Натрий бензойнокислый
- английское имяSodium benzoate
- CAS №532-32-1
- CBNumberCB0698779
- ФормулаC7H5NaO2
- мольный вес144.10317
- EINECS208-534-8
- номер MDLMFCD00012463
- файл Mol532-32-1.mol
химическое свойство
| Температура плавления | >300 °C (lit.) |
| плотность | 1,44 g/cm3 |
| давление пара | 0Pa at 20℃ |
| FEMA | 3025 | SODIUM BENZOATE |
| Fp | >100°C |
| температура хранения | room temp |
| растворимость | H2O: 1 M at 20 °C, clear, colorless |
| пка | 4.03[at 20 ℃] |
| форма | Crystals, Granules, Flakes or Crystalline Powder |
| цвет | White |
| РН | 7.0-8.5 (25℃, 1M in H2O) |
| Запах | odorless |
| Растворимость в воде | soluble |
| Мерк | 14,8582 |
| БРН | 3572467 |
| Стабильность | Stable, but may be moisture senstive. Incompatible with strong oxidizing agents, alkalis, mineral acids. |
| ИнЧИКей | WXMKPNITSTVMEF-UHFFFAOYSA-M |
| LogP | 1.88 |
| FDA 21 CFR | 184.1733; 582.3733; 181.23; 310.545 |
| Вещества, добавляемые в пищу (ранее EAFUS) | SODIUM BENZOATE |
| Специальный комитет по веществам GRAS | Sodium Benzoate |
| Справочник по базе данных CAS | 532-32-1(CAS DataBase Reference) |
| Рейтинг продуктов питания EWG | 1-3 |
| FDA UNII | OJ245FE5EU |
| Код УВД | A16AX11 |
| Справочник по химии NIST | Sodium benzoate(532-32-1) |
| Система регистрации веществ EPA | Sodium benzoate (532-32-1) |
больше
| Коды опасности | Xi | |||||||||
| Заявления о рисках | 36/37/38-62-63-68-36 | |||||||||
| Заявления о безопасности | 24/25-36-26 | |||||||||
| WGK Германия | 1 | |||||||||
| RTECS | DH6650000 | |||||||||
| TSCA | Yes | |||||||||
| кода HS | 29163100 | |||||||||
| Банк данных об опасных веществах | 532-32-1(Hazardous Substances Data) | |||||||||
| Токсичность | LD50 orally in rats: 4.07 g/kg (Smyth, Carpenter) | |||||||||
| NFPA 704: |
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рисовальное письмо(GHS)
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рисовальное письмо(GHS)
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сигнальный язык
предупреждение
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вредная бумага
H319：При попадании в глаза вызывает выраженное раздражение.
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оператор предупредительных мер
P264：После работы тщательно вымыть кожу.
P280：Использовать перчатки/ средства защиты глаз/ лица.
P305+P351+P338：ПРИ ПОПАДАНИИ В ГЛАЗА: Осторожно промыть глаза водой в течение нескольких минут. Снять контактные линзы, если Вы ими пользуетесь и если это легко сделать. Продолжить промывание глаз.
P337+P313：Если раздражение глаз не проходит обратиться за медицинской помощью.
Натрий бензойнокислый химические свойства, назначение, производство
Описание
Sodium benzoate has the chemical formula NaC7H5O2; it is a widely used food preservative, with E number E211. It is the sodium salt of benzoic acid and exists in this form when dissolved in water. It can be produced by reacting sodium hydroxide with benzoic acid.Химические свойства
Sodium benzoate is a white crystalline solid. It is odorless and nonflammableВхождение
Benzoic acid occurs naturally in many plants and in animals. The salt is not found to occur naturally.Использование
sodium benzoate is a non-toxic, organic salt preservative that is particularly effective against yeast, with some activity against molds and bacteria. It is generally used in concentrations of 0.1 to 0.2 percent.Подготовка
Produced by the neutralization of benzoic acid with sodium bicarbonate, sodium carbonate or sodium hydroxide.Методы производства
Sodium benzoate is prepared by adding benzoic acid to a hot concentrated solution of sodium carbonate until effervescence ceases. The solution is then evaporated, cooled and allowed to crystallize or evaporate to dryness, and then granulated.Определение
sodium benzoate: An either colourlesscrystalline or white amorphouspowder, C6H5COONa, soluble inwater and slightly soluble in ethanol.It is made by the reaction of sodiumhydroxide with benzoic acid and isused in the dyestuffs industry and asa food preservative. It was formerlyused as an antiseptic.Общее описание
Sodium benzoate is a sodium salt of benzoic acid, that is freely soluble in water compared to benzoic acid. It is generally used as an antimicrobial preservative in cosmetics, food, and pharmaceuticals.Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Опасность
Use in foods limited to 0.1%.Фармацевтические приложения
Sodium benzoate is used primarily as an antimicrobial preservative in cosmetics, foods, and pharmaceuticals. It is used in concentrations of 0.02–0.5% in oral medicines, 0.5% in parenteral products, and 0.1–0.5% in cosmetics. The usefulness of sodium benzoate as a preservative is limited by its effectiveness over a narrow pH range.Sodium benzoate is used in preference to benzoic acid in some circumstances, owing to its greater solubility. However, in some applications it may impart an unpleasant flavor to a product. Sodium benzoate has also been used as a tablet lubricant at 2–5% w/w concentrations. Solutions of sodium benzoate have also been administered, orally or intravenously, in order to determine liver function.
Профиль безопасности
Poison by subcutaneous and intravenous routes. Moderately toxic by ingestion, intramuscular, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Mutation data reported. Larger doses of 8-10 g by mouth may cause nausea and vomiting. Small doses have little or no effect. Combustible when exposed to heat or flame. When heated to decomposition it emits toxic fumes of Na2O. See also BENZOIC ACID.Безопасность
In combination with ascorbic acid (vitamin C, E300), sodium benzoate and potassium benzoate form benzene, a known carcinogen. However, in most beverages that contain both, the benzene levels are below those considered dangerous for consumption. Heat, light and shelf life can affect the rate at which benzene is formed.Возможный контакт
Sodium benzoate is used as a food and feed additive, flavor, packaging material; pharmaceutical; preservative for food products and tobacco; anti-fungal agent; antiseptic, rust, and mildew inhibitor; intermediate in the manufacture of dyes. Used as a human hygiene biocidal product.хранилище
Aqueous solutions may be sterilized by autoclaving or filtration. The bulk material should be stored in a well-closed container, in a cool, dry place.Перевозки
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.Методы очистки
Crystallise it from EtOH (12mL/g). [Beilstein 9 IV 27.]Несовместимости
Dust may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.Регуляторный статус
GRAS listed. Accepted as a food additive in Europe. Included in the FDA Inactive Ingredients Database (dental preparations; IM and IV injections; oral capsules, solutions and tablets; rectal; and topical preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.Натрий бензойнокислый запасные части и сырье
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