Etofenamat

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Achtung

• Gefahrenhinweise

  H301：Giftig bei Verschlucken.

  H410：Sehr giftig für Wasserorganismen mit langfristiger Wirkung.

Etofenamate Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  Light Yellow Oil

• Originator

  Rheumon,Troponwerke,W. Germany,1977

• Verwenden

  As a histamine H1 -receptor antagonist, Etofenamate can be used as anti-inflammatory;cyclooxygenase inhibitor and medication used to alleviate joint and muscle pain.

• Definition

  ChEBI: 2-[3-(trifluoromethyl)anilino]benzoic acid 2-(2-hydroxyethoxy)ethyl ester is a benzoate ester.

• Manufacturing Process

  16.0 g (0.05 mol) of the potassium salt of N-(3-trifluoromethylphenyl)- anthranilic acid are dissolved in 60 ml of dimethylformamide and heated to 110°C, and 6.2 g (0.05 mol) of 2-(2-chloroethoxy)-ethanol are slowly added. The reaction mixture is then heated to boiling for 2 hours. The precipitated potassium chloride is filtered off and the solvent is removed by evaporation. The residue is separated over a column with 400 g of silica gel (particle size 0.05 to 0.2 mm), using a 1:1 mixture of cyclohexane and glacial acetic acid as eluting agent. 16.0 g of the 2-(2-hydroxyethoxy)-ethyl ester of N-(3- trifluoromethylphenyl)-anthranilic acid are obtained in the form of a pale yellow oil which does not crystallize and cannot be distilled.

• Therapeutic Function

  Antiinflammatory

Etofenamate Upstream-Materialien And Downstream Produkte

Etofenamat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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