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D-Phenylalanine

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D-Phenylalanine Basic information
D-Phenylalanine Chemical Properties
  • Melting point:273-276 °C(lit.)
  • alpha 33.5 º (c=2, H2O)
  • Boiling point:293.03°C (rough estimate)
  • Density 1.1603 (rough estimate)
  • refractive index 34 ° (C=2, H2O)
  • storage temp. Store at RT.
  • pka2.2(at 25℃)
  • form Powder
  • color White to off-white
  • Water Solubility 27 g/L (20 ºC)
  • Merck 14,7271
  • BRN 2804068
  • Stability:Stable. Incompatible with strong oxidizing agents, acids, bases.
  • InChIKeyCOLNVLDHVKWLRT-MRVPVSSYSA-N
  • CAS DataBase Reference673-06-3(CAS DataBase Reference)
  • EPA Substance Registry SystemD-Phenylalanine (673-06-3)
Safety Information
  • Hazard Codes Xi,C
  • Risk Statements 34
  • Safety Statements 24/25-45-36/37/39-27-26
  • WGK Germany 3
  • RTECS AY7533000
  • Hazard Note Irritant
  • TSCA Yes
  • HS Code 29224995
  • ToxicityTDLo orl-hmn: 500 mg/kg/5W-I:GIT JACTDZ 1(3),124,82
MSDS
D-Phenylalanine Usage And Synthesis
  • DescriptionD-Phenylalanine, also known as D-alpha-Amino-beta-phenylpropionic acid, is a kind of non-proteinogenic amino acid. The biological function of D-phenylalanine remains unclear. However, it has certain anti-depressant, analgesic activities and pharmacological activity at niacin receptor II. The mechanism action of its analgesic activity seems to originate from its inhibition of enkephalin degradation by the carboxypeptidase A. It can also be used as pharmaceutical intermediates that are mainly used to treat, prevent osteoporosis, cardiovascular, diabetes and arterioscleros.
  • Chemical PropertiesWhite crystalline powder
  • Usesantidepressant
  • DefinitionChEBI: The D-enantiomer of phenylalanine.
  • General DescriptionNeedles or prisms.
  • Air & Water ReactionsWater soluble. Aqueous solutions are weakly acidic.
  • Reactivity ProfileD-alpha-Amino-beta-phenylpropionic acid may be light sensitive. D-alpha-Amino-beta-phenylpropionic acid reacts with strong oxidizing agents, acids and bases. . Act as weak acids in solution.
  • Fire HazardFlash point data for D-alpha-Amino-beta-phenylpropionic acid are not available, however D-alpha-Amino-beta-phenylpropionic acid is probably combustible.
  • Safety ProfileMildly toxic by intraperitoneal route. Human systemic effects by ingestion: nausea, hypermotility, diarrhea. When heated to decomposition it emits toxic fumes of NOx.
  • Referenceshttps://www.alfa.com/en/catalog/A10572/
    https://en.wikipedia.org/wiki/Phenylalanine
    Christianson, D. W., et al. "Binding of D-phenylalanine and D-tyrosine to carboxypeptidase A. " Journal of Biological Chemistry264.22(1989):12849-53.
D-Phenylalanine Preparation Products And Raw materials
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