Supplier Related Products Identification Chemical Properties Safety Data Raw materials And Preparation Products Material Safety Data Sheet(MSDS) Questions And Answer Spectrum Detail Well-known Reagent Company Product Information
WebSite >  CAS DataBase List  > 156-38-7

156-38-7

Supplier Related Products Identification Chemical Properties Safety Data Raw materials And Preparation Products Material Safety Data Sheet(MSDS) Questions And Answer Spectrum Detail Well-known Reagent Company Product Information

Product Image

Identification

Name
4-Hydroxyphenylacetic acid
CAS
156-38-7
Synonyms
4-HYDROXYPHENYLACETIC ACID
AKOS 236-100
PHPA
P-HYDROPHENYLACETIC ACID
P-HYDROXYPHENYLACETIC ACID
RARECHEM AL BO 0188
(p-hydroxyphenyl)-aceticaci
4-carboxymethylphenol
4-Hydroxybenzeneacetic acid
4-hydroxy-benzeneaceticaci
4-hydroxybenzeneaceticacid
4-hydroxyphenylethanoicacid
Acetic acid, (p-hydroxyphenyl)-
ethanoicacid,4-hydroxyphenyl-
Parahydroxy phenylacetic acid
4-HYDROXYPHENYLACETIC ACID, FOR FLUORESC ENCE
4-HydroxyphenylacetidAcid
Benzeneacetic acid, 4-hydroxy-
2-(4-hydroxyphenyl)acetic acid
4-Hydroxyphenylacetic acid 98%
EINECS(EC#)
205-851-3
Molecular Formula
C8H8O3
MDL Number
MFCD00004347
Molecular Weight
152.15
MOL File
156-38-7.mol

Chemical Properties

Appearance
white to cream or light tan crystalline powder
mp 
148-151 °C(lit.)

BRN 
1448766
CAS DataBase Reference
156-38-7(CAS DataBase Reference)
NIST Chemistry Reference
Benzeneacetic acid, 4-hydroxy-(156-38-7)
EPA Substance Registry System
156-38-7(EPA Substance)

Safety Data

Hazard Codes 
Xi
Risk Statements 
R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Statements 
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S24/25:Avoid contact with skin and eyes .
WGK Germany 
3

RTECS 
AI2680000

Hazard Note 
Irritant
HS Code 
29182990

Raw materials And Preparation Products

Material Safety Data Sheet(MSDS)

Questions And Answer

Description
4-Hydroxyphenylacetic acid is an acetate derivative used in the acylation of phenols and amines1. It is an active component of Chinese herb Aster tataricus which had been widely used in China for the treatment of pulmonary diseases, HBV, and carcinoma. It is an active metabolite of amino acid metabolism. Study has also shown that it can attenuate inflammation and edema through suppressing hypertonic and hypoxic induction of HIF-1α in seawater aspiration-induced lung injury in rats. In chemical industry, it is an intermediate used to synthesize atenolol and 3, 4-dihydroxyphenylacetic acid.
Referrence
  1. Liu, Zhongyang, et al. "4-Hydroxyphenylacetic Acid Attenuated Inflammation and Edema via Suppressing HIF-1α in Seawater Aspiration-Induced Lung Injury in Rats." International Journal of Molecular Sciences 15.7(2014):12861-84.
  2. Ng, T.B.; Liu, F.; Lu, Y.; Cheng, C.H.; Wang, Z. Antioxidant activity of compounds from the medicinal herb Aster tataricus. Comp. Biochem. Physiol. 2003, 136, 109–115. 
  3. Du, L.; Mei, H.F.; Yin, X.; Xing, Y.Q. Delayed growth of glioma by a polysaccharide from Aster tataricus involve upregulation of Bax/Bcl-2 ratio, activation of caspase-3/8/9, and downregulation of the Akt. Tumour Biol. 2014, 35, 1819–1825.

Spectrum Detail

Well-known Reagent Company Product Information

SupplierMore