Orthophosphorsure

Bezeichnung:Orthophosphorsure

CAS-Nr7664-38-2

Englisch Name:Phosphoric acid

CBNumberCB3854273

SummenformelH3O4P

Molgewicht98

MOL-Datei7664-38-2.mol

Synonyma

Orthophosphorsure

Orthophosphorsäure

Orthophosphorsure physikalisch-chemischer Eigenschaften

Schmelzpunkt	~40 °C(lit.)
Siedepunkt	158 °C(lit.)
Dichte	1.685 g/mL at 25 °C(lit.)
Dampfdichte	3.4 (vs air)
Dampfdruck	2.2 mm Hg ( 20 °C)
Brechungsindex	n20/D 1.433
FEMA	2900 \| PHOSPHORIC ACID
storage temp.	no restrictions.
Löslichkeit	H₂O: soluble
pka	2.1-7.2-12.3(at 25℃)
Aggregatzustand	Solid or Viscous Liquid
Wichte	1.7
Farbe	≤10(APHA)
PH	3.06(1 mM solution);2.26(10 mM solution);1.63(100 mM solution);
Geruch (Odor)	Odorless
Säure-Base-Indikators(pH-Indikatoren)	1.5
Wasserlöslichkeit	MISCIBLE
maximale Wellenlänge (λmax)	λ: 260 nm Amax: ≤0.05 λ: 280 nm Amax: ≤0.04
Merck	14,7344
BRN	1921286
Expositionsgrenzwerte	TLV-TWA 1 mg/m³ (ACGIH, MSHA, and OSHA); TLV-STEL 3 mg/m³ (ACGIH).
Dielectric constant	61.0
InChIKey	NBIIXXVUZAFLBC-UHFFFAOYSA-N
LogP	-2.15
CAS Datenbank	7664-38-2(CAS DataBase Reference)
NIST chemische Informationen	Phosphoric acid(7664-38-2)
EPA chemische Informationen	Phosphoric acid (7664-38-2)

Sicherheit

Kennzeichnung gefährlicher	C,Xn,T,F
R-Sätze:	34-35-22-39/23/24/25-36/38-23/24/25-11
S-Sätze:	7-16-26-36/37-45-36/37/39-1/2-24/25
RIDADR	UN 3453 8/PG 3
OEB	C
OEL	TWA: 1 mg/m3, STEL: 3 mg/m3
WGK Germany	3
RTECS-Nr.	TB6300000
F	3-10
TSCA	Yes
HS Code	2809 20 00
HazardClass	8
PackingGroup	III
Giftige Stoffe Daten	7664-38-2(Hazardous Substances Data)
Toxizität	ADI 0 to 70 mg / kg (total phosphate content in terms of phosphorus, FAO / WHO, 2001). GRAS (FDA, § 182.1073, 2000). LD501530mg / kg (rat, oral). In case of daily intake of 2 ~ 4 g, it can cause mild diarrhea. The amount of sour agent used as a cola drink is 0.02% to 0.06%.
IDLA	1,000 mg/m3

Gefahreninformationscode (GHS)

Phosphoric acid Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD
HYGROSKOPISCHE, FARBLOSE KRISTALLE.
ARBEITSPLATZGRENZWERTE
TLV: 1 mg/m?(als TWA); 3 mg/m?(als STEL); (ACGIH 2005).
MAK: 2 mg/m?(Einatembare Fraktion); Spitzenbegrenzung: überschreitungsfaktor I(2); Schwangerschaft: Gruppe C; (DFG 2005).
EG Arbeitsplatz-Richtgrenzwerte: 1 mg/m?(als TWA); 2 mg/m?(als STEL); (EG 2004).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation des Aerosols und durch Verschlucken.
INHALATIONSGEFAHREN
Beim Verdampfen bei 20°C tritt eine gesundheitsschädliche Kontamination der Luft nicht oder nur sehr langsam ein
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION:
Die Substanz verätzt die Augen, die Haut und die Atemwege. ätzend beim Verschlucken.
LECKAGE
Verschüttetes Material in abgedeckten Behältern sammeln; falls erforderlich durch Anfeuchten Staubentwicklung verhindern. Reste sorgfältig sammeln. An sicheren Ort bringen. Chemikalienschutzanzug mit umgebungsluftunabhängigem Atemschutzgerät.
R-Sätze Betriebsanweisung:
R34:Verursacht Verätzungen.
R35:Verursacht schwere Verätzungen.
R22:Gesundheitsschädlich beim Verschlucken.
R39/23/24/25:Giftig: ernste Gefahr irreversiblen Schadens durch Einatmen, Berührung mit der Haut und durch Verschlucken.
R36/38:Reizt die Augen und die Haut.
R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
R11:Leichtentzündlich.
S-Sätze Betriebsanweisung:
S7:Behälter dicht geschlossen halten.
S16:Von Zündquellen fernhalten - Nicht rauchen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S1/2:Unter Verschluss und für Kinder unzugänglich aufbewahren.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Phosphoric acid was prepared first by Robert Boyle in 1694 by dissolving phosphorus pentoxide in water. Phosphoric acid is probably the most important compound of phosphorus. It is the second largest inorganic chemical by volume, after sulfuric acid, marketed in the United States.
The single most important application of Phosphoric acid is manufacturing phosphate salts for fertilizers. Such fertilizer phosphates include sodium, calcium, ammonium, and potassium phosphates. Other applications are in metal pickling and surface treatment for removal of metal oxides from metal surfaces; electropolishing of aluminum; as a bonding agent in various refractory products such as alumina and magnesia; as a catalyst in making nylon and gasoline; as a dehydrating agent; in fireproofing wood and fabrics; in lithographic engraving; in textile dyeing; in dental cement; in coagulating rubber latex; in purifying hydrogen peroxide; and as a laboratory reagent. Dilute solutions of phosphoric acid are used as additives to carbonated beverages for a pleasing sour taste. Also, dilute acid is used in refining sugar; as a nutrient; and as a buffering agent in preparing jam, jelly, and antibiotics. The commercial phosphoric acid is 85% (w/w) in strength.
Chemische Eigenschaften
Phosphoric acid is a colorless, odorless, crystalline solid or a thick syrupy liquid. Physical state is strength and temperature dependent.
Concentrated phosphoric acid occurs as a colorless, odorless, syrupy liquid. It has a pleasing acid taste when suitably diluted.
Pure phosphoric acid, also called orthophosphoric acid, is a clear, colorless, mineral acid with moderate strength. It is normally marketed as an aqueous solution of 75–85% in which it exists as a clear, viscous liquid.

Food-grade phosphoric acid is used to acidify foods and beverages. It provides a tangy or sour taste and, being a mass-produced chemical, is available cheaply and in large quantities. Phosphoric acid, used in many soft drinks, has been linked to lower bone density in epidemiological studies. In brief, phosphoric acid is a strong acid and common industrial chemical used in the manufacture of a wide number of products, notably porcelain and metal cleaners, detergents, and fertilisers. It is also used as a food additive and is a major constituent of many soft drinks. Low phosphate concentrations are found in drinking water to which it is added in some areas in order to reduce lead solubility.
Physikalische Eigenschaften
Chemists refer to orthophosphoric acid as phosphoric acid, which is the IUPAC name for this compound. The prefix “ortho” is used to distinguish the acid from other phosphoric acids, which are generally called polyphosphoric acids. Orthophosphoric acid is a nontoxic, rather weak triprotic acid. When pure, it is a solid at STP. Orthophosphoric acid is a very polar molecule which makes it highly soluble in water. The valence state of phosphorous in orthophosphoric acid and other phosphoric acids is ＋5. Triprotic means that the orthophosphoric acid molecule can dissociate up to three times, producing a hydrogen cation, H⁺, each time.
Occurrence
Phosphoric acid is a natural constituent of many fruits and their juices.
History
Phosphoric acid was produced but not identified by alchemists in ancient times. It derives its name from the element phosphorus, which was discovered in 1669 by Henning Brand (1630 1710).Scheele subsequently isolated phosphorus from bone ash and produced phosphoric acid by reacting phosphorus and nitric acid. Scheele's method replaced bone as the main source of phosphorus rather than urine.
John Bennett Lawes (1814 1900) patented a process in 1841 of making superphosphate from bones and later extended his process to phosphates obtained from rock. Superphosphates are made by treating Ca3(PO4)2 with sulfuric acid to make more soluble calcium hydrogen phosphates: Ca3(PO4)2 + 2H2SO4 Ca(H2PO4)2 + 2CaSO4. In this reaction Ca(H2PO4)2 is monobasic calcium phosphate, which is also called superphosphate. Calcium hydrogen phosphates (superphosphates) are more water soluble and therefore more readily available to plants.
Verwenden
In the manufacture of superphosphates for fertilizers, other phosphate salts, polyphosphates, detergents. Acid catalyst in making ethylene, purifying hydrogen peroxide. As acidulant and flavor, synergistic antioxidant and sequestrant in food. Pharmaceutic aid (solvent). In dental cements; process engraving; rustproofing of metals before painting; coagulating rubber latex; as analytical reagent.
Verwenden
Phosphoric Acid is an acidulant that is an inorganic acid produced by burning phosphorus in an excess of air, producing phosphorus pentoxide which is dissolved in water to form orthophosphoric acid of varying concentrations. it is a strong acid which is soluble in water. the acid salts are termed phosphates. it is used as a flavoring acid in cola and root beer beverages to provide desirable acidity and sourness. it is used as a synergistic antioxidant in vegetable shorten- ings. in yeast manufacture, it is used to maintain the acidic ph and provide a source for phosphorus. it also functions as an acidulant in cheese. it is also termed orthophosphoric acid.
Verwenden
Phosphoric acid is second only to sulfuric acid as an industrial acid and consistently ranksin the top 10 chemicals used globally.States, but it is used in a number of other applications. Phosphateswere used as builders and water softeners. A builder is a substance added to soaps or detergentsto increase their cleansing power.
Phosphoric acid is used as an intermediate in the production of animal feed supplements,water treatment chemicals, metal surface treatments, etching agent, and personal care productssuch as toothpaste. It is used as a catalyst in the petroleum and polymer industry. Phosphoricacid is used in food as a preservative, an acidulant, and flavor enhancer; it acidifies carbonateddrinks such as Coca Cola and Pepsi, giving them a tangy flavor. Phosphoric acid is used as arust remover and metal cleaner. Naval Jelly is approximately 25% phosphoric acid. Other usesfor phosphoric acid include opacity control in glass production, textile dyeing, rubber latexcoagulation, and dental cements.
Verwenden
Phosphoric acid (H₃PO₄) is the most important oxoacid of phosphorus and its main use is in the manufacture of fertilisers.
Within the human body, phosphate is the main phosphorus-containing compound. Phosphate is an inorganic compound and is the salt of phosphoric acid. It can form organic esters with a variety of compounds and these are important in many biochemical processes. Phosphate has the empirical formula PO₄^3-. It is a tetrahedral molecule, where the central phosphorus atom is surrounded by four oxygen atoms.
In biological systems, phosphate is often found either as the free ion (inorganic phosphate) or as an ester after reaction with organic compounds (often referred to as organic phosphates). Inorganic phosphate (mostly denoted as Pi) is a mixture of HPO₄^2- and H₂PO₄^- at physiological pH.
synthetische
Low-purity technical grade phosphoric acid for use in fertilizers is produced from phosphate rocks by digestion with concentrated sulfuric acid. The apatite types, primarily consisting of calcium phosphate phosphate rocks, are used: Ca3(PO4)2 + 3H2SO4 + 6H2O → 2H3PO4 + 3(CaSO4•2H2O)
The insoluble calcium sulfate slurry is filtered out. Acid from this wet process is impure but can be purified by various methods. Purification steps involve precipitation, solvent extraction, crystallization, and ion exchange techniques.
Phosphoric acid also can be made by many different methods. Dissolution of phosphorus pentoxide in water and boiling yields phosphoric acid. Pure phosphoric acid can be obtained by burning phosphorus in a mixture of air and steam:
P4 (l) + 5O2 (g) →P4O10 (s)
P4O10 (s) + H2O (g) → 4H3PO4 (l)
The acid also may be prepared by heating violet phosphorus with 33% nitric acid:
4P + 10HNO3 + H2O → 4H3PO4 + 5NO ↑ + 5NO2 ↑
or by heating red phosphorus with nitric acid (1:1). The overall equation is:
P + 3HNO3 → H3PO4 + NO + 2NO2
Vorbereitung Methode
The major sources of H3PO4 traditionally have been mineral deposits of phosphate rock. Mining operations are extensive in a number of locations, including the United States (Florida), the Mediterranean area, and Russia, among others. The major constituent of most phosphate rocks is fluorapatite, 3Ca3(PO4)2·CaF2. The supply of high-grade phosphates, the raw material of choice for producing high-purity phosphoric acid by the wet process, is rapidly decreasing in some areas.
Two major methods are utilized for the production of phosphoric acid from phosphate rock. The wet process involves the reaction of phosphate rock with sulfuric acid to produce phosphoric acid and insoluble calcium sulfates. Many of the impurities present in the phosphate rock are also solubilized and retained in the acid so produced. While they are of no serious disadvantage when the acid is to be used for fertilizer manufacture, their presence makes the product unsuitable for the preparation of phosphatic chemicals.
In the other method, the furnace process, phosphate rock is combined with coke and silica and reduced at high temperature in an electric furnace, followed by condensation of elemental phosphorus. Phosphoric acid is produced by burning the elemental phosphorus with air and absorbing the P2O5 in water. The acid produced by this method is of high purity and suitable for nearly all uses with little or no further treatment.
Vorbereitung Methode
The majority of phosphoric acid is made by digesting phosphate rock (essentially tricalcium phosphate) with sulfuric acid; the phosphoric acid is then separated by slurry filtration. Purification is achieved via chemical precipitation, solvent extraction, crystallization, or ion exchange.
Definition
ChEBI: Phosphoric acid is a phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom. It has a role as a solvent, a human metabolite, an algal metabolite and a fertilizer. It is a conjugate acid of a dihydrogenphosphate and a phosphate ion.
Trademarks
Pharmaceutic aid (solvent).
Allgemeine Beschreibung
A clear colorless liquid or transparent crystalline solid. The pure solid melts at 42.35°C and has a density of 1.834 g / cm3. Liquid is usually an 85% aqueous solution. Shipped as both a solid and liquid. Corrosive to metals and tissue. Used in making fertilizers and detergents and in food processing.
Air & Water Reaktionen
Soluble in water with small release of heat.
Reaktivität anzeigen
Phosphorous acid reacts exothermically with bases. May react with active metals, including such structural metals as aluminum and iron, to release hydrogen, a flammable gas. Can initiate the polymerization of certain classes of organic compounds. Reacts with cyanide compounds to release gaseous hydrogen cyanide. May generate flammable and/or toxic gases in contact with dithiocarbamates, isocyanates, mercaptans, nitrides, nitriles, sulfides, and strong reducing agents. Forms explosive mixture with nitromethane. Reacts violently with sodium tetrahydroborate. In the presence of chlorides can corrode stainless steel to form explosive hydrogen gas. Emits toxic and irritating fumes of oxides of phosphorus when heated to decomposition [Lewis, 3rd ed., 1993, p. 1029].
Hazard
Phosphoric acid is water soluble and absorbs oxygen readily, and the specific gravity is 1.89, which is heavier than water. It is toxic by ingestion and inhalation and an irritant to the skin and eyes, with a TLV of 1 mg/m3 of air. The four-digit UN identification number is 1805. The NFPA 704 designation is health 3, flammability 0, and reactivity 0. The primary use of phosphoric acid is in chemical analysis and as a reducing agent.
Health Hazard
Phosphoric acid is less corrosive and hazardous than is concentrated sulfuric or nitricacid. Its concentrated solutions are irritantsto the skin and mucous membranes. Thevapors (P2O5 fumes) can cause irritation tothe throat and coughing but could be tolerated at <10 mg/m³.The acute oral toxicity in rats is reported tobe low, the LD50 value being 1530 mg/kg(NIOSH 1986).
Brandgefahr
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.
Flammability and Explosibility
Non flammable
Pharmazeutische Anwendungen
Phosphoric acid is widely used as an acidifying agent in a variety of pharmaceutical formulations. It is used in pharmaceutical products as part of a buffer system when combined with a phosphate salt such as sodium phosphate, monobasic or dibasic. It is also widely used in food preparations as an acidulant, flavor, and synergistic antioxidant (0.001–0.005%) and sequestrant.
Therapeutically, dilute phosphoric acid has been used welldiluted in preparations used in the treatment of nausea and vomiting. Phosphoric acid 35% gel has also been used to etch tooth enamel and to enhance delivery of drugs through the nail.
) Nanosized hydroxyapatite powder was made by combining phosphoric acid with egg shells.
Landwirtschaftliche Anwendung
Phosphoric acid (H₃PO₄), also known as orthophosphoric acid, is the most significant source of phosphate fertilizers. Phosphoric acid based fertilizers mainly include ammonium phosphate, diammonium phosphate and monoammonium phosphate.
Phosphoric acid is deliquescent and commercially the most important derivative of phosphorus, accounting for over 90% of the phosphate rock mined. The white rhombic solid is highly soluble in water and ethanol, and the concentrated aqueous solution is generally available for use.
Phosphoric acid is used in several industries other than the fertilizer industry. Most elemental phosphorus is converted into phosphoric acid for non-fertilizer use. There are two basic processes for the production of phosphoric acid.
Metaphosphoric acid is obtained by heating phosphoric acid until dense white fumes begin to appear. The product is highly deliquescent and glassy in appearance. Its salts are known as metaphosphates. Orthophosphoric acid is the most common and is used as an important phosphate ingredient in commercial fertilizers.
Industrielle Verwendung
As a cleanser for metals, phosphoric acid produces a light etch on steel, aluminum, or zinc, which aids paint adhesion. Deoxidine is a phosphoric acid cleanser for metals. Nielite D is phosphoric acid with a rust inhibitor, used as a nonfuming pickling acid for steel. Albrite is available in 75, 80, and 85% concentrations in food and electronic grades, both high-purity specifications. DAB and Phosbrite are called Bright Dip grades, for cleaning applications. Phosphoric anhydride, or phosphorus pentoxide, P2O5, is a white, water-soluble powder used as a dehydrating agent and also as an opalizer for glass. It is also used as a catalyst in asphalt coatings to prevent softening at elevated temperatures and brittleness at low temperatures.
Biochem/physiol Actions
Phosphoric acid is commonly used in fertilizer industry. It is also used in the manufacture of insecticide and pesticide.
Sicherheitsprofil
Human poison by ingestion. Moderately toxic by skin contact. A corrosive irritant to eyes, skin, and mucous membranes, and a systemic irritant by inhalation. A common air contaminant. A strong acid. Mixtures with nitromethane are explosive. Reacts with chlorides + stainless steel to form explosive hydrogen gas. Potentially violent reaction with solum tetrahydroborate. Dangerous; when heated to decomposition it emits toxic fumes of POx
Sicherheit(Safety)
In the concentrated form, phosphoric acid is an extremely corrosive and harmful acid. However, when used in pharmaceutical formulations it is usually very diluted and is generally regarded as an essentially nontoxic and nonirritant material.
The lowest lethal oral dose of concentrated phosphoric acid in humans is reported to be 1286 mL/kg.
(rabbit, skin): 2.74 g/kg
(rat, oral): 1.53 g/kg
Synthese
The elemental phosphorus is burned to produce phosphorous pentoxide (P2O5), which is then hydrated. The heat is then removed and the phosphoric acid (H3PO4) is collected as a fine mist. Another important source of phosphoric acid is from phosphate rocks by treatment with sulfuric acid; this is the so-called wet-acid process. The synthesis of pure phosphoric acid involves several steps including a time-consuming, expensive step, the sublimation of white phosphorus.
mögliche Exposition
Phosphoric acid is used in the manufacture of fertilizers, phosphate salts; polyphosphates, detergents, activated carbon; animal feed; ceramics, dental cement; pharmaceuticals, soft drinks; gelatin, rust inhibitors; wax, and rubber latex. Exposure may also occur during electropolishing, engraving, photoengraving, lithographing, metal cleaning; sugar refining; and water-treating.
Carcinogenicity
Phosphoric acid was not mutagenic in bacterial assays.
Lager
When stored at a low temperature, phosphoric acid may solidify, forming a mass of colorless crystals, comprising the hemihydrate, which melts at 28°C. Phosphoric acid should be stored in an airtight container in a cool, dry place. Stainless steel containers may be used.
Versand/Shipping
UN1805 Phosphoric acid solution, Hazard class: 8; Labels: 8-Corrosive material. UN3543 Phosphoric acid solid, Hazard class: 8; Labels: 8-Corrosive material.
Inkompatibilitäten
Phosphoric acid is a strong acid and reacts with alkaline substances. Mixtures with nitromethane are explosive.
Waste disposal
Add slowly to solution of soda ash and slaked lime with stirring, then flush to sewer with large volumes of water.
Regulatory Status
GRAS listed. Accepted as a food additive in Europe. Included in the FDA Inactive Ingredients Database (infusions, injections, oral solutions, topical creams, lotions, ointments and solutions, and vaginal preparations). Included in nonparenteral and parenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Phosphoric acid Upstream-Materialien And Downstream Produkte

Orthophosphorsure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

7664-38-2, Phosphoric acid Verwandte Suche:

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