2-Phenylindole Struktur

2-Phenylindol

Bezeichnung:2-Phenylindol

CAS-Nr948-65-2

Englisch Name:2-Phenylindole

CBNumberCB9725557

SummenformelC14H11N

Molgewicht193.24

MOL-Datei948-65-2.mol

Synonyma

2-Phenylindol

2-Phenylindol physikalisch-chemischer Eigenschaften

Schmelzpunkt	188-190 °C (lit.)
Siedepunkt	250 °C/10 mmHg (lit.)
Dichte	1.1061 (rough estimate)
Brechungsindex	1.5850 (estimate)
Flammpunkt	250°C/10mm
storage temp.	Sealed in dry,Room Temperature
Löslichkeit	almost transparency in Methanol
pka	16.80±0.30(Predicted)
Aggregatzustand	Powder
Farbe	Off-white to beige or slightly green
CAS Datenbank	948-65-2(CAS DataBase Reference)
NIST chemische Informationen	1H-Indole, 2-phenyl-(948-65-2)
EPA chemische Informationen	1H-Indole, 2-phenyl- (948-65-2)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	37/38-41
S-Sätze:	26-39
WGK Germany	3
RTECS-Nr.	NM1272500
TSCA	Yes
HS Code	29309090

Gefahreninformationscode (GHS)

2-Phenylindole Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R37/38:Reizt die Atmungsorgane und die Haut.
R41:Gefahr ernster Augenschäden.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S39:Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
off-white to beige or slightly green powder
Verwenden
Reactant for preparation of:
- Oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition
- Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
- Organic light emitting diodes (OLEDs)
- Anti inflammatory agents
- Potential cyclooxygenase-1 (COX-1)/cyclooxygenase-2 (COX-2) inhibitors
- Agents for cancer and malaria therapy
- Antifungal and antibacterial agents
- Fluorescent probes
Reactant in:
- Difluorohydroxylation reactions?
- Mannich-type reactions?
Verwenden
Reactant for preparation of: • ;Oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition1• ;Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators2• ;Organic light emitting diodes (OLEDs)3• ;Anti inflammatory agents4• ;Potential cyclooxygenase-1 (COX-1)/cyclooxygenase-2 (COX-2) inhibitors5• ;Agents for cancer and malaria therapy6• ;Antifungal and antibacterial agents7• ;Fluorescent probes8Reactant in:• ;Difluorohydroxylation reactions†• ;Mannich-type reactions†
Verwenden
Phenylindole is a stabilizer in PVC-plastic products (α-phenylindole).
synthetische
2-phenylindole is prepared by condensing phenylhydrazine and acetophenone, and then closing the ring in the presence of zinc chloride. or it can be prepared by heating bromoacetophenone with excess aniline, or heating N-(2-methylphenyl)benzamide and sodium ethoxide at 360-380℃ in isolation from air.
Definition
ChEBI: 2-phenyl-1H-indole is a phenylindole.
Synthesis Reference(s)
Tetrahedron Letters, 33, p. 1459, 1992 DOI: 10.1016/S0040-4039(00)91646-0
Journal of Heterocyclic Chemistry, 29, p. 1085, 1992 DOI: 10.1002/jhet.5570290509

2-Phenylindole Upstream-Materialien And Downstream Produkte

2-Phenylindol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

948-65-2, 2-Phenylindole Verwandte Suche:

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