ChemicalBook Product Catalog Organic Chemistry Carboxylic acids and derivatives 4-Hydroxybutyl acrylate

4-Hydroxybutyl acrylate

Product Name4-Hydroxybutyl acrylate
CAS2478-10-6
MFC7H12O3
MW144.17
EINECS219-606-3
MOL File2478-10-6.mol

Chemical Properties

Melting point	-112°C
Boiling point	95 °C/0.1 mmHg (lit.)
Density	1.041 g/mL at 25 °C (lit.)
vapor pressure	0.5Pa at 20℃
refractive index	n20/D 1.452(lit.)
Flash point	>230 °F
storage temp.	2-8°C
pka	14.99±0.10(Predicted)
form	clear liquid
color	Colorless to Almost colorless
Water Solubility	soluble
FreezingPoint	-112
BRN	1756545
Exposure limits	ACGIH: TWA 5 mg/m3 NIOSH: TWA 5 mg/m3
InChI	1S/C7H12O3/c1-2-7(9)10-6-4-3-5-8/h2,8H,1,3-6H2
InChIKey	NDWUBGAGUCISDV-UHFFFAOYSA-N
SMILES	OCCCCOC(=O)C=C
LogP	0.77 at 25℃
CAS DataBase Reference	2478-10-6(CAS DataBase Reference)
NIST Chemistry Reference	4-Hydroxybutyl acrylate(2478-10-6)
EPA Substance Registry System	4-Hydroxybutyl acrylate (2478-10-6)

Safety Information

Hazard Codes	Xn,N,Xi
Risk Statements	20/21/22-36/37/38-51/53
Safety Statements	26-37/39-38-61-36/37/39-29
RIDADR	2922
WGK Germany	3
F	10
TSCA	TSCA listed
HazardClass	8
PackingGroup	II
HS Code	29161290
Storage Class	10 - Combustible liquids
Hazard Classifications	Acute Tox. 4 Oral Eye Dam. 1 Skin Irrit. 2 Skin Sens. 1

MSDS

Provider	Language
ACROS	English
SigmaAldrich	English
ALFA	English

Usage And Synthesis

Preparation

4-Hydroxybutylacrylate can be prepared by a condensation reaction of acryloyl chloride and butanediol compounds. It should be noted that this reaction requires strict control of the stoichiometric ratio to prevent the diacylation side reaction of butanediol.

Chemical Properties

clear liquid

Uses

Hydroxybutyl acrylate was one of the monomers utilized in the preparation of poly(2-hydroxy-3-phenoxypropylacrylate, 4-hydroxybutyl acrylate, dibutyl maleate) membranes.

General Description

4-Hydroxybutyl acrylate (HBA) can be synthesized by the esterification of acrylic acid with 1, 4 butanediol over a catalyst such as Amberlyst 15. 4-Hydroxybutyl acrylate (HBA) exhibits properties such as luster, chemical and scratch resistance. HBA monomers may be used as one of the constituents for the fabrication of a membrane system for controlled release of transdermal drug delivery system.

Flammability and Explosibility

Non flammable

storage

In order to prevent polymerization, 4-Hydroxybutyl Acrylate (4-HBA) must always be stored under air and never under inert gases. The presence of oxygen is required for the stabilizer to function effectively. In order to minimize the likelihood of overstorage, the storage procedure should strictly follow the “first-in-first-out” principle. For extended storage periods over 4 weeks, it is advisable to replenish the dissolved oxygen content. The storage temperature for 4-Hydroxybutyl Acrylate (4-HBA) should not exceed 25 °C. The preferred construction material for tanks and pipes is stainless steel. Carbon steel is also acceptable, although the formation of rust may be a problem with product quality (color). Iron(III)-ions are a weak polymerization initiator. If carbon steel is used, special procedures should be used to prepare the tank.

4-Hydroxybutyl acrylate

Chemical Properties

Safety Information

MSDS

Usage And Synthesis

Preparation Products And Raw materials

4-Hydroxybutyl acrylate Supplier

4-Hydroxybutyl acrylate manufacturers

Related Product Information