strogene, Konjugate
Bezeichnung:strogene, Konjugate
CAS-Nr12126-59-9
Englisch Name:Premarin
CBNumberCB0483920
SummenformelC18H19NaO5S
Molgewicht370.4
MOL-Datei12126-59-9.mol
Synonyma
strogene, Konjugate
strogene, Konjugate physikalisch-chemischer Eigenschaften
CAS Datenbank | 12126-59-9(CAS DataBase Reference) |
Gefahreninformationscode (GHS)
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Bildanzeige (GHS)
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Alarmwort
Achtung
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Gefahrenhinweise
H315:Verursacht Hautreizungen.
H319:Verursacht schwere Augenreizung.
H335:Kann die Atemwege reizen.
H350:Kann Krebs verursachen.
H360:Kann die Fruchtbarkeit beeinträchtigen oder das Kind im Mutterleib schädigen.
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Sicherheit
P264:Nach Gebrauch gründlich waschen.
P264:Nach Gebrauch gründlich waschen.
P280:Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P302+P352:BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.
P305+P351+P338:BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.
P321:Besondere Behandlung
P332+P313:Bei Hautreizung: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
P362:Kontaminierte Kleidung ausziehen und vor erneutem Tragen waschen.
Premarin Chemische Eigenschaften,Einsatz,Produktion Methoden
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Beschreibung
Conjugated estrogens generally occur as butter-colored powders that are soluble in water. The sodiumequilin sulfate component is unstable to light and air.Piperazine estrone sulfate occurs as a white to yellowishwhite crystalline powder that is slightly soluble in water.Piperazine estrone sulfate melts at 245℃ with decomposition. Conjugated estrogens are naturally occurring substances excreted in the urine of pregnant mares; piperazineestrone sulfate is not known to occur naturally. -
Chemische Eigenschaften
Conjugated estrogens generally occur as butter-colored powders -
Chemische Eigenschaften
Almost white or brownish, amorphous powder. -
Verwenden
Conjugated Estrogen is a mixture of estrogen derivatives-mostly estrone and equilin sulfate. -
Definition
ChEBI: Equilin sodium sulfate is a steroid sulfate. It is functionally related to an equilin. -
Sicherheitsprofil
Suspected human carcinogen producing tumors of the vascular system and liver. Human reproductive effects: changes in female fertility. When heated to decomposition it emits toxic fumes of NazO. See also indvidual components. -
mögliche Exposition
Conjugated estrogens are naturally occurring substances excreted in the urine of pregnant mares; piperazine estrone sulfate is not known to occur naturally. Conjugated estrogens are used to treat symptoms of the climacteric, vulvae dystrophies; female hypogonadism; and dysfunctional uterine bleeding. They also are used for treatment following: ovariectomy, for chemotherapy of mammary cancer and prostate carcinogema; and for prevention of postpartum breast engorgement. In addition, conjugated estrogens have been found in cosmetic preparations -
Erste Hilfe
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit. -
Lager
Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. A regulated, marked area should be establishedwhere this chemical is handled, used, or stored in compliance with OSHA Standard 1910.1045. -
Versand/Shipping
UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required. UN3249 Medicine, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials. PGIII. -
Inkompatibilitäten
Estrogens are Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, acid chlorides, and acid anhydrides. -
Waste disposal
It is inappropriate and possibly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quantities of expired or waste pharmaceuticals may be mixed with wet cat litter or coffee grounds, double-bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged, and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator
strogene, Konjugate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
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