Bis(tricyclohexylphosphine)nickel(II) chloride, 99%

Reaction

1. An approach to five-membered lactams from aliphatic amides and terminal acetylenes by nickel catalysis.
2. Synthesis of biaryls through nickel-catalyzed Suzuki-Miyaura coupling of amides by carbon-nitrogen bond cleavage.
3. Ni-catalyzed borylation of aryl fluorides via C-F cleavage.
4. Nickeland palladium–catalyzed coupling of aryl fluorosulfonates with aryl boronic acids enabled by sulfuryl fluoride.
5. Nickel-catalyzed one-pot synthesis of biaryls from phenols and arylboronic acids via C-O activation using TCT reagents.

Uses

• Dehydrobrominative polycondensation
• Arylation reactions
• Cross-coupling
• Suzuki-miyaura cross-coupling reactions
• Kumada coupling of diaryl sulfates with Grignard reagents
• Olefin dimerization