[1,3-Bis(diphenylphosphino)propane]nickel(II) chloride

Reaction

1. Nickel catalyst used in the N-heterocycle-directed cross-coupling of fluorinated arenes with organozinc reagents.
2. Nickel catalyst used in the (E)-selective semihydrogenation of internal alkynes.
3. Nickel catalyst used in the borylation of halides and pseudohalides.

Chemical Properties

red to red-brown powder or crystals

Uses

suzuki reaction.
Dichloro[bis(1,3-diphenylphosphino)propane]nickel(II) is used as an effective catalyst for Kumada coupling and Suzuki reactions. It also catalyzes other reactions to convert enol ethers, dithioacetals and vinyl sulfides to olefins. Further, it is used as a catalyst for preparation of block-copolythiophenes and solid state metathesis polycondensation.

Application

Catalyst for:
Synthesis of block-copolythiophenes
Suzuki-Miyaura cross-coupling reaction of aryl halides with arylboronic acids
Solid state metathesis polycondensation
Polymerization of poly(3-alkoxythiophene)s
Diastereoselective Nozaki-Hiyama-Kishi coupling reactions of C1-C19 fragment of macrolide antibiotic aplyronine A
Transfer condensation polymerization of conjugated polymers
[1,3-Bis(diphenylphosphino)propane]dichloronickel(II) can be used as a precursor to synthesize metal-fullerene coordination complexes by reduction method.