Chroman-4-on

Bezeichnung:Chroman-4-on

CAS-Nr491-37-2

Englisch Name:4-Chromanone

CBNumberCB4191157

SummenformelC9H8O2

Molgewicht148.16

MOL-Datei491-37-2.mol

Synonyma

Chroman-4-on

Chroman-4-on physikalisch-chemischer Eigenschaften

Schmelzpunkt	35-38 °C(lit.)
Siedepunkt	127-128 °C13 mm Hg(lit.)
Dichte	1.1291
Brechungsindex	n20/D 1.575(lit.)
Flammpunkt	>230 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
Aggregatzustand	Crystalline Powder, Crystals or Low Melting Mass
Farbe	White to yellow
Wasserlöslichkeit	Slightly soluble in water.
BRN	124652
InChIKey	MSTDXOZUKAQDRL-UHFFFAOYSA-N
LogP	1.990 (est)
CAS Datenbank	491-37-2(CAS DataBase Reference)
NIST chemische Informationen	4H-1-Benzopyran-4-one, 2,3-dihydro-(491-37-2)
EPA chemische Informationen	4H-1-Benzopyran-4-one, 2,3-dihydro- (491-37-2)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	33-36/37/38
S-Sätze:	24/25-36-26
WGK Germany	2
RTECS-Nr.	DJ2981225
TSCA	Yes
HazardClass	IRRITANT
HS Code	29329990

Gefahreninformationscode (GHS)

4-Chromanone Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R33:Gefahr kumulativer Wirkungen.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
white to light yellow crystal powder
Verwenden
4-Chromanone has been used to study the substrate specificity and catalytic ability of 4-hydroxyacetophenone monooxygenase isolated from Pseudomonas fluorescens ACB
Definition
ChEBI: 4-Chromanone is a member of chromones.
Synthesis Reference(s)
The Journal of Organic Chemistry, 48, p. 5160, 1983 DOI: 10.1021/jo00174a003
läuterung methode
It has been recrystallised from pet ether, or purified by dissolving in *C6H6 washing with H2O, drying (MgSO4), evaporating and distilling in a vacuum, then recrystallising the residue. The liquid has a pleasant lemon-like odour. The semicarbazone has m 227o. [Loudon & Razdan J Chem Soc 4299 1954.] The oxime is prepared from 3g of chromanone, 3g NH2OH.HCl in EtOH (50mL), 6g K2CO3 and refluxed on a water bath for 6hours. The solution is poured into H2O, the solid is filtered off, dried and dissolved in hot *C6H6 which on addition of pet ether yields the oxime as glistening needles m 140o. Hydrolysis of this gives very pure chromanone. The benzal derivative is prepared from 3g of chromanone and 4g PhCHO in 50mL EtOH, heated to boiling, 10mL of conc HCl are added dropwise and set aside for several days. The derivative separates and is recrystallised from EtOH to give yellow needles, m 112o [Powell J Am Chem Soc 45 2711 1923]. Reaction with Pb(OAc)4 yields the 3-acetoxy derivative m 74o (from pet ether + trace of EtOAc) [Cavill et al. J Chem Soc 4573 1954, Beilstein 17/10V 14].

4-Chromanone Upstream-Materialien And Downstream Produkte

Chroman-4-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

491-37-2, 4-Chromanone Verwandte Suche:

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