4-Amino-1-Boc-piperidine

Bezeichnung:4-Amino-1-Boc-piperidine

CAS-Nr87120-72-7

Englisch Name:4-Amino-1-Boc-piperidine

CBNumberCB8758747

SummenformelC10H20N2O2

Molgewicht200.28

MOL-Datei87120-72-7.mol

4-Amino-1-Boc-piperidine physikalisch-chemischer Eigenschaften

Schmelzpunkt	50°C
Siedepunkt	80/0.037mm
Dichte	1.041±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	10.10±0.20(Predicted)
Aggregatzustand	Crystalline Powder, Crystals and/or Chunks
Farbe	White to pale yellow to beige
Wasserlöslichkeit	Insoluble in water.
Sensitive	Air Sensitive
InChI	InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-8(11)5-7-12/h8H,4-7,11H2,1-3H3
InChIKey	LZRDHSFPLUWYAX-UHFFFAOYSA-N
SMILES	N1(C(OC(C)(C)C)=O)CCC(N)CC1
CAS Datenbank	87120-72-7(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	22-37/38-41-36/37/38-20/21/22-20/21/2236/37/38
S-Sätze:	26-36/37/39-22-222636/37/39
RIDADR	3259
WGK Germany	2
F	10-34
Hazard Note	Irritant
TSCA	N
HazardClass	8
PackingGroup	Ⅲ
HS Code	29339900

Gefahreninformationscode (GHS)

4-Amino-1-Boc-piperidine Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R37/38:Reizt die Atmungsorgane und die Haut.
R41:Gefahr ernster Augenschäden.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S22:Staub nicht einatmen.
Chemische Eigenschaften
white to light yellow crystal powder
Verwenden
4-Amino-1-Boc-piperidine is a potent inhibitor of the CCR5 receptor. It is an x-ray crystal structure with a hydroxide solution that inhibits the growth of cancer cells. The inhibitor binding site for 4-Amino-1-Boc-piperidine was determined to be the CCR5 receptor, which is located on the surface of hematopoietic cells. The compound has been shown to inhibit human T lymphocyte proliferation in vitro and inhibit HIV replication in infected patients. 4-Amino-1-Boc-piperidine is able to inhibit the growth of cancer cells by blocking the production of cytokines, such as interleukin 2, that are needed for cell division and growth.
Verwenden
4-Amino-1-Boc-piperidine is a chemical reagent used in the preparation of pharmaceutical compounds. Used in the synthesis of bromodomain inhibitors as well as HepG2 cell cycle inhibitors used in anti-tumor therapy. Also employed in a microwave-assisted solid-phase synthesis of N-substituted piperidines via direct annulation of primary amines with resin-bound dimesylates.
Application
4-Amino-1-Boc-piperidine is a pharmaceutical intermediate is applied in the treatment of anti-tumor and other drugs. It is an important fine chemical intermediate and has a wide range of uses in the pharmaceutical industry.

4-Amino-1-Boc-piperidine Upstream-Materialien And Downstream Produkte

87120-72-7, 4-Amino-1-Boc-piperidine Verwandte Suche:

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