General Description
Odorless colorless liquid or solid (depending upon temperature).
Reactivity Profile
1,4-BUTANEDIOL(110-63-4) is heat and light sensitive. This compound reacts with acid chlorides, acid anhydrides and chloroformates. 1,4-BUTANEDIOL(110-63-4) also reacts with oxidizing agents and reducing agents. 1,4-BUTANEDIOL(110-63-4) is incompatible with isocyanates and acids. 1,4-BUTANEDIOL(110-63-4) is also incompatible with peroxides, perchloric acid, sulfuric acid, hypochlorous acid, nitric acid, caustics, acetaldehyde, nitrogen peroxide and chlorine.
Air & Water Reactions
Highly flammable. This chemical is hygroscopic. Water soluble.
Hazard
Toxic by ingestion.
Health Hazard
Ingestion of large amounts needed to produce any symptoms.
Definition
ChEBI: Butane-1,4-diol is a butanediol that is butane in which one hydrogen of each of the methyl groups is substituted by a hydroxy group. A colourless, water-miscible, viscous liquid at room temperature (m.p. 16℃) with a high boiling point (230℃), it is mainly used for the production of other organic chemicals, particularly the solvent oxolane (also known as tetrahydrofuran or THF). It has a role as a neurotoxin, a protic solvent and a prodrug. It is a butanediol and a glycol.
Fire Hazard
Nonflammable liquid, flash point (open cup)
121°C.
Solubility in water
1,4-Butanediol is soluble in water, alcohols, esters, ketones, glycol ethers and glycol ether acetates
(Butanediols, Butenediol, and Butynediol).
Purification Methods
Distil the glycol and store it over Linde type 4A molecular sieves, or crystallise it twice from anhydrous diethyl ether/acetone, and redistil it. It has been recrystallised from the melt and doubly distilled in vacuo in the presence of Na2SO4. [Beilstein 1 IV 2515.]
