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2-Bromo-4'-methoxyacetophenone

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2-Bromo-4'-methoxyacetophenone Basic information
2-Bromo-4'-methoxyacetophenone Chemical Properties
  • Melting point:69-71 °C(lit.)
  • Boiling point:215.8°C (rough estimate)
  • Density 1.4921 (rough estimate)
  • refractive index 1.5500 (estimate)
  • storage temp. 2-8°C
  • form Crystals or Crystalline Powder
  • color Off-white to light brown
  • Water Solubility It is soluble in DMSO, water (partly miscible), most organic solvents, and methanol.
  • BRN 743112
  • InChIKeyXQJAHBHCLXUGEP-UHFFFAOYSA-N
  • CAS DataBase Reference2632-13-5(CAS DataBase Reference)
  • NIST Chemistry ReferenceEthanone, 2-bromo-1-(4-methoxyphenyl)-(2632-13-5)
Safety Information
MSDS
2-Bromo-4'-methoxyacetophenone Usage And Synthesis
  • Chemical Propertiesoff-white to light brown crystals or
  • Uses2-Bromo-4'-methoxyacetophenone is a α-haloacetophenone derivatives tested for inhibition of protein tyrosine phosphatases SHP-1 and PTP1B.
  • PreparationObtained by reaction of N-bromosuccinimide (NBS) with 4-methoxyacetophenone in the presence of trimethylsilyl trifluoromethanesulfonate (TMS-OTf) in acetonitrile at r.t. for 24 h (87%).
2-Bromo-4'-methoxyacetophenone Preparation Products And Raw materials
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