Alverindihydrogencitrat

Alverine citrate Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  White or almost white, crystalline powder.

• Originator

  Alverine citrate,Kemikos

• Verwenden

  anticholinergic

• Verwenden

  An adrenergic-β3 receptor agonist. Antispasmodic.

• Verwenden

  Used for studies of pharmacological activity including:
  
  • Synergism with fluconazole against Saccharomyces cerevisiae and Candida albicans
  • Efficacy of combination with simeticone on abdominal pain associated with irritable bowel syndrome
  • Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis
  • Drug effects viewed from a signal transduction network perspective
  • Enhanced cytotoxic effect of proteasome inhibitor MG132
  • Mechanism of action on phasic smooth muscles

• Definition

  ChEBI: The citrate salt of alverine, resulting from the reaction of equimolar amounts of alvarine and citric acid. An antispasmodic that acts directly on intestinal and uterine smooth muscle, it is used in the treatment of irritable bowel syndrome.

• Manufacturing Process

  2 Methods of producing of alverine:
  1. 3-Phenylpropylchloride reacted with ethylamine in the presence potassium hydroxide and N-ethyl-3,3'-diphenyldipropylamine (alverine) was obtained.
  2. 3-Phenylpropenal reacted with ethylamine in the presence hydrogen and Pt as catalyst and BaSO4 and N-ethyl-3,3'-diphenyldipropylamine (alverine) was obtained.
  In practice it is usually used as citrate.

• Therapeutic Function

  Anticholinergic, Spasmolytic

Alverine citrate Upstream-Materialien And Downstream Produkte

Alverindihydrogencitrat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(188)Suppliers

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