Chemical Properties
4-Methoxyacetophenone occurs in anise oil. It forms white crystals
(mp 38°C) with a sweet odor, reminiscent of hawthorn. 4-Methoxyacetophenone
is prepared by Friedel–Crafts acetylation of anisole. A modern process uses
??-zeolites as Friedel–Crafts catalysts in combination with a continuous flow technology.
4-Methoxyacetophenone is used in soap perfumes
Chemical Properties
WHITE CRYSTALS OR CRYSTALLINE POWDER
Chemical Properties
Yellowish-white crystals with an odor similar to that of p-methylacetopheneone, suggestive of hawthorn and floral note
of heliotrope, possessing a bitter and unpleasant taste. Useful in vanilla, nut, tobacco and butter flavors
Occurrence
Reported found in European cranberry (Vaccinium oxycoccus L.), guava fruit (Psidium guajava L.), Vitis
labrusca L., tomato, anise (Pimpinella anisum L.), mentha oils, grilled and roasted beef, sherry, cloudberry (Rubus chamaemorus
L.), salted and pickled plums, Illicium verum and black chokeberry (Aronia melanocarpa ell.).
Definition
ChEBI: A member of the class of acetophenones that is acetophenone substituted by a methoxy group at position 4.
Preparation
From anisole and acetyl chloride in the presence of aluminum chloride and carbon disulfide; from anisole and acetic acid
in the presence of boron trifluoride.
Taste threshold values
Taste characteristics at 10 ppm: sweet, anisic, fruity, cherry with powdery vanilla nuances.
General Description
4′-Methoxyacetophenone undergoes biocatalytic enantioselective reduction using immobilized Rhodotorula sp. AS2.2241 cells to yield (S)-1-(4-methoxyphenyl) ethanol in a hydrophilic ionic liquid-containing co-solvent system.
Flammability and Explosibility
Notclassified
Purification Methods
Crystallise the ketone from diethyl ether/pet ether. [Beilstein 8 IV 340.]
