5-Amino-o-kresol

Bezeichnung:5-Amino-o-kresol

CAS-Nr2835-95-2

Englisch Name:5-Amino-o-cresol

CBNumberCB5116645

SummenformelC7H9NO

Molgewicht123.15

MOL-Datei2835-95-2.mol

Synonyma

5-Amino-o-kresol

5-Amino-o-kresol physikalisch-chemischer Eigenschaften

Schmelzpunkt	160-162 °C(lit.)
Siedepunkt	229.26°C (rough estimate)
Dichte	1.0877 (rough estimate)
Dampfdruck	0.002Pa at 25℃
Brechungsindex	1.5380 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Löslichkeit	DMSO (Slightly), Methanol (Slightly)
pka	10.36±0.10(Predicted)
Aggregatzustand	Powder
Farbe	Pale brown
Wasserlöslichkeit	4.11g/L at 20℃
BRN	2802317
Kosmetik-Inhaltsstoffe Funktionen	HAIR DYEING
Erinnerung an die inhaltsstoffe	5-Amino-o-cresol (2835-95-2)
InChI	1S/C7H9NO/c1-5-2-3-6(8)4-7(5)9/h2-4,9H,8H2,1H3
InChIKey	DBFYESDCPWWCHN-UHFFFAOYSA-N
SMILES	Cc1ccc(N)cc1O
LogP	0.53 at 20℃
CAS Datenbank	2835-95-2(CAS DataBase Reference)
EPA chemische Informationen	5-Amino-2-methylphenol (2835-95-2)

Sicherheit

Kennzeichnung gefährlicher	Xi,Xn
R-Sätze:	36/37/38-20/21/22
S-Sätze:	26-36-37/39
WGK Germany	1
RTECS-Nr.	SJ6090000
TSCA	TSCA listed
HS Code	29222990
Speicherklasse	11 - Combustible Solids
Hazard Classifications	Eye Irrit. 2 Skin Irrit. 2 STOT SE 3
Giftige Stoffe Daten	2835-95-2(Hazardous Substances Data)
Toxizität	bird - domestic,LD50,oral,562mg/kg (562mg/kg),Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.

Gefahreninformationscode (GHS)

5-Amino-o-cresol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
Beige crystals
Verwenden
The spectrophotometric course of the reaction of 5-amino-2-methylphenol with p-benzoquinone di-imine was studied.
Allgemeine Beschreibung
Brown powder.
Air & Water Reaktionen
Insoluble in water.
Reaktivität anzeigen
5-Amino-o-cresol reacts with strong oxidizing agents.
Brandgefahr
Flash point data are not available for 5-Amino-o-cresol, but 5-Amino-o-cresol is probably combustible.
Flammability and Explosibility
Not classified
Synthese

95-74-9

2835-95-2

General procedure for the synthesis of 2-methyl-5-aminophenol from 3-chloro-4-methylaniline: 1700 kg of 50% sodium hydroxide solution was added to a 4800 L autoclave, followed by 1850 kg of ethanol solution containing 1000 kg of 3-chloro-4-methylaniline. Then 50kg of cuprous chloride and 15kg of copper powder were added as catalyst. The reaction vessel was sealed and replaced with nitrogen five times to ensure an oxygen-free environment. The reaction mixture was heated to 175°C and maintained at this temperature for 4 hours, during which time it was sampled and analyzed to monitor the progress of the reaction. Upon completion of the reaction, the mixture was cooled to room temperature. Ethanol was recovered under reduced pressure and then the reaction mixture was filtered and transferred to an 8000 L tank. The pH was adjusted to weak acidity by adding 1450 kg of industrial hydrochloric acid to the filtrate. Extraction was carried out with 2000L of ethyl acetate for three times. The organic phases were combined and the ethyl acetate was recovered by distillation under reduced pressure to obtain the crude product. To the crude product, 1000kg of ethanol was added, heated to 60°C to dissolve, and then 50kg of activated carbon was added to decolorize. After stirring for 1 hour, the activated carbon was removed by hot filtration and the filtrate was cooled to 5°C for crystallization. Finally, 707kg of 2-methyl-5-aminophenol was obtained with a yield of 85.36% and a purity of 99.8%.
Einzelnachweise
[1] Patent: CN107963974, 2018, A. Location in patent: Paragraph 0030-0032; 0036; 0037

5-Amino-o-cresol Upstream-Materialien And Downstream Produkte

5-Amino-o-kresol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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