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Name Methylparaben
CAS 99-76-3
EINECS(EC#) 202-785-7
Molecular Formula C8H8O3
MDL Number MFCD00002352
Molecular Weight 152.15
MOL File 99-76-3.mol

Chemical Properties

Appearance white crystalline powder
Melting point  125-128 °C(lit.)
Boiling point  298.6 °C
density  1,46g/cm
vapor pressure  0.000005 hPa (20 °C)
FEMA  2710
refractive index  1.4447 (estimate)
Fp  280°C
storage temp.  0-6°C
solubility  ethanol: soluble0.1M, clear, colorless
form  Crystalline Powder
pka pKa 8.15(H2O,t =20.0) (Uncertain)
color  White to almost white
Odor odorless or faint char. odor, sl. burning taste
PH 5.8 (H2O, 20°C) (saturated solution)
Stability: Stable. Incompatible with strong oxidizing agents, strong bases.
Water Solubility  Slightly soluble in water.
FreezingPoint  131℃
Merck  14,6107
BRN  509801
Contact allergens
This substance is one of the parabens family. Parabens are esters formed by p-hydroxybenzoic acid and an alcohol. They are largely used as biocides in cosmetics and toiletries, medicaments, or food. They have synergistic power with other biocides. Parabens can induce allergic contact dermatitis, mainly in chronic dermatitis and wounded skin.
LogP 1.98 at 20℃
parabens is one of the most commonly used group of preservatives in the cosmetic, pharmaceutical, and food industries. Parabens provide bacteriostatic and fungistatic activity against a diverse number of organisms, and are considered safe for use in cosmetics, particularly in light of their low sensitizing potential. An evaluation of preservatives for use in leave-on cosmetic preparations lists parabens among the least sensitizing. The range of concentrations used in cosmetics varies between 0.03 and 0.30 percent, depending on the conditions for use and the product to which the paraben is added.
CAS DataBase Reference 99-76-3(CAS DataBase Reference)
NIST Chemistry Reference Benzoic acid, 4-hydroxy-, methyl ester(99-76-3)
EPA Substance Registry System 99-76-3(EPA Substance)

Safety Data

Hazard Codes  Xi,Xn
Risk Statements 
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
Safety Statements 
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S24/25:Avoid contact with skin and eyes .
WGK Germany  1
RTECS  DH2450000
Autoignition Temperature >600 °C
HS Code  29182930
Hazardous Substances Data 99-76-3(Hazardous Substances Data)

Hazard Information

Material Safety Data Sheet(MSDS)

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