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Name Ethylene glycol
CAS 107-21-1
EINECS(EC#) 203-473-3
Molecular Formula C2H6O2
MDL Number MFCD00283324
Molecular Weight 62.07
MOL File 107-21-1.mol

Chemical Properties

Appearance Ethylene glycol is a colorless, viscous, hydroscopic liquid with a sweetish taste. Often colored fluorescent yellow-green when used in automotive antifreeze. Ethylene glycol is odorless and does not provide any warning of inhalation exposure to hazardous concentrations. The Odor Threshold in air is 25 ppm.
Melting point  -13 °C (lit.)
Boiling point  195-198 °C
density  1.113 g/mL at 25 °C(lit.)
vapor density  2.1 (vs air)
vapor pressure  0.08 mm Hg ( 20 °C)
refractive index  n20/D 1.431(lit.)
Fp  230 °F
storage temp.  2-8°C
solubility  water: miscible
form  Viscous Liquid
pka 14.22(at 25℃)
color  blue
Odor Odorless
PH 6-7.5 (100g/l, H2O, 20℃)
Relative polarity 0.79
explosive limit 3.2%(V)
Water Solubility  miscible
FreezingPoint  -11.5℃
Sensitive  Hygroscopic
λmax λ: 260 nm Amax: ≤0.03
λ: 280 nm Amax: ≤0.01
Merck  14,3798
BRN  505945
Exposure limits Ceiling limit in air for vapor and mist 50 ppm (~125 mg/m3) (ACGIH); TWA 10 mg/m3 (particulates) (MSHA).
LogP -1.36 at 25℃
CAS DataBase Reference 107-21-1(CAS DataBase Reference)
NIST Chemistry Reference 1,2-Ethanediol(107-21-1)
EPA Substance Registry System 107-21-1(EPA Substance)

Safety Data

Hazard Codes  Xn
Risk Statements 
R22:Harmful if swallowed.
R36:Irritating to the eyes.
Safety Statements 
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
RIDADR  UN 1219 3/PG 2
WGK Germany  3
RTECS  KW2975000
Autoignition Temperature 752 °F
HS Code  29053100
Safety Profile
Human poison by ingestion. (Lethal dose for humans reported to be 100 mL.) Moderately toxic to humans by an unspecified route. Moderately toxic experimentally by ingestion, subcutaneous, intravenous, and intramuscular routes. Human systemic effects by ingestion and inhalation: eye lachrymation, general anesthesia, headache, cough, respiratory stimulation, nausea or vomiting, pulmonary, kidney, and liver changes. If ingested it causes initial central nervous system stimulation followed by depression. Later, it causes potentially lethal kidney damage. Very toxic in particulate form upon inhalation. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. A skin, eye, and mucous membrane irritant. Combustible when exposed to heat or flame; can react vigorously with oxidants. Moderate explosion hazard when exposed to flame. Iptes on contact with chromium trioxide, potassium permanganate, and sodium peroxide. Mixtures with ammonium dichromate, silver chlorate, sodium chlorite, and uranyl nitrate ipte when heated to 100°C. Can react violently with chlorosulfonic acid, oleum, H2SO4, HClO4, and Pass. Aqueous solutions may ignite silvered copper wires that have an applied D.C. voltage. To fight fire, use alcohol foam, water, foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazardous Substances Data 107-21-1(Hazardous Substances Data)
LD50 in rats, guinea pigs (g/kg): 8.54, 6.61 orally (Smyth); in mice (ml/kg): 13.79 orally (Bornmann)

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