1623-08-1

white to slightly yellow powder

Eye irritant.

Dibenzyl phosphate and its derivatives are phosphorylation reagents; for example, di-p-tolyl phosphate is one of the key intermediates in the synthesis of fosapitant dimethylglucamine.

ChEBI: Dibenzyl phosphate is a dialkyl phosphate.

dibenzyl phosphate may be stored at 2–8 °C. It is incompatible with strong oxidizing agents. Avoid contact with skin and eyes.

[1] Bowers, S. G., Mahmud, T., & Floss, H. G. (2002). Biosynthetic studies on the α-glucosidase inhibitor acarbose: the chemical synthesis of dTDP-4-amino-4,6-dideoxy-α-d-glucose. Carbohydrate Research, 337 4, Pages 297-304. https://doi.org/10.1016/S0008-6215(01)00323-8 
[2] Zhang, S.-Y., Li, Q., He, G., Nack, W. A., & Chen*, G. (2014). Pd-Catalyzed Monoselective ortho-C–H Alkylation of N-Quinolyl Benzamides: Evidence for Stereoretentive Coupling of Secondary Alkyl Iodides. Journal of the American Chemical Society, 137 1, 531–539. https://doi.org/10.1021/ja511557h 
[3] Meyer, O., Ponaire, S., Rohmer, M., & Grosdemange-Billiard, C. (2006). Lewis Acid Mediated Regioselective Ring Opening of Benzylglycidol with Dibenzyl Phosphate: Short and Attractive Synthesis of Dihydroxyacetone Phosphate. Organic Letters, 8 19, 4347–4350. https://doi.org/10.1021/ol061748a 
[4] Veeneman, G. H., Broxterman, H. J. G., der Marel, G. A. van, & Boom, J. H. van. (1991). An approach towards the synthesis of 1,2-trans glycosyl phosphates via iodonium ion assisted activation of thioglycosides. Tetrahedron Letters, 32 43, Pages 6175-6178. https://doi.org/10.1016/0040-4039(91)80782-2