(R)-16α,17-[(1-Phenylethyliden)dioxy]pregn-4-en-3,20-dion

Algestone acetophenide Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Neolutin Depo, Medici ,Italy ,1982

• Verwenden

  Progestin.

• Verwenden

  Algestone Acetophenide is a progestational steroid that has been shown to increase the proteins in milk and serum in goats and decrease the weight gain of kids. Algestone Acetophenide is used as an injectable steroid contraceptive in Chile and Mexico.

• Definition

  ChEBI: Algestone acetophenide is a 16alpha,17alpha-dihydroxyprogesterone acetophenide. It has a role as an anti-inflammatory drug and a synthetic oral contraceptive.

• Manufacturing Process

  To a suspension of 500 mg of 16α,17α-dihydroxyprogesterone in 25 ml of freshly redistilled acetophenone is added 0.125 ml of 72% perchloric acid and the mixture is agitated at room temperature for one hour. The clear solution is washed with dilute sodium bicarbonate to remove excess acid and the acetophenone layer, after addition of chloroform is separated from the aqueous phase. The organic layer is dried over sodium sulfate and after removal of the chloroform and acetophenone in high vacuum the residue is crystallized from 95% alcohol. The pure acetophenone derivative has a melting point of about 142°C to 144°C.

• Trademarks

  Deladroxone (Bristol-Myers Squibb); Droxone (Bristol-Myers Squibb).

• Therapeutic Function

  Progestin, Contraceptive

Algestone acetophenide Upstream-Materialien And Downstream Produkte

(R)-16α,17-[(1-Phenylethyliden)dioxy]pregn-4-en-3,20-dion Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(152)Suppliers

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