2,5-Dimethylhexan-2,5-diol

Bezeichnung:2,5-Dimethylhexan-2,5-diol

CAS-Nr110-03-2

Englisch Name:2,5-Dimethyl-2,5-hexanediol

CBNumberCB3335426

SummenformelC8H18O2

Molgewicht146.23

MOL-Datei110-03-2.mol

Synonyma

2,5-Dimethylhexan-2,5-diol

2,5-Dimethylhexan-2,5-diol physikalisch-chemischer Eigenschaften

Schmelzpunkt	86-90 °C (lit.)
Siedepunkt	214-215 °C (lit.)
Dichte	0,898 g/cm³
Dampfdruck	0.18Pa at 20℃
Brechungsindex	1.4429 (estimate)
Flammpunkt	126 °C
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	15.07±0.29(Predicted)
Aggregatzustand	Crystalline Flakes
Farbe	White
Geruch (Odor)	mild camphor
Wasserlöslichkeit	SOLUBLE
BRN	1361437
InChIKey	ZWNMRZQYWRLGMM-UHFFFAOYSA-N
LogP	0.21 at 23℃
CAS Datenbank	110-03-2(CAS DataBase Reference)
NIST chemische Informationen	2,5-Hexanediol, 2,5-dimethyl-(110-03-2)
EPA chemische Informationen	2,5-Hexanediol, 2,5-dimethyl- (110-03-2)

Sicherheit

S-Sätze:	22-24/25
WGK Germany	3
TSCA	Yes
HS Code	29053980
Giftige Stoffe Daten	110-03-2(Hazardous Substances Data)

Gefahreninformationscode (GHS)

2,5-Dimethyl-2,5-hexanediol Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
Colorless or white crystalline flakes. M.P. 93°C. B.P. 213°C. Soluble in water (20°C 140g/L), miscible with alcohol and most oils. Faint, camphorlike odor.
Verwenden
2,5-Dimethyl-2,5-hexanediol is used as an intermediate in the preparation of 2.5-Dimethyl-2.5-bis(tertbutyl-peroxy)hexane to produce polyethylene copolymers and polyethylene rubbers. It is also could be used to prepared nickel-containing Complex Reducing Agents (termed NiCRA)[1].
Verwenden
2,5-Dimethyl-2,5-hexanediol was used in the synthesis of six- and seven-membered heterocyclic boron compounds containing intramolecular N-B bond.
synthetische
The raw materials 2,5-Dimethyl-3-hexyne-2,5-diol (37.4 g, 263 mmol), ethyl acetate (60 mL), and Pd/C catalyst (0.285 g, 2.63 mmol, 1 mol %) were added to an autoclave. The hydrogen gas was slowly added to 10 bar. When the hydrogenation reaction was performed for 12 hours and then removed the hydrogen gas. Finally, 2,5-Dimethyl-2,5-hexanediol is obtained by purification.
Synthesis Reference(s)
Synthesis, p. 165, 1981 DOI: 10.1055/s-1981-29377
Allgemeine Beschreibung
2,5-Dimethyl-2,5-hexanediol on heteropoly acid catalyzed dehydration yields cyclic ethers via stereospecific intramolecular S_N2 mechanism. It reacts with nitriles in concentrated sulfuric acid to yield Δ¹-pyrrolines.
läuterung methode
Purify the diol by fractional crystallisation. Then the diol is dissolved in hot acetone, treated with activated charcoal, and filtered while hot. The solution is cooled and the diol is filtered off and washed well with cold acetone. The crystallisation process ia repeated several times, and the crystals are dried under a vacuum in a freeze-drying apparatus [Goates et al. J Chem Soc, Faraday Trans 1 78 3045 1982]. [Beilstein 1 IV 2600.]
Einzelnachweise
[1] Feghouli G, et al. Activation of reducing agents. Sodium hydride containing complex reducing agents 29. Epimerization of alcohols by nickel-containing complex reducing agents (NiCRA). Tetrahedron Letters, 1988; 9: 285–290.

2,5-Dimethyl-2,5-hexanediol Upstream-Materialien And Downstream Produkte

2,5-Dimethylhexan-2,5-diol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

110-03-2, 2,5-Dimethyl-2,5-hexanediol Verwandte Suche:

Send Inquriy