2,4'-Dichlor-α(pyrimidin-5-yl)benzhydrylalkohol

Bezeichnung:2,4'-Dichlor-α(pyrimidin-5-yl)benzhydrylalkohol

CAS-Nr60168-88-9

Englisch Name:Fenarimol

CBNumberCB9431616

SummenformelC17H12Cl2N2O

Molgewicht331.2

MOL-Datei60168-88-9.mol

Synonyma

2,4'-Dichlor-α(pyrimidin-5-yl)benzhydrylalkohol

2,4'-Dichlor-α(pyrimidin-5-yl)benzhydrylalkohol physikalisch-chemischer Eigenschaften

Schmelzpunkt	117-119°C
Siedepunkt	0°C
Dichte	1.3886 (rough estimate)
Dampfdruck	6.5 x 10^-5 Pa at 25 °C
Brechungsindex	1.5490 (estimate)
Flammpunkt	0°C
storage temp.	0-6°C
Löslichkeit	Chloroform (Slightly), Methanol (Slightly)
pka	2.58
Wasserlöslichkeit	14.6 mg l^-1 (pH 3), 13.7 mg l^-1 (pH 7), 13.8 mg l^-1 (pH 10) at 25 °C
Farbe	Off-White to Light Yellow
Merck	13,3986
BRN	5972869
CAS Datenbank	60168-88-9(CAS DataBase Reference)
NIST chemische Informationen	5-Pyrimidinemethanol, «alpha»-(2-chlorophenyl)-«alpha»-(4-chlorophenyl)-(60168-88-9)
EPA chemische Informationen	Fenarimol (60168-88-9)

Sicherheit

Kennzeichnung gefährlicher	Xn;N,N,Xn
R-Sätze:	51/53-62-63-64
S-Sätze:	36/37-61
RIDADR	UN 3017/3077
WGK Germany	2
RTECS-Nr.	UV9279400
Toxizität	LD50 in mice, rats (mg/kg): 4500, 2500 orally (Beraud)

Gefahreninformationscode (GHS)

Fenarimol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R51/53:Giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.
R62:Kann möglicherweise die Fortpflanzungsfähigkeit beeinträchtigen.
R63:Kann das Kind im Mutterleib möglicherweise schädigen.
R64:Kann Säuglinge über die Muttermilch schädigen.
S-Sätze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
Verwenden
Fenarimol is a pyrimidine based fungicide which acts against rusts, blackspot and mildew fungi and it works by inhibiting the fungus’s biosynthesis of important steroid molecules.
Verwenden
Fenarimol is a broad spectrum pyrimidine carbinol fungicide with protective, curative and eradicative activities against powdery mildew (Erysiphe spp., Pudusphaera leucutricha, Uncinula necatur, Sphaerutheca spp., Leveillula spp.) and scab (Venturia spp.) in many crops. It also controls powdery mildew (Sphaerutheca pannusa) in ornamentals and Fusarium patch (Micruduccium niuale), Take-all patch (Laefisaria fuciformis), Dollar spot (Sderutina humeucavpa) and red thread (Gaeumannumyces graminis) in turf and amenity grasses.
Verwenden
Plant fungicide.
Definition
ChEBI: (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol is a member of the class of pyrimidines that is pyrimidin-5-ylmethanol in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 2-chlorophenyl group while the other is replaced by a 4-chlorophenyl group. It is a tertiary alcohol, a member of monochlorobenzenes and a member of pyrimidines.
Allgemeine Beschreibung
Pure white crystalline solid. Used as a fungicide. Irritates skin and mucous membranes.
Reaktivität anzeigen
Fenarimol produces toxic gases when heated to decomposition.
Sicherheitsprofil
Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Cland NOx.
Stoffwechselwegen
The primary dissipation mechanism of fenarimol in the environment involves photolysis on plants/soil surfaces and water. More than 80 photoproducts have been observed, resulting from the reduction of the pyrimidine ring, hydrolysis, ring migration and cleavage of the phenyl and pyrimidine ring moieties. Under laboratory conditions in the dark, fenarimol is relatively persistent in soil, but a more rapid dissipation was observed under field conditions with DT₅₀ values of 18-140 days, attributed to photolysis of fenarimol on the soil surface. Fenarimol degrades in/on plant foliage/fruit surfaces mainly by photochemical processes. In animals, fenarimol is metabolised extensively to yield hydroxylated, cleavage and dechlorination products. The primary photolytic and metabolic pathways of fenarimol are presented in Schemes 1 and 2.
Degradation
Fenarimol(1) is stable in sterile buffered water in the dark at pH 3,6 and 9 at 25 °C, 37 °C and 52 °C for 28 days (Decker and Sullivan, 1975) but is readily degraded via photolysis. The photolytic DT₅₀ in distilled water under natural sunlight and clear sky conditions at 40°N in mid-summer was approximately 12 hours (Day, 1975). The primary aqueous photolysis reaction involved the migration of the pyrimidine ring to one of the chlorophenyl rings, followed by the oxidation of the carbinol moiety to the corresponding ketone to yield 4-chloro-2-(5-pyrimidyl)-2'-chlorobenzophenone (2).
Fenarimol was extensively photodegraded on solid surfaces. More than 80 photodegradation products were formed when fenarimol was exposed to sunlight on a stainless steel surface for up to 200 hours (Althaus and Bewley, 1978a). All photoproducts were formed at very low levels (less than 3% each) and 14 were identified. An abbreviated photogradation pathway of fenarimol is presented in Scheme 1. These products were generated from the following reactions: the migration of the pyrimidine ring to one of the chlorophenyl rings, followed by the oxidation of the carbinol moiety to yield compound 2; cleavage of either one of the chlorophenyl (to yield 3,4) or pyrimidine rings (5,6); aryl hydroxylation of one of the chlorophenyl rings (7); carbinol dehydroxylation reaction to yield 8 and a bridged fluorene product (9) from the dechlorination reaction. Various cleavage products (carboxylic acids) derived from the chlorophenyl (10-13) and the pyrimidine moieties (14) were also observed.

Fenarimol Upstream-Materialien And Downstream Produkte

2,4'-Dichlor-α(pyrimidin-5-yl)benzhydrylalkohol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

60168-88-9, Fenarimol Verwandte Suche:

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