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Nandrolone

Nandrolone Structure
Nandrolone
  • CAS No.434-22-0
  • Chemical Name:Nandrolone
  • CBNumber:CB5681525
  • Molecular Formula:C18H26O2
  • Formula Weight:274.4
  • MOL File:434-22-0.mol
Nandrolone Property
  • Melting point: :120-125 °C
  • alpha  :D22 +55° (c = 0.93 in chloroform)
  • Boiling point: :357.38°C (rough estimate)
  • Density  :1.0528 (rough estimate)
  • refractive index  :1.4800 (estimate)
  • Flash point: :2℃
  • storage temp.  :Controlled Substance, -20°C Freezer
  • pka :15.06±0.40(Predicted)
  • color  :Dimorphic crystals from CH2Cl2/Et2O
  • Water Solubility  :3.09g/L(25 ºC)
  • Merck  :6365
  • BRN  :2055849
  • InChIKey :NPAGDVCDWIYMMC-IZPLOLCNSA-N
  • CAS DataBase Reference :434-22-0(CAS DataBase Reference)
  • FDA UNII :6PG9VR430D
  • ATC code :A14AB01,S01XA11
  • NIST Chemistry Reference :Nandrolone(434-22-0)
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H351-H362-H225-H302+H312+H332-H319
  • Precautionary statements P210-P261-P302+P352+P312-P304+P340+P312-P337+P313-P403+P235-P201-P260-P263-P280
Nandrolone Price More Price(8)
  • Brand: Sigma-Aldrich
  • Product number: N-050
  • Product name : Nandrolone solution
  • Purity: 1.0mg/mL in acetonitrile, ampule of 1mL, certified reference material
  • Packaging: 050-1ml
  • Price: $129
  • Updated: 2020/08/18
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: N-050
  • Product name : Nandrolone solution
  • Purity: 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging: 1 mL
  • Price: $133
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: BP257
  • Product name : Nandrolone
  • Purity: British Pharmacopoeia (BP) Reference Standard
  • Packaging: 
  • Price: $190
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 1454008
  • Product name : Nandrolone
  • Purity: United States Pharmacopeia (USP) Reference Standard
  • Packaging: 50mg
  • Price: $1310
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 21173
  • Product name : Nandrolone
  • Purity: ≥98%
  • Packaging: 1mg
  • Price: $30
  • Updated: 2021/03/22
  • Buy: Buy

Nandrolone Chemical Properties,Usage,Production

  • Chemical Properties Crystalline Solid
  • Originator Durabolin,Organon,US,1959
  • Uses An anabolic steroid. Controlled substance (anabolic steroid)
  • Definition ChEBI: A 3-oxo Delta4-steroid that is estr-4-en-3-one substituted by a beta-hydroxy group at position 17.
  • Manufacturing Process An ice-cold solution of 1.5 grams of 19-nortestosterone and 1.5 ml of dry pyridine in 10 ml of dry benzene is prepared and a solution of 1.5 ml of β- phenylpropionyl chloride in 5 ml of dry benzene is added dropwise over a period of about 2 minutes with stirring. The resulting mixture is allowed to stand overnight under an atmosphere of nitrogen and then washed successively with cold 5% aqueous hydrochloric acid solution, cold 2.5% aqueous sodium hydroxide solution, and water. After drying over anhydrous sodium sulfate, the solvent is evaporated to give an almost colorless oil. Recrystallization from methanol gives white crystals of 19-nortestosterone 17- β-phenylpropionate, MP 91° to 92.5°C.
  • Therapeutic Function Anabolic
  • Mechanism of action Nandrolone facilitates formation of body muscle mass and strengthens the process of osseous tissue development. The main indications for using nandrolone, as well as other anabolic steroids, are abnormal protein anabolism, asthenia, diseases accompanied by protein loss, adrenal insufficiency, steroid diabetes, and prolonged condition of sluggishness.
  • Safety Profile Experimental reproductiveeffects. When heated to decomposition it emits acridsmoke and irritating fumes.
  • Chemical Synthesis Nandrolone, 17β-hydroxyester-4-en-3-one (29.1.7), is made from estradiol (28.1.17). The phenol hydroxyl group undergoes methylation by dimethylsulfate in the presence of sodium hydroxide, forming the corresponding methyl ether (29.3.1), and then the aromatic ring is reduced by lithium in liquid ammonia, which forms an enol ether (29.3.2). Hydrolyzing this compound with a mixture of hydrochloric and acetic acids leads to the formation of a keto group, and simultaneous isomerization of the double bond from C5–C10 to position C4–C5 gives the desired nandrolone (29.3.3) [16–19]. Upon necessity of using it in the form of acid esters, the product is acylated by corresponding acid derivatives.

Nandrolone Preparation Products And Raw materials
Raw materials
Preparation Products
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434-22-0, NandroloneRelated Search:
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