest,Schering
  • Manufacturing Process 1 g 17-ethinyl-19-nor-testosteron was refluxed with 5 ml of enanthic acid anhydride on an oil bath at temperature 180°C 17 hours. Then the reaction mixture was distilled with water steam to the full disappearence of smell of enantic acid. After that it was washed with 2 N sodium hydroxide and finally with water to neutral, dried over sodium sulfate and evaporated to dryness. The oily residue was rubbed with some drops of methanol and stood at -8°C 24 hours to give the crystals of 3-endol diester; MP: 82°-84°C, 2 g of it was dissolved in 120 ml of methanol and heated with 1.2 ml concentrated hydrochloric acid. The partly saponified product was distilled with water steam to full disappearence of smell of enantic acid. The residue was mixed with ether, washed with 2 N sulfuric acid, 2 N sodium hydroxide, finally with water to neutral dried over sodium sulfate and evaporated to dryness. The residue was stirred with pentane and cooled for crystallization. Pure enanthate was crystallized after repeated solution in pentane. 17-α-Ethinyl-19nortestosterone enanthate had MP: 68°-71°C.
  • brand name Binovum;Brevicon;Brevinor;Conceplan;Doryxas;Gesta plan;Lg 335;Menonorm;Miconor;Neocon;Nor 50;Norimin;Noristerat;Norlutate acetate;Nor-q-d;Norquentiel;Norquest fe;Novulon;Nur-isterate;Orlestrin;Ortho-novum;Ovcon-50;Ovismen;Ovysmen;Tri-norinyl.
  • Therapeutic Function Progestin
  • World Health Organization (WHO) Norethisterone enantate was introduced in 1978 for use as a longacting injectable contraceptive. Risk-benefit judgements differ significantly from country to country, having regard to differing national circumstances. Norethisterone enantate is, however, widely available and is included as a complementary drug in the WHO Model List of Essential Drugs. (Reference: (WHODI) WHO Drug Information, 2(1), , 1988)
  • Safety Profile An experimental teratogen.Questionable carcinogen with experimental tumorigenicdata. Human systemic effects by intravenous route:increased intraocular pressure. Human reproductiveeffects by intramuscular route: menstrual cycle changes ordisorders, ch
17alpha-Ethynyl-19-nortestosterone 17-heptanoate Preparation Products And Raw materials
Raw materials
Preparation Products
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3836-23-5, 17alpha-Ethynyl-19-nortestosterone 17-heptanoateRelated Search:
  • 17alpha-ethynyl-19-nortestosterone 17-heptanoate
  • NORETHISTERONE ENANTHATE
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  • NORETHISTERONE ENANTHATE, 97~102%
  • NORETHISTERONEOENANTHATE
  • [(9S,10R,13S,14S,17S)-17-ethynyl-13-methyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] heptanoate
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  • 19-Nor-17.alpha.-pregn-4-en-20-yn-3-one, 17-hydroxy-, heptanate
  • 19-Nor-17.alpha.-pregn-4-en-20-yn-3-one, 17-hydroxy-, heptanoate
  • 19-Nor-17.alpha.-pregnen-20-ynone, 17.beta.-heptanoyloxy-
  • 19-Norpregn-4-en-20-yn-3-one, 17-[(1-oxoheptyl)oxy]-, (17.alpha.)-
  • 17alpha-Ethynyl-19-n
  • 19-Norpregn-4-en-20-yn-3-one,17-[(1-oxoheptyl)oxy]-, (17a) Norethisterone Enanthate
  • norethindrone enantate
  • Norethindrone Impurity 9(Norethindrone Enanthate)
  • Norethisterone Enantate (Norethindr
  • 19-Norpregn-4-en-20-yn-3-one, 17-[(1-oxoheptyl)oxy]-, (17α)-
  • 3836-23-5
  • C27H38O3
  • Steroid and Hormone