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  • 橙花醇|T5645

橙花醇|T5645

Nerol
106-25-2
148 500mg 起订
上海 更新日期:2026-01-06

TargetMol中国(陶术生物)

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联系人:邵小姐
电话:021-021-33632979拨打
手机:15002134094 拨打
邮箱:marketing@targetmol.com

产品详情:

中文名称:
橙花醇
英文名称:
Nerol
CAS号:
106-25-2
品牌:
TargetMol
产地:
美国
保存条件:
Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
纯度规格:
98.59%
产品类别:
抑制剂
货号:
T5645

Product Introduction

Bioactivity

名称Nerol
描述Nerol (Neryl alcohol) is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmias in mammalian heart.
动物实验Guinea pigs were sacrificed by decapitation and hearts were removed and isolated left atrium mounted vertically in an organ baths containing Tyrode's solution of the following composition (mM): NaCl 120, KCl 2.7, MgCl2 0.9, NaHCO3 11.9, CaCl2 1.37, glucose 5.5, NaH2PO4 0.4, pH 7.4. The atria preparations were subsequently connected to Grass FI'-03 force displacement transducers to record changes in atrial contractile force. Each muscle was stretched to the length at which contractile force was maximal (1.0 gf). The atria were electrically paced at 1 Hz with pulses of 1.5 ms duration and stimulated by 70 V pulses. All preparations were allowed to equilibrate for 30 min until complete mechanical stabilization had been achieved. Nerol ( 97%) was freshly solubilized in 0.5% DMSO and cumulatively added to bath chambers. After each observation, muscles were washed several times and allowed to recover for 30 minutes until their mechanical function completely returned to control values. DMSO at this concentration did not show any significant effect on the variables measured (data not shown, n = 5).
体内活性Nerol主要通过阻断L型Ca2+通道减少Ca2+的流入,从而减轻了哺乳动物心脏中ouabain引发的心律失常的严重程度。
存储条件Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
溶解度DMSO : 45 mg/mL (291.73 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (12.97 mM), Sonication is recommended.
关键字ROS | ReactiveOxygenSpecies | Reactive Oxygen Species | Nerol | NEL | MitochondrialMetabolism | Mitochondrial Metabolism | mitochondrial | Inhibitor | inhibit | Fungal | EndogenousMetabolite | Endogenous Metabolite | dysfunction | Calcium | Apoptosis | Antifungal
相关产品Formamide | Guanidine hydrochloride | Glycerol | Aceglutamide | Calcium Propionate | Benzyl propionate | Levulinic acid | Sucrose | Gluconate Calcium | Thymidine | D(+)-Raffinose pentahydrate | Ethyl linoleate
相关库经典已知活性库 | 抗真菌库 | 古代经典名方目录分子库 | 苗药化合物库 | 抗衰老化合物库 | 风味天然产物库 | 中药单体化合物库 | 烟草单体化合物库 | 免疫/炎症分子化合物库 | 中药抗炎分子库 | 萜类天然产物库 | 抗感染天然产物库
br
橙花醇|||Neryl alcohol|||Cis-Geraniol|TargetMol

公司简介

上海陶术生物科技有限公司为美国Target Molecule Corp. ( Target Mol ) 在上海建立的全资子公司。我们与美国波士顿、德国慕尼黑的同事一起,为北美、欧洲和亚洲从事药物研发和生物学研究的科学家提供优质的产品和专业的服务。公司下设筛选事业部,化学事业部,生物事业部和新材料部。 从虚拟筛选到实体化合物分子供应;从商业化产品销售到个性化定制合成;从对明确靶点的分子筛选到对明确分子的多靶点筛选,从高通量筛选到化学结构优化,我们都可以满足您的科研用品及技术服务的需求。 经过在中国市场五年的精心耕耘,我们已成为筛选化合物领域优秀的供应商,为超过五百家学校和各类企业提供了品质卓越的小分子化合物和药物筛

成立日期 (13年)
注册资本 566.2651万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,试剂,定制,服务
主营行业 化学试剂,生物活性小分子

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