(E)-Chalkon

Bezeichnung:(E)-Chalkon

CAS-Nr614-47-1

Englisch Name:trans-Chalcone

CBNumberCB7746253

SummenformelC15H12O

Molgewicht208.26

MOL-Datei614-47-1.mol

Synonyma

(E)-Chalkon

(E)-Chalkon physikalisch-chemischer Eigenschaften

Schmelzpunkt	55-59 °C
Siedepunkt	208 °C25 mm Hg(lit.)
Dichte	1.0712
Brechungsindex	1.5361 (estimate)
Flammpunkt	>230 °F
storage temp.	Sealed in dry,Room Temperature
Löslichkeit	Chloroform (Slightly)
Aggregatzustand	Solid
Farbe	Pale Yellow
Geruch (Odor)	at 100.00 %. floral balsam herbal
Geruchsart	floral
Wasserlöslichkeit	Soluble in chloroform, ether, benzene, and ethanol (slightly). Insoluble in water.
Merck	14,2037
BRN	509985
LogP	4.013 (est)
CAS Datenbank	614-47-1(CAS DataBase Reference)
NIST chemische Informationen	Benzalacetophenone(614-47-1)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	22-36/37
S-Sätze:	22-36/37/39-45
WGK Germany	3
RTECS-Nr.	UD5576750
HS Code	29143990

Gefahreninformationscode (GHS)

trans-Chalcone Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R36/37:Reizt die Augen und die Atmungsorgane.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Beschreibung
trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer.
Chemische Eigenschaften
Trans-Chalcone is a yellowish crystals. M.P. 58℃. (trans-isomer). M .P. 46℃. (cis-isomer).Sp.Gr. 1.07 (liquid).Insoluble in water, soluble in alcohol (poorly) and oils.
Verwenden
trans-Chalcone is a positive allosteric modulator of α7 nicotinic acetylcholine receptors and exhibits antioxidant activity.
Definition
ChEBI: Chalcone is a member of the class of chalcones that is acetophenone in which one of the methyl hydrogens has been replaced by a benzylidene group. It has a role as a plant metabolite. It is a member of styrenes and a member of chalcones.
Application
trans-Chalcone was used in the synthesis of cis and trans diphenyl cyclopropane. It was also used in screening of surface adsorbed species of isobutybenzene and 4-isobutylacetophenone on bulk fosfotungstic Wells-Dawson acid (H6P2W18O62.xH2O).
synthetische
trans-Chalcones have been obtained in good yields and selectivities following an environmentally friendly methodology by using montmorillonite KSF as a reusable heterogeneous catalyst.
Clay-catalysed solventless synthesis of trans-chalcones
Synthesis Reference(s)
Journal of the American Chemical Society, 104, p. 4724, 1982 DOI: 10.1021/ja00381a058
Allgemeine Beschreibung
trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer.
Biologische Aktivität
trans-Chalcone exhibits antifungal activity against Trichophyton rubrum. It is inhibitor of fatty acid synthase and α-amylase. It induces programmed cell death due to reduced mitochondrial transmembrane potential in Arabidopsis thaliana roots.
Biochem/physiol Actions
trans-Chalcone exhibits antifungal activity against Trichophyton rubrum. It is inhibitor of fatty acid synthase and α-amylase. It induces programmed cell death due to reduced mitochondrial transmembrane potential in Arabidopsis thaliana roots.
Synthese
Trans-Chalcone is synthesized by condensation of Benzaldehyde with Acetophenone.

trans-Chalcone Upstream-Materialien And Downstream Produkte

(E)-Chalkon Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

614-47-1, trans-Chalcone Verwandte Suche:

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