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GRUBBS CATALYST 2ND GENERATION

Description Reference
GRUBBS CATALYST 2ND GENERATION Structure
GRUBBS CATALYST 2ND GENERATION
  • CAS No.246047-72-3
  • Chemical Name:GRUBBS CATALYST 2ND GENERATION
  • CBNumber:CB4322469
  • Molecular Formula:C46H65Cl2N2PRu
  • Formula Weight:848.97
  • MOL File:246047-72-3.mol
GRUBBS CATALYST 2ND GENERATION Property
Safety
  • Hazard Codes  :F
  • Risk Statements  :36/37/38-11
  • Safety Statements  :26-36/37/39
  • RIDADR  :1325
  • WGK Germany  :3
  • F  :10-23
  • HazardClass  :4.1
  • PackingGroup  :
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H228
  • Precautionary statements P210
GRUBBS CATALYST 2ND GENERATION Price More Price(4)
  • Brand: Sigma-Aldrich
  • Product number: 569747
  • Product name : Grubbs Catalyst, 2nd Generation
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  • Price: $583
  • Updated: 2019/12/02
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  • Brand: Sigma-Aldrich
  • Product number: 569747
  • Product name : Grubbs Catalyst, 2nd Generation
  • Purity: 
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  • Price: $1710
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  • Brand: Sigma-Aldrich
  • Product number: 569747
  • Product name : Grubbs Catalyst, 2nd Generation
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  • Updated: 2019/12/02
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  • Brand: Sigma-Aldrich
  • Product number: 569747
  • Product name : Grubbs Catalyst, 2nd Generation
  • Purity: 
  • Packaging: 500mg
  • Price: $206
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GRUBBS CATALYST 2ND GENERATION Chemical Properties,Usage,Production

  • Description Grubbs catalysts are a series of transition metal carbene complexes used as catalyst for olefin metathesis.1 The Grubbs catalysts are based on a ruthenium atom surrounded by five ligands: two neutral electron-donating entities (e.g., trialkylphosphines, N-heterocyclic carbenes), two monoanionic groups (e.g., halides), and one alkylidene moiety (e.g., unsubstituted and substituted methylidenes). L2X2Ru=CHR complexes (where L is a phosphine ligand) were discovered first and are referred to as the first-generation Grubbs catalyst. (L)(L’)X2Ru=CHR complexes (where L is a phosphine ligand and L’ a saturated N-heterocyclic carbene or NHC ligand) are referred to as the second-generation Grubbs catalysts.
    The first-generation Grubbs catalysts show attractive functional-group tolerance and handling properties and have been widely used as highly efficient promoters for ring opening metathesis polymerizations, ring-closing metathesis reactions to make disubstituted olefins, ethenolysis (i.e., cleavage of the carbon–carbon double bond), cross-metathesis of terminal olefins, and the preparation of 1,3-dienes via enyne metathesis. These catalysts and analogues are still widely used in important processes, including the ethenolysis of feedstocks derived from bio-renewable seed oils and the manufacture of macrocyclic hepatitis C therapeutics. Nevertheless, the first-generation Grubbs catalysts show limitations with electron-poor and electron-rich double bonds as well as with sterically hindered systems. The second-generation Grubbs catalysts with excellent metathesis activity while retaining the handling characteristics and broad functional-group tolerance of the earlier Grubbs catalysts are thereby developed. At the same time, the second-generation catalysts are stable against moisture and air.
  • Reference M. L. Crawley, B. M. Trost, Applications of Transition Metal Catalysis in Drug Discovery and Development, 2012, ISBN 978-0-470-63132-4
  • Chemical Properties pink-brown to red-purple crystals or powder
  • Uses suzuki reaction
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246047-72-3, GRUBBS CATALYST 2ND GENERATIONRelated Search:
  • Grubb's second generation catalyst,97%
  • Grubbs Catalyst 2nd Generation,97+%
  • Benzylidene[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene] dichloro(tricyclohexyl-phosphine) ruthenium
  • (1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium ,97%
  • (1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium ,95%
  • Grubbs Catalyst, 2nd Generation,(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, 1,3-Bis-(2,4,6-trimethylphenyl)-2-(imidazolidinylidene
  • 1,3-Bis-(2,4,6-trimethylphenyl)-2-(imidazolidinylidene)(dichlorophenylmethylene)(tricyclohexylphosphine)ruthenium, Benzylidene[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(tricyclohexylphosphine)ruthenium
  • GRUBBS II
  • Grubbs2ndgenerationcatalyst
  • (1,3-DiMesityliMidazolin-2-ylidene)(tricyclohexylphosphine)rutheniuM dichloride
  • [1,3-bis(2,4,6-triMethylphenyl)iMidazolidin-2-ylidene](phenylMethylidene)(tricyclohexyl-$l^{5}-phosphanyl)rutheniuMbis(yliuM) dichloride
  • Grubbs Catalyst 2nd Generation Grubbs
  • 2nd generation Grubbs catalyst
  • Grubb's II Catalyst
  • Grubbs (2nd generation)
  • Grubbs Catalyst, 2<SUP>nd</SUP> Generation
  • Grubb's second generation catalyst
  • GRUBBS CATALYST 2ND GENERATION
  • Kuffer Cell
  • (1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(PHENYLMETHYLENE)(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM
  • RUTHENIUM,[1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE]DICHLORO (PHENYLMETHYLENE) (TRICYCLOHEXYLPHOSPHINE)
  • Tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene][benzylidene]rut
  • Tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene][benzylidine]Ruthenium(IV)dichloride
  • BENZYLIDENE[1,3-DIMESITYL-2-IMIDAZOL.]-C L2-(TRI-CHEX-P)-RU
  • Tricyclohexylphosphine1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-yli
  • GRUBBS CATALYST,2 ND GEN
  • Benzylidene(dichloro)(1,3-diMesityl-2-iMidazolidinylidene)rutheniuM - tricyclohexylphosphine (1:1)
  • Grubbs Catalyst, 2nd
  • RutheniuM,[1,3-bis(2,4,6-triMethylphenyl)-2-iMidazolidinylidene]dichloro(phenylMethylene)(tricyclohexylphosphine)-,(SP-5-41)-
  • Grubbs Gen 2nd
  • Catalyst, 2nd Generation
  • Grubbs catalyst II
  • Grubbs Catalyst, 2nd Generation≥ 98% (NMR)
  • (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium Benzylidene[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(tricyclohexylphosphine)ruthenium [1
  • (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium
  • (SP-5-41)-[1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium
  • benzylidene-[1,3-bis(2,4,6-trimethylphenyl)imidazolidin-2-ylidene]-dichlororuthenium,tricyclohexylphosphane
  • 1,3-Bis-(2,4,6-trimethylphenyl)-2-(imidazolidinylidene)(dichlorophenylmethylene)(tricyclohexylphosphine)ruthenium, Benzylidene[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(tricyclohexylphosphine)ruthenium, (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium
  • 246047-72-3
  • C46H65Cl2N2PRu
  • Catalysis and Inorganic Chemistry
  • Metathesis Catalysts
  • Ru