1,3-Cyclohexanebis(methylamine)

1477-55-0

2579-20-6

The general procedure for the synthesis of 1,3-cyclohexanedimethylamine from 1,3-benzenedimethanamine is as follows: all hydrogenation reactions were carried out in a 100 mL Parr reactor equipped with a magnetically driven stirrer and an electric heater. First, 1,3-benzenedimethylamine, solvent, suitable catalyst and promoter were added to the reactor as required. Subsequently, the reactor was purged using N2 and then H2 and pressurized to about 2 MPa. Under stirring conditions, the reactor was heated to a set reaction temperature while H2 was replenished from the storage tank to maintain a constant pressure. During the reaction, the pressure change in the storage tank was monitored by a pressure sensor and a recorder to observe the reaction process. The reaction was considered complete when the consumption of H2 stopped. At the end of the reaction, the reactor was cooled to room temperature and the reaction mixture was collected. After removal of catalyst by filtration, the product mixture was analyzed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). Catalyst characterization was performed using Shimadzu XRD-6000.