55779-18-5

Pale Yellow Solid

Arprinocid,NANJING PHARMA

Arprinocide can be used as a Coccidiostat used in veterinary medicine.

ChEBI: Arprinocid is a member of 6-aminopurines.

To a solution of potassium t-butoxide in absolute ethanol slowly adding dry adenine. This mixture was stirred for about 2 h, and then 2-chloro-6- fluorobenzyl chloride was added over a period of about 4 h. The resulting mixture was heated to reflux with stirring and allowed to react for about 42 h, after which it was cooled to about 10°C. The crude product thus formed was isolated by filtration and then washed with ice cold ethanol and ice cold water to yield a 6-amino-9-(2-chloro-6-fluorobenzyl)purine.

Arpocox (Merck).

Coccidiostatic

The Journal of Organic Chemistry, 43, p. 960, 1978 DOI: 10.1021/jo00399a034