77341-67-4

108-30-5

2216-51-5

77341-67-4

Synthesis Example 1: Synthesis of 1-menthyl-(1-menthoxyethyl) succinate Synthesis of Compound 1: To a 100 mL autoclave, 10.00 g (63.99 mmol) of L-menthol and 6.40 g (63.96 mmol) of succinic anhydride were added, and the air in the autoclave was replaced with nitrogen. Subsequently, the mixture was stirred at 110°C for 8 hours. After completion of the reaction, it was cooled to room temperature and 100 mL of hexane was added to the reaction mixture. The precipitated crystals were filtered and the hexane phase of the filtrate was concentrated to give 16.61 g of 1-menthylsuccinic acid with purity >99.9%.