Methyl-(triphenylphosphoranyliden)acetat

Bezeichnung:Methyl-(triphenylphosphoranyliden)acetat

CAS-Nr2605-67-6

Englisch Name:Methyl (triphenylphosphoranylidene)acetate

CBNumberCB3248865

SummenformelC21H19O2P

Molgewicht334.35

MOL-Datei2605-67-6.mol

Synonyma

Methyl-(triphenylphosphoranyliden)acetat

Methyl-(triphenylphosphoranyliden)acetat physikalisch-chemischer Eigenschaften

Schmelzpunkt	168-172 °C (lit.)
Siedepunkt	165～170℃
Dichte	1.17±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
Löslichkeit	Acetonitrile (Slightly), Chloroform (Slightly)
Aggregatzustand	Powder
Farbe	White to off-white
Wasserlöslichkeit	insoluble
Sensitive	Air Sensitive
BRN	618430
InChI	InChI=1S/C21H19O2P/c1-23-21(22)17-24(18-11-5-2-6-12-18,19-13-7-3-8-14-19)20-15-9-4-10-16-20/h2-17H,1H3
InChIKey	NTNUDYROPUKXNA-UHFFFAOYSA-N
SMILES	C(OC)(=O)C=P(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1
CAS Datenbank	2605-67-6(CAS DataBase Reference)
EPA chemische Informationen	Acetic acid, (triphenylphosphoranylidene)-, methyl ester (2605-67-6)

Sicherheit

Kennzeichnung gefährlicher	T,Xi
R-Sätze:	36/37/38-25
S-Sätze:	22-24/25-36-26
WGK Germany	3
Hazard Note	Irritant
TSCA	TSCA listed
HS Code	29319090
Speicherklasse	11 - Combustible Solids

Gefahreninformationscode (GHS)

Methyl (triphenylphosphoranylidene)acetate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R25:Giftig beim Verschlucken.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
white to off-white powder
Verwenden
Wittig reagent for the two-carbon homologation of aldehydes to α,β-unsaturated esters. Also used in an efficient synthesis of pyrazoles via reaction with methyl diazoacetate in the presence of triethylamine.
Verwenden
1. (Methoxycarbonylmethylene)triphenylphosphorane is used in olefination reactions. Wittig reagent for the two-carbon homologation of aldehydes to α,β-unsaturated esters. it undergoes the Wittig reaction with aldehydes to give substituted methyl acrylates.
2. used in an efficient synthesis of pyrazoles via reaction with methyl diazoacetate in the presence of triethylamine.
3. It is used in the preparation of (triphenylphosphoranylidene)-ketene.
4. The Wittig reaction we performed in class involved the reaction of 2-nitrobenzaldehyde (1) with methyl (triphenylphosphoranylidene) acetate (2) to produce methyl (2E)-3-(2-nitrophenyl) acrylate (3) with a triphenylphosphine oxide (4) side product, and took place in a silica gel matrix to ensure even product dispersion for chromatography.
Verwenden
(Methoxycarbonylmethylene)triphenylphosphorane is used in olefination reactions. Further, it undergoes the Wittig reaction with aldehydes to give substituted methyl acrylates. It is used in the preparation of (triphenylphosphoranylidene)-ketene.
reaction suitability
reaction type: C-C Bond Formation
läuterung methode
Crystallise it by dissolving in it AcOH and adding pet ether (b 40-50o) to give colourless plates. UV max (A 1mm ): 222nm (865) and 268nm (116) [Isler et al. Helv Chim Acta 40 1242 1957]. [Beilstein 16 IV 977.]

Methyl (triphenylphosphoranylidene)acetate Upstream-Materialien And Downstream Produkte

Methyl-(triphenylphosphoranyliden)acetat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

2605-67-6, Methyl (triphenylphosphoranylidene)acetate Verwandte Suche:

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