Sevelamer carbonate

Gefahreninformationscode (GHS)

Sevelamer carbonate Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  Sevelamer carbonate (SC) is a non-absorbed phosphate binding crosslinked polymer, with the same polymeric structure as sevelamer hydrochloride, in which carbonate replaces chloride as the counterion. SC has been found to have the same safety and efficacy profile as Sevelamer HCl in HD patients.
  Sevelamer carbonate(Renvela) is a nonaluminum, non-calcium-basedphosphorus binder that traps phosphorus in the bowel through ion exchange and hydrogen binding. This drug replaced sevelamer hydrochloride(Renagel) and has an advantage of not generating an acid load, as its precursor, sevelamer hydrochloride, did. It also has the advantage of lowering LDL cholesterol due to gut binding of bile acids.

• Verwenden

  Control of serum phosphorus in patients with chronic kidney disease (phosphate binder).

• Verwenden

  Sevelamer Carbonate, a non-?absorbed polymer is an oral phosphate binder in patients with kidney failure. It is reported that Sevelamer Carbonate is less likely to cause hypercalcemia, low levels of PTH, and progressive coronary and aortic calcification in hemodialysis patients than calcium-?based phosphate binders.

Sevelamer carbonate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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