Trikaliumcitrat

Potassium Citrate Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  Potassium citrate is a potassium salt of citric acid with the molecular formula C₆H₅K₃O₇. It is a white, slightly hygroscopic crystalline powder. It is odorless with a saline taste.
  As a food additive, potassium citrate is used to regulate acidity and is known as E number E332. Medicinally, it may be used to control kidney stones derived from either uric acid or cystine.

• Chemische Eigenschaften

  Colorless or white crystals or powder; cooling, saline taste; odorless; deliquescent. Soluble in water and glycerol; almost insoluble in alcohol.

• Verwenden

  For use as an electrolyte replenisher and in the treatment of hypokalemia.

• Verwenden

  Potassium citrate is rapidly absorbed when given by mouth and is excreted in the urine. Since it is an alkaline salt it is effective in reducing the pain and frequency of urination when these are caused by highly acidic urine . It is used for this purpose in dogs and cats, but is chiefly employed as a non-irritating diuretic.
  Potassium citrate is an effective way to treat/manage gout and arrhythmia, if the patient is hypokalemic.
  It is widely used to treat urinary calculi (kidney stones) and is often used by patients with cystinuria .

• Verwenden

  potassium citrate is it acts as a buffer, maintaining product pH constant, a pH adjuster and a product stabilizer. This is a potassium salt.

• Definition

  ChEBI: The anhydrous form of the tripotassium salt of citric acid.

• Vorbereitung Methode

  Potassium citrate is produced by adding potassium bicarbonate or potassium carbonate to a solution of citric acid until effervescence ceases, filtering the solution and evaporating to granulation.

• Flammability and Explosibility

  Non flammable

• Industrielle Verwendung

  Potassium citrate is used in the United Kingdom as an over-the-counter drug for the relief from discomfort experienced in mild urinary-tract infections by increasing the urinary pH. It should be not given to men if they experience pain in the kidney area (risk of kidney stones) or if blood or pus is present in the urine. Also, patients with raised blood pressure or diabetes should avoid taking potassium citrate without consultation with their general practitioner (GP). Caution is generally advised to patients with renal impairment, cardiac problems and the elderly [3a].

• Sicherheitsprofil

  Poison by intravenous route. When heated to decomposition it emits toxic fumes of K2O.

• Vorsichtsmaßnahmen

  Potassium citrate is usually administered by mouth in dilute aqueous solution. This is because of its somewhat caustic effect on the stomach lining, and the potential for other mild health hazards.
  In states where non-prescription potassium citrate is legal, the maximum allowable over-the-counter (OTC) dose for elemental potassium is regulated by the FDA to be no more than 100 mg (approximately 3 % of the daily allowance ) . Pure potassium citrate contains 38.28 % potassium.

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